Islam R Younis

发表

In vitro elucidation of the metabolic fate of the anticancer drug busulfan

I. Younis, Islam R Younis, 2008 .

Treatment and Prevention of CMV Disease in Transplant Recipients: Current Knowledge and Future Perspectives

M. Sampson, I. Younis, A. Pikis, 2018, Journal of clinical pharmacology.

Epoxidation of the methamphetamine pyrolysis product, trans-phenylpropene, to trans-phenylpropylene oxide by CYP enzymes and stereoselective glutathione adduct formation.

P. Gannett, T. Tracy, P. Callery, 2006, Toxicology and applied pharmacology.

Methadone Metabolism and Drug-Drug Interactions: In Vitro and In Vivo Literature Review.

Vikram Patel, I. Younis, C. Sahajwalla, 2018, Journal of pharmaceutical sciences.

Design Features of Drug–Drug Interaction Trials Between Antivirals and Oral Contraceptives

Rubén Ayala, V. Arya, Islam R Younis, 2016, Journal of clinical pharmacology.

A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE)

H. Hurwitz, J. Bendell, G. Blobe, 2011, Cancer Chemotherapy and Pharmacology.

Phase I evaluation of gemcitabine, mitoxantrone, and their effect on plasma disposition of fludarabine in patients with relapsed or refractory acute myeloid leukemia

David John Adams, B. Peterson, C. Decastro, 2008, Leukemia & lymphoma.

Clinical pharmacology of an atrasentan and docetaxel regimen in men with hormone-refractory prostate cancer

T. J. Mcmanus, G. Hobbs, A. Armstrong, 2014, Cancer Chemotherapy and Pharmacology.

Effects of Tobacco Smoking and Nicotine on Cancer Treatment

S. Weed, W. Petros, Islam R Younis, 2012, Pharmacotherapy.

Drug‐Drug Interaction Studies of Methadone and Antiviral Drugs: Lessons Learned

Vikram Patel, C. Sahajwalla, D. Volpe, 2019, Journal of clinical pharmacology.

Assessment of Hepatic Impairment and Implications for Pharmacokinetics of Substance Use Treatment

C. Venuto, A. Talal, Islam R Younis, 2017, Clinical pharmacology in drug development.

An integrated clinical pharmacology approach for deriving dosing recommendations in a regulatory setting: Review of recent cases in psychiatry drugs

Hao Zhu, M. Mehta, Hobart L Rogers, 2013, Journal of clinical pharmacology.

An Integrated Approach for Establishing Dosing Recommendations: Paliperidone for the Treatment of Adolescent Schizophrenia

J. Gobburu, I. Younis, Yaning Wang, 2013, Journal of clinical psychopharmacology.

Metabolism of the Cysteine S-Conjugate of Busulfan Involves a β-Lyase Reaction

W. Petros, Arthur James Cooper, P. Callery, 2008, Drug Metabolism and Disposition.

Longitudinal Comparison of Thyroxine Pharmacokinetics Between Pregnant and Nonpregnant Women: A Stable Isotope Study

A. Vinks, O. Soldin, H. Landy, 2010, Therapeutic drug monitoring.

Overview of Clinical Pharmacology Packages of New Drug Applications Approved for the Treatment of Rare Diseases

H. Hassan, H. Qosa, Islam R Younis, 2022, Journal of clinical pharmacology.

Dosing Recommendations for Quetiapine When Coadministered With HIV Protease Inhibitors

P. Zhao, M. Sampson, Paula Gish, 2018, Journal of clinical pharmacology.

Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite

Y. Rojanasakul, S. Leonard, P. Gannett, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Dehydroalanine Analog of Glutathione: An Electrophilic Busulfan Metabolite That Binds to Human Glutathione S-Transferase A1-1

W. Petros, Arthur James Cooper, C. Peer, 2008, Journal of Pharmacology and Experimental Therapeutics.

Enterohepatic recirculation model of irinotecan (CPT-11) and metabolite pharmacokinetics in patients with glioma

H. Friedman, L. Schaaf, W. Petros, 2009, Cancer Chemotherapy and Pharmacology.

The Trend of Increasing Placebo Response and Decreasing Treatment Effect in Schizophrenia Trials Continues: An Update From the US Food and Drug Administration.

R. Uppoor, Hao Zhu, M. Gopalakrishnan, 2020, The Journal of clinical psychiatry.

Influence of pH on the dissolution of folic acid supplements.

P. Callery, I. Younis, M. Stamatakis, 2009, International journal of pharmaceutics.

Pharmaceutical quality performance of folic acid supplements

Islam R Younis, 2003 .

Stable Isotope Pharmacokinetic Studies Provide Insight into Effects of Age, Sex, and Weight on Levothyroxine Metabolism.

J. Jonklaas, O. Soldin, K. Burman, 2018, Thyroid : official journal of the American Thyroid Association.

Association of End Point Definition and Randomized Clinical Trial Duration in Clinical Trials of Schizophrenia Medications.

R. Uppoor, Hao Zhu, M. Gopalakrishnan, 2020, JAMA psychiatry.

Direct-injection mass spectrometric method for the rapid identification of fentanyl and norfentanyl in postmortem urine of six drug-overdose cases.

C. Peer, P. Callery, Diaá M. Shakleya, 2007, Journal of analytical toxicology.

Evaluation of US Food and Drug Administration Drug Label Recommendations for Coadministration of Antivirals and Acid‐Reducing Agents

P. Marroum, T. Skaar, Nicholas R. Powell, 2022, Clinical pharmacology and therapeutics.

Assessment of Similarity in Antipsychotic Exposure‐Response Relationships in Clinical Trials Between Adults and Adolescents With Acute Exacerbation of Schizophrenia

R. Uppoor, I. Younis, Hao Zhu, 2020, Journal of clinical pharmacology.

A Quantitative Justification of Similarity in Placebo Response Between Adults and Adolescents With Acute Exacerbation of Schizophrenia in Clinical Trials

R. Uppoor, Hao Zhu, M. Gopalakrishnan, 2019, Clinical pharmacology and therapeutics.

Pharmacokinetics, pharmacodynamics, safety and tolerability of cilofexor, a novel nonsteroidal Farnesoid X receptor agonist, in healthy volunteers

T. Watkins, A. Billin, Deqing Xiao, 2022, Clinical and translational science.

Adverse Event Detection and Labeling in Pediatric Drug Development: Antiretroviral Drugs

D. Abernethy, E. Capparelli, J. Momper, 2015, Therapeutic innovation & regulatory science.

Effect of Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor Agonist

Mun Sang Yue, T. Watkins, A. Billin, 2023, Journal of clinical pharmacology.

Trends in FDA Transporter‐Based Post‐Marketing Requirements and Commitments Over the Last Decade

I. Younis, H. Hassan, Pooja Manchandani, 2022, Clinical pharmacology and therapeutics.

Utility of Model‐Based Approaches for Informing Dosing Recommendations in Specific Populations: Report From the Public AAPS Workshop

B. Corrigan, N. Stockbridge, P. Zhao, 2016, Journal of clinical pharmacology.