Elizabeth Luis

发表

Abstract 4494: A clinical candidate anti-mesothelin-MMAE antibody-drug conjugate (ADC) for therapy of mesothelin-expressing cancers

S. Spencer, L. Berry, D. French, 2014 .

Abstract 4502: Nonclinical characterization and tolerability of a surrogate anti-mesothelin-MMAE antibody-drug conjugate

S. Spencer, D. French, S. Ross, 2014 .

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

P. S. Andersen, Laura DePalatis, Eric J. Brown, 2015, Nature.

Molecular basis for negative regulation of the glucagon receptor

I. Hötzel, A. Estevez, C. Koth, 2012, Proceedings of the National Academy of Sciences.

Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells.

A. Ebens, R. Kelley, M. Junttila, 2014, Cancer research.

An Antibody–Drug Conjugate Targeting the Endothelin B Receptor for the Treatment of Melanoma

P. Polakis, R. Firestein, Janet Y. Tien, 2011, Clinical Cancer Research.

Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor*

I. Hötzel, J. Corn, C. Koth, 2013, The Journal of Biological Chemistry.

Cardiac fibroblasts produce leukemia inhibitory factor and endothelin, which combine to induce cardiac myocyte hypertrophy in vitro

J. Winer, P. Williams, J. Hooley, 1996, Endocrine.

Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B.

F. Peale, M. Tessier-Lavigne, A. Eichmann, 2011, Developmental cell.

Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer

G. Cavet, Xiaolan Hu, J. Zha, 2009, Molecular Cancer Therapeutics.

Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1

Jun Li, Anne Wong, N. van Bruggen, 2011, Science Translational Medicine.

E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis.

S. Marsters, A. Ashkenazi, Lino C. Gonzalez, 2014, Molecular cell.

Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody

Thomas D. Wu, Haiyin Chen-Harris, Min Xu, 2016, PLoS pathogens.

EphB2 as a Therapeutic Antibody Drug Target for the Treatment of Colorectal Cancer

Paul Polakis, H. Koeppen, S. Ross, 2004, Cancer Research.

EphB 2 as a Therapeutic Antibody Drug Target for the Treatment of Colorectal Cancer

H. Koeppen, S. Ross, P. Polakis, 2004 .

An Antibody–Drug Conjugate Directed against Lymphocyte Antigen 6 Complex, Locus E (LY6E) Provides Robust Tumor Killing in a Wide Range of Solid Tumor Malignancies

Karen E Gascoigne, P. Haverty, S. Spencer, 2015, Clinical Cancer Research.

Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET.

Judith E. Flores, Simon-Peter Williams, A. Ogasawara, 2010, Nuclear medicine and biology.

Depletion of major pathogenic cells in asthma by targeting CRTh2.

I. Hötzel, J. Payandeh, D. Yan, 2016, JCI insight.

Functional Consequences of the Macrophage Stimulating Protein 689C Inflammatory Bowel Disease Risk Allele

J. Egen, S. Sa, R. Graham, 2013, PloS one.

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing

Thomas D. Wu, Genee Y. Lee, D. Danilenko, 2017, Cancer cell.

Evolutionarily Conserved Paired Immunoglobulin-like Receptor α (PILRα) Domain Mediates Its Interaction with Diverse Sialylated Ligands

A. Zarrin, Yvonne Chinn, P. Hass, 2012, The Journal of Biological Chemistry.

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.

Min Xu, Charles Eigenbrot, Meijuan Zhou, 2010, The Journal of clinical investigation.

An Antimesothelin-Monomethyl Auristatin E Conjugate with Potent Antitumor Activity in Ovarian, Pancreatic, and Mesothelioma Models

L. Rangell, H. Koeppen, S. Spencer, 2014, Molecular Cancer Therapeutics.

Ai-Luen Wu Fibroblast Growth Factor Receptor 1 Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of

Jun Li, N. Bruggen, A. Peterson, 2011 .

Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models.

H. Koeppen, S. Ross, P. Polakis, 2007, Cancer research.

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

Matthew J. Brauer, N. van Bruggen, M. Brauer, 2015, EBioMedicine.

Murine Insulin Growth Factor-like (IGFL) and Human IGFL1 Proteins Are Induced in Inflammatory Skin Conditions and Bind to a Novel Tumor Necrosis Factor Receptor Family Member, IGFLR1

Wenjun Ouyang, W. Ouyang, A. Lobito, 2011, The Journal of Biological Chemistry.

Defining the Ligand Specificity of the Deleted in Colorectal Cancer (DCC) Receptor

M. Tessier-Lavigne, Lino C. Gonzalez, Bernd J. Wranik, 2014, PloS one.

An antibody drug conjugate (ADC) directed against Lymphocyte Antigen 6 Complex, Locus E (LY6E) provides robust tumor killing in a wide range of solid tumor malignancies Running Title: Preclinical development of a LY6E antibody drug conjugate

Karen E Gascoigne, P. Haverty, S. Spencer, 2015 .

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

Z. Modrušan, W. Ouyang, Harinder Singh, 2011, Nature Immunology.