Xiaowen Jiang

发表

Discovery of novel tacrine derivatives as potent antiproliferative agents with CDKs inhibitory property.

Limeng Wu, Qingchun Zhao, Xin Liu, 2022, Bioorganic chemistry.

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Nan Wang, Zhongchan Wu, Limeng Wu, 2022, European journal of medicinal chemistry.

Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment.

Nan Wang, Qiong Wu, Xiao-wen Jiang, 2022, Bioorganic chemistry.

Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease

Nan Wang, Xiao-wen Jiang, Wenjie Liu, 2021, European Journal of Medicinal Chemistry.

Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.

Qingchun Zhao, H. Ding, Xin Liu, 2021, European journal of medicinal chemistry.

A natural BACE1 and GSK3β dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimer's mice by attenuating amyloid-β and tau pathology.

Huiyuan Gao, Qingchun Zhao, Qinglong Qiao, 2020, Clinical and translational medicine.

A comprehensive description of GluN2B-selective N-methyl-D-aspartate (NMDA) receptor antagonists.

Qingchun Zhao, H. Ding, Yue Yang, 2020, European journal of medicinal chemistry.

Notopterygium incisum extract (NRE) rescues cognitive deficits in APP/PS1 Alzhneimer's disease mice by attenuating amyloid-beta, tau, and neuroinflammation pathology.

Huiyuan Gao, Qingchun Zhao, Qiong Wu, 2019, Journal of ethnopharmacology.

Discovery of novel α‐carboline derivatives as glycogen synthase kinase‐3β inhibitors for the treatment of Alzheimer's disease

Chang Xu, Chengze Zhu, Xiao-wen Jiang, 2022, Archiv der Pharmazie.

Current advances in naturally occurring caffeoylquinic acids: structure, bioactivity and synthesis.

Yue Yang, Xiao-wen Jiang, Huan Gao, 2020, Journal of agricultural and food chemistry.

Yuan-Zhi decoction in the treatment of Alzheimer’s disease: An integrated approach based on chemical profiling, network pharmacology, molecular docking and experimental evaluation

Qingchun Zhao, Xia Li, Qiong Wu, 2022, Frontiers in Pharmacology.

Neuroprotective effects of Kukoamine A against cerebral ischemia via antioxidant and inactivation of apoptosis pathway

Qingchun Zhao, Sen Lin, Xiao-wen Jiang, 2017, Neurochemistry International.

Caffeoylquinic acid derivatives from the roots of Arctium lappa L. (burdock) and their structure–activity relationships (SARs) of free radical scavenging activities

Qiao Zhang, Xing Tian, Junpeng Bai, 2016 .

Network pharmacology-based research uncovers cold resistance and thermogenesis mechanism of Cinnamomum cassia.

Dong-yao, Qingchun Zhao, Zihua Xu, 2020, Fitoterapia.

Cinnamomum cassia extract promotes thermogenesis during exposure to cold via activation of brown adipose tissue.

Qingchun Zhao, Yue Yang, Qiong Wu, 2020, Journal of ethnopharmacology.

Isolation, structure elucidation and neuroprotective effects of caffeoylquinic acid derivatives from the roots of Arctium lappa L.

Qingchun Zhao, Yue Yang, Xiao-wen Jiang, 2020, Phytochemistry.

DHW-221, a Dual PI3K/mTOR Inhibitor, Overcomes Multidrug Resistance by Targeting P-Glycoprotein (P-gp/ABCB1) and Akt-Mediated FOXO3a Nuclear Translocation in Non-small Cell Lung Cancer

Yingshi Zhang, Chang Xu, Qiong Wu, 2022, Frontiers in Oncology.

Novel ADAM-17 inhibitor ZLDI-8 inhibits the proliferation and metastasis of chemo-resistant non-small-cell lung cancer by reversing Notch and epithelial mesenchymal transition in vitro and in vivo.

Qingchun Zhao, Qiong Wu, Xiao-wen Jiang, 2019, Pharmacological research.

CK-3, A Novel Methsulfonyl Pyridine Derivative, Suppresses Hepatocellular Carcinoma Proliferation and Invasion by Blocking the PI3K/AKT/mTOR and MAPK/ERK Pathways

Qingchun Zhao, H. Ding, Baichun Hu, 2021, Frontiers in Oncology.

Kukoamine A Protects against NMDA-Induced Neurotoxicity Accompanied with Down-Regulation of GluN2B-Containing NMDA Receptors and Phosphorylation of PI3K/Akt/GSK-3β Signaling Pathway in Cultured Primary Cortical Neurons

Qingchun Zhao, Yue Yang, Lingyue Gao, 2020, Neurochemical Research.

DCMQA, a caffeoylquinic acid derivative alleviates NMDA-induced neurotoxicity via modulating GluN2A and GluN2B-containing NMDA receptors in vitro.

Tian-shu Ren, Qingchun Zhao, Yue Yang, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Design, synthesis, and biological evaluation of β-carboline 1,3,4-oxadiazole based hybrids as HDAC inhibitors with potential antitumor effects.

H. Ding, Cheng Zhu, Limeng Wu, 2022, Bioorganic & medicinal chemistry letters.

Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition

Qingchun Zhao, H. Ding, Xiao-wen Jiang, 2020, Chinese herbal medicines.

An integrated multi-omics approach revealed the regulation of melatonin on age-dependent mitochondrial function impair and lipid dyshomeostasis in mice hippocampus.

Yingshi Zhang, Nan Wang, Xin Liu, 2022, Pharmacological research.

In Silico Analyses for Key Genes and Molecular Genetic Mechanism in Epilepsy and Alzheimer's Disease.

Qingchun Zhao, Yue Yang, Qiong Wu, 2018, CNS and Neurological Disorders - Drug Targets.

The overlap between Alzheimer's disease and epilepsy uncovered by transcriptome sequencing

Fuhai Hui, Qingchun Zhao, Qiong Wu, 2020, Clinical and translational medicine.

Diagnosis Accuracy and Prognostic Significance of the Dickkopf-1 Protein in Gastrointestinal Carcinomas: Systematic Review and Network Meta-analysis

Yingshi Zhang, Fuhai Hui, Jing Gao, 2020, Journal of Cancer.

Jiang Gui Fang activated interscapular brown adipose tissue and induced epididymal white adipose tissue browning through the PPARγ/SIRT1-PGC1α pathway.

Qingchun Zhao, Xia Li, Yuan Huang, 2020, Journal of ethnopharmacology.

TCQA, A Natural Caffeoylquinic Acid Derivative Attenuates H2O2-Induced Neuronal Apoptosis by Suppressing Phosphorylation of MAPKs Signaling Pathway

Qingchun Zhao, Yufang Ding, Yue Yang, 2021, Planta Medica.

ZLDI-8 suppresses angiogenesis and vasculogenic mimicry in drug-resistant NSCLC in vitro and in vivo.

Qingchun Zhao, Hongyuan Lu, Xiaowen Jiang, 2023, Lung cancer.

Arctium lappa L. roots ameliorates cerebral ischemia through inhibiting neuronal apoptosis and suppressing AMPK/mTOR-mediated autophagy.

Qingchun Zhao, Yue Yang, Qiong Wu, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

The Potential Mechanism of Cannabidiol (CBD) Treatment of Epilepsy in Pentetrazol (PTZ) Kindling Mice Uncovered by Multi-Omics Analysis

M. Wei, Yanyun Zhao, Hongyuan Lu, 2023, Molecules.

Caffeoylquinic Acid Derivatives Protect SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide-Induced Injury Through Modulating Oxidative Status

Qingchun Zhao, Qiao Zhang, Xing Tian, 2016, Cellular and Molecular Neurobiology.

Discovery of novel benzofuro[3,2-b]quinoline derivatives as dual CDK2/Topo I inhibitors.

Chang Xu, Cheng Zhu, Limeng Wu, 2022, Bioorganic chemistry.

An inhibitor with GSK3β and DYRK1A dual inhibitory properties reduces Tau hyperphosphorylation and ameliorates disease in models of Alzheimer's disease

Nan Wang, Wenjun Liu, Limeng Wu, 2023, Neuropharmacology.

Effect of Mirror Therapy on Recovery of Stroke Survivors: A Systematic Review and Network Meta-analysis

Gang Cheng, Yingshi Zhang, Qingchun Zhao, 2018, Neuroscience.

Erratum to: Caffeoylquinic Acid Derivatives Protect SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide-Induced Injury Through Modulating Oxidative Status

Qingchun Zhao, Qiao Zhang, Xing Tian, 2017, Cellular and Molecular Neurobiology.

Design, Synthesis, and Biological Evaluation of Notopterol Derivatives as Triple Inhibitors of AChE/BACE1/GSK3β for the Treatment of Alzheimer’s Disease

Nan Wang, Qiong Wu, Xinming Jiao, 2022, ACS Omega.