R. Ettinger

发表

Factor VIII gene variants and inhibitor risk in African American hemophilia A patients.

M. Epstein, E. James, Janice S. Withycombe, 2014, Blood.

FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity.

E. James, A. Thompson, K. Pratt, 2018, Blood advances.

Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses.

D. Scott, S. Rieder, E. Shevach, 2015, Blood.

HLA‐DR‐restricted T‐cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P

E. James, W. Kwok, A. Thompson, 2010, Haemophilia : the official journal of the World Federation of Hemophilia.

Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.

E. James, W. Kwok, A. Thompson, 2009, Blood.

Sequence-Modified Factor VIII Variants Having Reduced Immunogenicity

M. Epstein, E. James, K. Pratt, 2012 .

T‐cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site

J. Voorberg, S. V. van Haren, E. James, 2011, Journal of thrombosis and haemostasis : JTH.

High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance.

K. Lewis, S. Meeks, J. Healey, 2014, Blood.

THROMBOSIS AND HEMOSTASIS High-resolution mapping of epitopes on the C 2 domain of factor VIII by analysis of point mutants using surface plasmon resonance

K. Lewis, S. Meeks, J. Healey, 2014 .

T‐cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self‐peptide

E. James, W. Kwok, A. Thompson, 2007, Journal of thrombosis and haemostasis : JTH.

T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.

P. Paz, E. James, A. Thompson, 2016, Blood.

Engineered antigen-speci fi c human regulatory T cells : immunosuppression of FVIII-speci fi c T-and B-cell responses

D. Scott, S. Rieder, E. Shevach, 2015 .

Six Amino Acid Residues in a 1200 Å2 Interface Mediate Binding of Factor VIII to an IgG4κ Inhibitory Antibody

A. Thompson, K. Pratt, Jasper C. Lin, 2015, PloS one.

HLA-DQ Tetramers Identify Epitope-Specific T Cells in Peripheral Blood of Herpes Simplex Virus Type 2-Infected Individuals: Direct Detection of Immunodominant Antigen-Responsive Cells1

Andrew W. Liu, J. Gebe, G. Nepom, 2000, The Journal of Immunology.

Allelic Variation in Key Peptide-Binding Pockets Discriminates between Closely Related Diabetes-Protective and Diabetes-Susceptible HLA-DQB1*06 Alleles1

G. Nepom, W. Kwok, A. Moustakas, 2006, The Journal of Immunology.

Diabetes-Susceptible Related Diabetes-Protective and Pockets Discriminates between Closely Allelic Variation in Key Peptide-Binding

G. Nepom, W. Kwok, A. Moustakas, 2006 .

Open reading frame sequencing and structure-based alignment of polypeptides encoded by RT1-Bb, RT1-Ba, RT1-Db, and RT1-Da alleles

A. Moustakas, R. Ettinger, Suzanne D. Lobaton, 2004, Immunogenetics.

Mutational analysis of critical residues determining antigen presentation and activation of HLA-DQ0602 restricted T-cell clones.

Andrew W. Liu, G. Nepom, W. Kwok, 2002, Human immunology.

A peptide binding motif for HLA-DQA1*0102/DQB1*0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus.

W. Kwok, R. A. Ettinger, R. Ettinger, 1998, Journal of immunology.

Insulin-Dependent Diabetes Mellitus Molecule Associated with Dominant Protection in MHCHLA-DQA 1 * 0102 / DQB 1 * 0602 , the Class II A Peptide Binding Motif for

W. Kwok, R. A. Ettinger, R. Ettinger, 1998 .

Exceptional Stability of the HLA-DQA1*0102/DQB1*0602 αβ Protein Dimer, the Class II MHC Molecule Associated with Protection from Insulin-Dependent Diabetes Mellitus

Andrew W. Liu, G. Nepom, W. Kwok, 1998, The Journal of Immunology.

IL-17 Is Secreted by T-Cell Clones Isolated Following An Initial Peak Inhibitor Response to Factor VIIII, Suggesting Th17 Cells Play a Role in Inhibitor Development

E. James, W. Kwok, A. Thompson, 2008 .

Antigen-Responsive Cells Direct Detection of Immunodominant Simplex Virus Type 2-Infected Individuals : T Cells in Peripheral Blood of Herpes HLA-DQ Tetramers Identify Epitope-Specific

Andrew W. Liu, J. Gebe, G. Nepom, 2000 .

Autoantibody epitopes to the smaller isoform of glutamate decarboxylase do not differ in Swedish and Japanese type 1 diabetes patients and may be associated with high‐risk human leucocyte antigen class II alleles

J. Banga, S. Oak, J. Endl, 2007, Clinical and experimental immunology.

Distinct T Cell Interactions with HLA Class II Tetramers Characterize a Spectrum of TCR Affinities in the Human Antigen-Specific T Cell Response1

Andrew W. Liu, J. Gebe, G. Nepom, 2000, The Journal of Immunology.

Antigen-Specific T Cell TCR Affinities in the Human II Tetramers Characterize a Spectrum of Distinct T Cell Interactions with HLA Class

Andrew W. Liu, G. Nepom, W. Kwok, 2000 .

β57-Asp Plays an Essential Role in the Unique SDS Stability of HLA-DQA1*0102/DQB1*0602 αβ Protein Dimer, the Class II MHC Allele Associated with Protection from Insulin-Dependent Diabetes Mellitus1

Andrew W. Liu, G. Nepom, W. Kwok, 2000, The Journal of Immunology.

Diabetes Mellitus with Protection from Insulin-Dependent Dimer , the Class II MHC Allele Associated Protein βα HLA-DQA 1 * 0102 / DQB 1 * 0602 Unique SDS Stability of 57-Asp Plays an Essential Role in the β

Andrew W. Liu, G. Nepom, W. Kwok, 2000 .

Diabetes Mellitus with Protection from Insulin-Dependent AssociatedDimer , the Class II MHC Molecule Protein βα HLA-DQA 1 * 0102 / DQB 1 * 0602 Exceptional Stability of the

Andrew W. Liu, G. Nepom, W. Kwok, 1998 .

Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat.

E. Lander, Å. Lernmark, H. Jacob, 2004, Physiological genomics.

Non-Genetically Encoded Epitopes Are Relevant Targets in Autoimmune Diabetes

E. James, Perrin Guyer, Hai Nguyen, 2021, Biomedicines.

Sequence Variation and Expression of the Gimap Gene Family in the BB Rat

Å. Lernmark, A. Kwitek, B. van Yserloo, 2009, Experimental diabetes research.

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.

Eric S Lander, Ben Snyder, Anne E Kwitek, 2002, Genome research.

The Vitamin D Endocrine System and Its Therapeutic Potential

H. DeLuca, R. Ettinger, 1996 .

BB rat Gimap gene expression in sorted lymphoid T and B cells.

Å. Lernmark, A. Kwitek, B. van Yserloo, 2011, Life sciences.

Beta 57-Asp plays an essential role in the unique SDS stability of HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC allele associated with protection from insulin-dependent diabetes mellitus.

G. Nepom, W. Kwok, A. Liu, 2000, Journal of immunology.

Immunopurified 25-hydroxyvitamin D 1 alpha-hydroxylase and 1,25-dihydroxyvitamin D 24-hydroxylase are closely related but distinct enzymes.

H. DeLuca, J. Prahl, M. Burgos-Trinidad, 1992, The Journal of biological chemistry.

cDNA cloning and characterization of a vitamin D3 hydroxylase-associated protein.

H. DeLuca, R. Ettinger, R. Ismail, 1994, The Journal of biological chemistry.

Phenotypes of Allo- and Autoimmune Antibody Responses to FVIII Characterized by Surface Plasmon Resonance

M. Epstein, K. Lewis, C. Kempton, 2013, PloS one.

Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.

G. Nepom, W. Kwok, A. Liu, 1998, Journal of immunology.

The vitamin D3 hydroxylase-associated protein is a propionamide-metabolizing amidase enzyme.

H. DeLuca, R. Ettinger, 1995, Archives of biochemistry and biophysics.

Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study.

H. Reijonen, E. James, W. Kwok, 2023, The Journal of clinical endocrinology and metabolism.

BB rat Gimap gene expression in sorted lymphoid T and B cells.

Å. Lernmark, A. Kwitek, B. van Yserloo, 2011, Life sciences.

Molecular aspects of HLA class II alphabeta heterodimers associated with IDDM susceptibility and protection.

G. Nepom, R. Ettinger, 2000, Reviews in immunogenetics.