J. Brewer

发表

Production of IgM hexamers by normal and autoimmune B cells: implications for the physiologic role of hexameric IgM.

J. W. Brewer, A. Colosia, W. Rosse, 1998, Journal of immunology.

BiP and immunoglobulin light chain cooperate to control the folding of heavy chain and ensure the fidelity of immunoglobulin assembly.

L. Hendershot, Y. Lee, J. Brewer, 1999, Molecular biology of the cell.

Building an antibody factory: a job for the unfolded protein response

J. W. Brewer, L. Hendershot, J. Brewer, 2004, Nature Immunology.

The Unfolded Protein Response (UPR)-activated Transcription Factor X-box-binding Protein 1 (XBP1) Induces MicroRNA-346 Expression That Targets the Human Antigen Peptide Transporter 1 (TAP1) mRNA and Governs Immune Regulatory Genes*

Niren Kapoor, Rafał Bartoszewski, Z. Bebők, 2011, The Journal of Biological Chemistry.

Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response.

L. Hendershot, J. Diehl, Yanjun Ma, 2002, Journal of molecular biology.

Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation.

C. Nicchitta, J. W. Brewer, S. Stephens, 2005, Molecular biology of the cell.

Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression.

C. Sherr, J. W. Brewer, L. Hendershot, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)

Xiaozhong Wang, X. Wang, B. Lawson, 1996, Molecular and cellular biology.

PERK mediates cell-cycle exit during the mammalian unfolded protein response.

J. W. Brewer, J. Diehl, J A Diehl, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Roles of heavy and light chains in IgM polymerization.

H. Jäck, G. Beck-Engeser, R. Corley, 1995, Proceedings of the National Academy of Sciences of the United States of America.

MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response

A. Byrd, I. Aragon, J. Brewer, 2012, The Journal of cell biology.

Micro(RNA)managing Endoplasmic Reticulum Stress

J. W. Brewer, A. Byrd, J. Brewer, 2013, IUBMB life.

A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non‐stressed cells

J. Cleveland, J. W. Brewer, L. Hendershot, 1997, The EMBO journal.

Coordinate Regulation of Phospholipid Biosynthesis and Secretory Pathway Gene Expression in XBP-1(S)-induced Endoplasmic Reticulum Biogenesis*

J. W. Brewer, G. L. Buldak, S. Jackowski, 2007, Journal of Biological Chemistry.

Phospholipid Biosynthesis Program Underlying Membrane Expansion during B-lymphocyte Differentiation*

P. Fagone, S. Jackowski, Jina Wang, 2007, Journal of Biological Chemistry.

Phosphatidylcholine as a metabolic cue for determining B cell fate and function.

R. Barrington, V. Solodushko, I. Aragon, 2014, Cellular immunology.

Phospholipids: "greasing the wheels" of humoral immunity.

J. W. Brewer, J. Brewer, 2013, Biochimica et biophysica acta.

The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.

K. Mori, J. W. Brewer, R. Barrington, 2012, Molecular immunology.

UPR-Mediated Membrane Biogenesis in B Cells

J. W. Brewer, S. Jackowski, J. Brewer, 2011, Biochemistry research international.

ATF6α induces XBP1-independent expansion of the endoplasmic reticulum

P. Fagone, R. Kaufman, J. W. Brewer, 2009, Journal of Cell Science.

CTP:Phosphocholine Cytidylyltransferase α Is Required for B-cell Proliferation and Class Switch Recombination*

P. Fagone, J. W. Brewer, S. Jackowski, 2009, Journal of Biological Chemistry.

Evidence That Marginal Zone B Cells Possess an Enhanced Secretory Apparatus and Exhibit Superior Secretory Activity1

J. W. Brewer, K. Gunn, J. Brewer, 2006, The Journal of Immunology.

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

K. Mori, S. Jackowski, R. Sriburi, 2004, The Journal of cell biology.

Activation of an Unfolded Protein Response during Differentiation of Antibody-secreting B Cells*

J. W. Brewer, Jennifer N Gass, Nicole M Gifford, 2002, The Journal of Biological Chemistry.

Interleukin-5 (IL-5) and IL-6 define two molecularly distinct pathways of B-cell differentiation

R. Wall, J. W. Brewer, T. Randall, 1993, Molecular and cellular biology.

Geldanamycin, an hsp90/GRP94‐binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathway

L. Hendershot, J. Brewer, B. Lawson, 1998, Journal of cellular physiology.

MicroRNA-30 c-2 * limits expression of proadaptive factor XBP 1 in the unfolded protein response

A. Byrd, I. Aragon, J. Brewer, 2012 .

Stressed-out B cells? Plasma-cell differentiation and the unfolded protein response.

R. Sriburi, Jennifer N Gass, K. Gunn, 2004, Trends in immunology.

Regulatory crosstalk within the mammalian unfolded protein response

J. W. Brewer, J. Brewer, 2014, Cellular and Molecular Life Sciences.

Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression

John Bechill, J. W. Brewer, S. Baker, 2008, Journal of Virology.

Late events in assembly determine the polymeric structure and biological activity of secretory IgM.

J. W. Brewer, R. Corley, J. Brewer, 1997, Molecular immunology.

Quality control in protein biogenesis: thiol-mediated retention monitors the redox state of proteins in the endoplasmic reticulum.

J. W. Brewer, R. Corley, J. Brewer, 1996, Journal of cell science.

The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells.

J. W. Brewer, R. Wek, Hao Jiang, 2008, Molecular immunology.

A role for the unfolded protein response in optimizing antibody secretion.

K. Mori, J. W. Brewer, Nicole M Gifford, 2004, Molecular immunology.

Intricately Regulated: A Cellular Toolbox for Fine-Tuning XBP1 Expression and Activity

J. W. Brewer, A. Byrd, J. Brewer, 2012, Cells.

Regulatory crosstalk within the mammalian unfolded protein response

J. Brewer, 2013, Cellular and Molecular Life Sciences.

XBP1

K. Mori, J. W. Brewer, S. Jackowski, 2004, The Journal of Cell Biology.

Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells.

J. W. Brewer, T. Randall, R. Corley, 1992, The Journal of biological chemistry.

IgM hexamers?

J. W. Brewer, R. Parkhouse, T. Randall, 1994, Immunology today.

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

K. Mori, S. Jackowski, R. Sriburi, 2004, The Journal of cell biology.

Niren Kapoor, Rafał Bartoszewski, D. Crossman, 2011 .