G. Quinlan

发表

Increased plasma thioredoxin levels in patients with sepsis: positive association with macrophage migration inhibitory factor

T. Evans, N. MacCallum, S. Leaver, 2009, Intensive Care Medicine.

The effect of cardiopulmonary bypass on intestinal and pulmonary endothelial permeability.

J. Pepper, P. Haslam, G. J. Quinlan, 1995, Chest.

The pathogenesis of lung injury following pulmonary resection.

T. Evans, S. Jordan, P. Goldstraw, 2000, The European respiratory journal.

Hydroxyl radical generation by the tetracycline antibiotics with free radical damage to DNA, lipids and carbohydrate in the presence of iron and copper salts.

J. Gutteridge, G. J. Quinlan, G. Quinlan, 1988, Free radical biology & medicine.

Oxygen radical damage to DNA by rifamycin SV and copper ions.

J. Gutteridge, G. Quinlan, 1987, Biochemical pharmacology.

Albumin influences total plasma antioxidant capacity favorably in patients with acute lung injury*

G. Bernard, G. Martin, T. Evans, 2004, Critical care medicine.

Albumin: Biochemical properties and therapeutic potential

G. Martin, T. Evans, Gregory J. Quinlan, 2005, Hepatology.

Ferrous ion formation by ferrioxamine prepared from aged desferrioxamine: a potential prooxidant property.

J. Gutteridge, G. J. Quinlan, J. Swain, 1994, Free radical biology & medicine.

Thiols in cellular redox signalling and control.

J. Gutteridge, G. J. Quinlan, L. K. Moran, 2001, Current medicinal chemistry.

Malondialdehyde formation from lipid peroxides in the thiobarbituric acid test: the role of lipid radicals, iron salts, and metal chelators.

J. Gutteridge, G. J. Quinlan, G. Quinlan, 1983, Journal of applied biochemistry.

Identification and determination of the qualitative composition of nystatin using thin-layer chromatography and high-performance liquid chromatography

B. Pharm, P. Newland, A. Thomas, 1981 .

Phagomimetic action of antimicrobial agents.

P. Kovacic, J. Gutteridge, G. Quinlan, 1998, Free radical research.

Thioredoxin in sepsis: Just another biomarker or a plausible therapeutic target?

T. Evans, G. J. Quinlan, A. Burke-Gaffney, 2009, Critical care medicine.

Antioxidant protection against organic and inorganic oxygen radicals by normal human plasma: the important primary role for iron-binding and iron-oxidising proteins.

J. Gutteridge, G. Quinlan, John M.C. Gutteridge, 1992, Biochimica et biophysica acta.

Aluminium salts accelerate peroxidation of membrane lipids stimulated by iron salts.

B. Halliwell, J. Gutteridge, J. Gutteridge, 1985, Biochimica et biophysica acta.

Action of lead(II) and aluminium (III) ions on iron-stimulated lipid peroxidation in liposomes, erythrocytes and rat liver microsomal fractions.

B. Halliwell, J. Gutteridge, J. Gutteridge, 1988, Biochimica et biophysica acta.

Assay of doxorubicin and 4'-epidoxorubicin by reversed-phase ion-pair chromatography.

J. Gutteridge, A. Thomas, G. Quinlan, 1984, Journal of chromatography.

Administration of albumin to patients with sepsis syndrome: a possible beneficial role in plasma thiol repletion.

T. Evans, J. Gutteridge, J. Gutteridge, 1998, Clinical science.

Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: evidence for neutrophil-mediated hydroxylation, nitration, and chlorination.

T. Evans, J. Gutteridge, G. J. Quinlan, 1999, Critical care medicine.

Chelatable iron and copper can be released from extracorporeally circulated blood during cardiopulmonary bypass

N. Moat, J. Gutteridge, G. J. Quinlan, 1993, FEBS letters.

Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping

E. Want, N. MacCallum, J. Mitchell, 2018, Scientific Reports.

Oxidative damage to DNA and deoxyribose by beta-lactam antibiotics in the presence of iron and copper salts.

J. Gutteridge, G. Quinlan, 1988, Free radical research communications.

Antioxidant protection against iron in children with meningococcal sepsis

M. Festa, J. Gutteridge, S. Nadel, 2002, Critical care medicine.

Carminic acid-promoted oxygen radical damage to lipid and carbohydrate.

J. Gutteridge, G. Quinlan, 1986, Food additives and contaminants.

Iron‐binding Affinity of Bacterial Vaccine Polysaccharides which Contain Phosphodiester Linkages as Part of the Polymer Chain and of Other Polyphosphates, Including DNA

E. Tarelli, G. J. Quinlan, B. Bingham, 1994, The Journal of pharmacy and pharmacology.

Pulmonary Arterial Hypertension: Iron Matters

S. Wort, L. Ramakrishnan, Sofia L. Pedersen, 2018, Front. Physiol..

Redox regulation of neutrophil apoptosis and the systemic inflammatory response syndrome.

T. Evans, Daniel D. Melley, D. Melley, 2005, Clinical science.

Reactive Oxygen and Reactive Nitrogen Species in the Lung

N. J. Lamb, G. Quinlan, 2000 .

Superoxide-dependent lipid peroxidation. Problems with the use of catalase as a specific probe for fenton-derived hydroxyl radicals.

J. Gutteridge, G. J. Quinlan, A. P. Beard, 1983, Biochemical and biophysical research communications.

Variable tissue expression of transferrin receptors: relevance to acute respiratory distress syndrome

A. Nicholson, R. L. Upton, J. Gutteridge, 2003, European Respiratory Journal.

Oxidative damage to plasma proteins in adult respiratory distress syndrome.

T. Evans, J. Gutteridge, G. Quinlan, 1994, Free radical research.

Variation in iron homeostasis genes between patients with ARDS and healthy control subjects.

T. Evans, K. Welsh, R. D. du Bois, 2008, Chest.

Clotting Dysfunction in Sepsis: A Role for ROS and Potential for Therapeutic Intervention

M. Lopes-Pires, Jéssica O Frade-Guanaes, G. Quinlan, 2021, Antioxidants.

Characterization of the vasodilator properties of peroxynitrite on rat pulmonary artery: role of poly (adenosine 5′‐diphosphoribose) synthase

T. Evans, François Chabot, J. Mitchell, 1997, British journal of pharmacology.

Pulmonary oxidant stress in murine sepsis is due to inflammatory cell nitric oxide*

Lefeng Wang, H. Razavi, D. McCormack, 2005, Critical care medicine.

The “Iron”‐y of Iron Overload and Iron Deficiency in Chronic Obstructive Pulmonary Disease

I. Adcock, K. Chung, A. Choi, 2017, American journal of respiratory and critical care medicine.

Postoperative lung injury and oxidative damage in patients undergoing pulmonary resection.

T. Evans, P. Goldstraw, G. J. Quinlan, 1998, The European respiratory journal.

Plasma hypoxanthine levels in ARDS: implications for oxidative stress, morbidity, and mortality.

T. Evans, R. Tilley, J. Gutteridge, 1997, American journal of respiratory and critical care medicine.

Production of nitric oxide during surgery involving cardiopulmonary bypass.

J. Pepper, T. Evans, S. Brett, 1998, Critical care medicine.

Decreased breath excretion of redox active iron in COPD: a protective failure?

I. Adcock, K. Chung, J. Saito, 2015, European Respiratory Journal.

Aluminium-adjuvanted vaccines transiently increase aluminium levels in murine brain tissue.

R. G. Das, J. Gutteridge, K. Redhead, 1992, Pharmacology & toxicology.

PMX464, a thiol-reactive quinol and putative thioredoxin inhibitor, inhibits NF-κB-dependent proinflammatory activation of alveolar epithelial cells

T. Evans, M. Griffiths, A. Westwell, 2008, British journal of pharmacology.

Arterial carboxyhemoglobin level and outcome in critically ill patients*

T. Evans, Daniel D. Melley, S. Finney, 2007, Critical care medicine.

Lung heme oxygenase-1 is elevated in acute respiratory distress syndrome

A. Nicholson, T. Evans, R. Upton, 2004, Critical care medicine.

Iron signalling regulated directly and through oxygen: implications for sepsis and the acute respiratory distress syndrome.

T. Evans, J. Gutteridge, Y. Chen, 2001, Clinical science.

Plasma fatty acid changes and increased lipid peroxidation in patients with adult respiratory distress syndrome.

T. Evans, J. Gutteridge, G. J. Quinlan, 1996, Critical care medicine.

4-hydroxy-2-nonenal levels increase in the plasma of patients with adult respiratory distress syndrome as linoleic acid appears to fall.

T. Evans, J. Gutteridge, G. J. Quinlan, 1994, Free radical research.

Haem oxygenase shows pro-oxidant activity in microsomal and cellular systems: implications for the release of low-molecular-mass iron

T. Evans, J. Gutteridge, G. J. Quinlan, 1999 .

The RAGE axis in systemic inflammation, acute lung injury and myocardial dysfunction: an important therapeutic target?

T. Evans, B. Creagh-Brown, A. Burke‐Gaffney, 2010, Intensive Care Medicine.

Extracellular thioredoxin levels are increased in patients with acute lung injury

A. Nicholson, T. Evans, H. Nakamura, 2006, Thorax.

Free radical damage to deoxyribose by anthracycline, aureolic acid and aminoquinone antitumour antibiotics. An essential requirement for iron, semiquinones and hydrogen peroxide.

J. Gutteridge, G. J. Quinlan, G. Quinlan, 1985, Biochemical pharmacology.

Antioxidant protection against organic and inorganic oxygen radicals by normal human plasma: the important primary role for iron-binding and iron-oxidising proteins.

J. Gutteridge, G. Quinlan, 1993, Biochimica et biophysica acta.

Association between Preoperative Plasma sRAGE Levels and Recovery from Cardiac Surgery

T. Evans, B. Creagh-Brown, G. J. Quinlan, 2013, Mediators of inflammation.

Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone.

K. Chung, P. Barnes, M. Salmon, 1998, American journal of respiratory and critical care medicine.

Plasma S100A8/A9 heterodimer is an early prognostic marker of acute kidney injury associated with cardiac surgery.

T. Evans, B. Creagh-Brown, Z. Nikolakopoulou, 2019, Biomarkers in medicine.

Acute respiratory distress syndrome secondary to cardiopulmonary bypass: Do compromised plasma iron-binding antioxidant protection and thiol levels influence outcome?

T. Evans, J. Gutteridge, G. J. Quinlan, 2000, Critical care medicine.

S92 Hepcidin and interleukin-6 downregulate BMPR2 and dysregulate BMPR2 downstream pathways; implications for pulmonary artery hypertension

S. Wort, I. Panselinas, G. Quinlan, 2021 .

Phagomimetic action of antibiotics: Revisited. How do antibiotics know where to go?

P. Kovacic, J. Gutteridge, G. Quinlan, 2019, Biochemical and biophysical research communications.

Pathogenesis of the systemic inflammatory syndrome and acute lung injury: role of iron mobilization and decompartmentalization.

T. Evans, Daniel D. Melley, G. J. Quinlan, 2008, American journal of physiology. Lung cellular and molecular physiology.

Regionalization of critical care: Not just for kids*

T. Evans, A. Burke-Gaffney, G. Quinlan, 2009 .

The Hepcidin/Ferroportin axis modulates proliferation of pulmonary artery smooth muscle cells

S. Wort, A. Lawrie, L. Ramakrishnan, 2018, Scientific Reports.

Iron and the redox status of the lungs.

T. Evans, J. Gutteridge, G. J. Quinlan, 2002, Free radical biology & medicine.

Ischaemia--reperfusion injury in the rat is modulated by superoxide generation and leads to an augmentation of the hypoxic pulmonary vascular response.

T. Evans, M. Griffiths, J. Gutteridge, 1996, Clinical science.

Reactive Oxygen Species, Antioxidant Protection and Lung Injury

J. Gutteridge, G. J. Quinlan, G. Quinlan, 1996 .

The iron paradox of heart and lungs and its implications for acute lung injury

T. Evans, J. Gutteridge, G. J. Quinlan, 2001, Free radical research.

Metabolomic profiling of amines in sepsis predicts changes in NOS canonical pathways

E. Want, N. MacCallum, J. Mitchell, 2017, PloS one.

Bacitracin and a bacitracin-zinc complex damage DNA and carbohydrate in the presence of iron and copper salts.

J. Gutteridge, G. Quinlan, 1989, Free Radical Research Communications.

DNA base damage by beta-lactam, tetracycline, bacitracin and rifamycin antibacterial antibiotics.

J. Gutteridge, G. Quinlan, 1991, Biochemical pharmacology.

Heme Oxygenase and Acute Lung Injury: The Functional Significance of Heme Oxygenase Induction

T. Evans, G. J. Quinlan, N. J. Lamb, 1999 .

Nitration of proteins in bronchoalveolar lavage fluid from patients with acute respiratory distress syndrome receiving inhaled nitric oxide.

T. Evans, J. Gutteridge, S. Westerman, 1999, American journal of respiratory and critical care medicine.

Biomarkers of lung injury after one‐lung ventilation for lung resection

M. Griffiths, S. Davidson, Hiroe Sato, 2011, Respirology.

Exhaled breath condensate detects markers of pulmonary inflammation after cardiothoracic surgery.

M. Griffiths, S. Kharitonov, G. J. Quinlan, 2004, American journal of respiratory and critical care medicine.

Haem oxygenase shows pro-oxidant activity in microsomal and cellular systems: implications for the release of low-molecular-mass iron.

T. Evans, J. Gutteridge, J. Gutteridge, 1999, The Biochemical journal.

Is bleomycin-detectable iron present in the plasma of patients with septic shock?

T. Evans, J. Gutteridge, S. Mumby, 1997, Intensive Care Medicine.

Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells.

T. Evans, M. Griffiths, L. Ramakrishnan, 2014, American journal of physiology. Lung cellular and molecular physiology.

Modified criteria for the systemic inflammatory response syndrome improves their utility following cardiac surgery.

T. Evans, N. MacCallum, S. Finney, 2014, Chest.

Lung injury following pulmonary resection in the isolated, blood-perfused rat lung.

T. Evans, P. Goldstraw, G. J. Quinlan, 1999, The European respiratory journal.

The Role of Neutrophil-Derived Myeloperoxidase in Organ Dysfunction and Sepsis

T. Evans, N. MacCallum, G. J. Quinlan, 2007 .

Persistently low plasma thioredoxin is associated with meningococcal septic shock in children

T. Evans, M. Callister, S. Nadel, 2007, Intensive Care Medicine.

Pro-oxidant iron in exhaled breath condensate: a potential excretory mechanism.

K. Chung, M. Griffiths, G. J. Quinlan, 2011, Respiratory medicine.

Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping

E. Want, N. MacCallum, J. Mitchell, 2018, Scientific Reports.

Linoleic acid and protein thiol changes suggestive of oxidative damage in the plasma of patients with adult respiratory distress syndrome.

T. Evans, J. Gutteridge, G. J. Quinlan, 1994, Free radical research.

Systemic inflammation and oxidative stress post‐lung resection: Effect of pretreatment with N‐acetylcysteine

M. Griffiths, E. Lim, N. Davies, 2016, Respirology.

Transient iron overload with bleomycin detectable iron in the plasma of patients with adult respiratory distress syndrome.

T. Evans, J. Gutteridge, G. J. Quinlan, 1994, Thorax.

Acute respiratory distress syndrome in adults.

T. Evans, G. J. Quinlan, G. Quinlan, 2000, Hospital medicine.

Primary plasma antioxidants in adult respiratory distress syndrome patients: changes in iron-oxidizing, iron-binding, and free radical-scavenging proteins.

T. Evans, J. Gutteridge, G. J. Quinlan, 1994, The Journal of laboratory and clinical medicine.

Hypothesis: are fatty acid patterns characteristic of essential fatty acid deficiency indicative of oxidative stress?

Y. Yamamoto, J. Gutteridge, G. J. Quinlan, 1998, Free radical research.

Mitomycin C‐induced deoxyribose degradation inhibited by superoxide dismutase

J. Gutteridge, Stephanie Wilkins, G. Quinlan, 1984, FEBS letters.

Iron overload upregulates haem oxygenase 1 in the lung more rapidly than in other tissues

T. Evans, J. Gutteridge, G. J. Quinlan, 1999, FEBS Letters.

Pro-oxidant iron is present in human pulmonary epithelial lining fluid: implications for oxidative stress in the lung.

K. Chung, T. Evans, K. Chung, 1996, Biochemical and biophysical research communications.

Haem oxygenase-1 polymorphism and ARDS, friend and foe?

T. Evans, G. J. Quinlan, A. Lagan, 2009, Intensive Care Medicine.

Pulmonary vascular permeability after cardiopulmonary bypass and its relationship to oxidative stress.

T. Evans, J. Gutteridge, G. J. Quinlan, 1997, Critical care medicine.

Vanadium and copper in clinical solutions of albumin and their potential to damage protein structure.

C. Coudray, J. Gutteridge, A. Hubbard, 1992, Journal of pharmaceutical sciences.

Extracellular thioredoxin levels are increased in patients with acute lung injury

A. Nicholson, T. Evans, H. Nakamura, 2006 .

Haem oxygenase: A model for therapeutic intervention

T. Evans, A. Lagan, G. Quinlan, 2008, Intensive Care Medicine.

KL‐6 levels are elevated in plasma from patients with acute respiratory distress syndrome

T. Evans, K. Welsh, M. Callister, 2004, European Respiratory Journal.