M. Coupal

发表

Delta agonist hydroxy bioisosteres: the discovery of 3-((1-benzylpiperidin-4-yl){4-[(diethylamino)carbonyl]phenyl}amino)benzamide with improved delta agonist activity and in vitro metabolic stability.

L. Adam, P. Morin, C. Walpole, 2009, Bioorganic & Medicinal Chemistry Letters.

N,N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: the development of diaryl amino piperidines as potent delta opioid receptor agonists with in vivo anti-nociceptive activity in rodent models.

D. Delorme, Paul B. Jones, E. Roberts, 2009, Bioorganic & Medicinal Chemistry Letters.

Discovery of mu-opioid selective ligands derived from 1-aminotetralin scaffolds made via metal-catalyzed ring-opening reactions.

M. Lautens, C. Dockendorff, Nathan Spear, 2009, Bioorganic & medicinal chemistry letters.

Broad analgesic activity of a novel, selective M1 agonist

P. Schroeder, J. Laird, J. Sandin, 2017, Neuropharmacology.

New scaffolds in the development of mu opioid-receptor ligands.

D. Pagé, Natalie N. M. Nguyen, L. Adam, 2003, Bioorganic & medicinal chemistry letters.

The M1/M4 preferring agonist xanomeline is analgesic in rodent models of chronic inflammatory and neuropathic pain via central site of action

Xiao Hong Yu, J. Laird, N. Markoglou, 2011, PAIN.

Discovery and Pharmacological Characterization of a Small-Molecule Antagonist at Neuromedin U Receptor NMUR2

S. Trivedi, Jian Huang, Jay Liu, 2009, Journal of Pharmacology and Experimental Therapeutics.

Preclinical Pharmacology of AZD2327: A Highly Selective Agonist of the δ-Opioid Receptor

T J Hudzik, Michael D B Swedberg, K. Bui, 2011, Journal of Pharmacology and Experimental Therapeutics.

Development of p-benzoylbenzoylated [N,C,rANP(1-28)]pBNP32 (pBNP1) derivatives and affinity photolabeling of the bovine NPR-A receptor.

A. Fournier, A. De Léan, N. McNicoll, 1999, Biochemical and biophysical research communications.

Photolabeling study of the ligand binding domain of natriuretic peptide receptor A: development of a model.

A. Fournier, A. De Léan, N. McNicoll, 2005, Biochemistry.

Novel C-terminus modifications of the Dmt-Tic motif: a new class of dipeptide analogues showing altered pharmacological profiles toward the opioid receptors.

D. Pagé, R. Schmidt, K. Payza, 2001, Journal of Medicinal Chemistry.