Xi‐Ming Sun

发表

Size-Dependent Increase in RNA Polymerase II Initiation Rates Mediates Gene Expression Scaling with Cell Size

V. Shahrezaei, S. Marguerat, D. Dormann, 2019, Current Biology.

Single-cell imaging and RNA sequencing reveal patterns of gene expression heterogeneity during fission yeast growth and adaptation

V. Shahrezaei, J. Bähler, S. Marguerat, 2019, Nature Microbiology.

Single-cell phenotyping and RNA sequencing reveal novel patterns of gene expression heterogeneity and regulation during growth and stress adaptation in a unicellular eukaryote

V. Shahrezaei, J. Bähler, S. Marguerat, 2018 .

Degradation of LDLR protein mediated by 'gain of function' PCSK9 mutants in normal and ARH cells.

Tommaso Fasano, A. Soutar, Xi-Ming Sun, 2009, Atherosclerosis.

Premature Senescence in Cells From Patients With Autosomal Recessive Hypercholesterolemia (ARH): Evidence for a Role for ARH in Mitosis

A. Soutar, J. Gil, J. Acosta, 2011, Arteriosclerosis, thrombosis, and vascular biology.

R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements

V. A. Tallada, J. Bähler, S. Marguerat, 2019, bioRxiv.

Size-Dependent Expression of the Fission Yeast Cdc13 Cyclin is Conferred by Translational Regulation

N. Rhind, S. Marguerat, M. Pickering, 2023, bioRxiv.

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

L. Steinmetz, S. Marguerat, S. Clauder-Münster, 2018, bioRxiv.

The Transmembrane Domain and PXXP Motifs of ApoE Receptor 2 Exclude It from Carrying out Clathrin-mediated Endocytosis*

A. Soutar, Xi-Ming Sun, Xi‐Ming Sun, 2003, Journal of Biological Chemistry.

Size-Dependent Expression of the Mitotic Activator Cdc 25 as a Mechanism of Size Control in Fission Yeast

Michael B. Mayhew, N. Rhind, D. Keifenheim, 2016 .

Size-Dependent Expression of the Mitotic Activator Cdc25 Suggests a Mechanism of Size Control in Fission Yeast

Michael B. Mayhew, N. Rhind, S. Marguerat, 2016, Current Biology.

Increased Secretion of Lipoproteins in Transgenic Mice Expressing Human D374Y PCSK9 Under Physiological Genetic Control

A. Soutar, Xi-Ming Sun, S. Waddington, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia.

David Wile, A. Soutar, R. Naoumova, 2005, Human molecular genetics.

Sorting Motifs in the Intracellular Domain of the Low Density Lipoprotein Receptor Interact with a Novel Domain of Sorting Nexin-17*

A. Soutar, J. Burden, Xi‐Ming Sun, 2004, Journal of Biological Chemistry.

Adaptor protein disabled-2 modulates low density lipoprotein receptor synthesis in fibroblasts from patients with autosomal recessive hypercholesterolaemia.

A. Soutar, Xi-Ming Sun, E. Eden, 2007, Human molecular genetics.

Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1.

A. Soutar, R. Naoumova, M. Themis, 2002, The Journal of clinical investigation.

Identification of recurrent and novel mutations in exon 4 of the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom.

V. Gudnason, S. Humphries, A. Soutar, 1993, Arteriosclerosis and Thrombosis A Journal of Vascular Biology.

Single-cell imaging and RNA sequencing reveal patterns of gene expression heterogeneity during fission yeast growth and adaptation

V. Shahrezaei, J. Bähler, S. Marguerat, 2019, Nature Microbiology.

Characterization of two new point mutations in the low density lipoprotein receptor genes of an English patient with homozygous familial hypercholesterolemia.

A. Soutar, J. Webb, B. Knight, 1992, Journal of lipid research.

Characterization of a novel cellular defect in patients with phenotypic homozygous familial hypercholesterolemia.

A. Soutar, M. Bourbon, R. Naoumova, 1999, The Journal of clinical investigation.

Characterization of mutations in the low density lipoprotein (LDL)-receptor gene in patients with homozygous familial hypercholesterolemia, and frequency of these mutations in FH patients in the United Kingdom.

A. Soutar, J. Webb, G. Thompson, 1996, Journal of lipid research.

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

L. Steinmetz, S. Marguerat, S. Clauder-Münster, 2018, bioRxiv.

Increased Secretion of Lipoproteins in Transgenic Mice Expressing Human D374Y PCSK9 Under Physiological Genetic Control

A. Soutar, S. Waddington, B. Herbert, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Fh-Souassi: a founder frameshift mutation in exon 10 of the LDL-receptor gene, associated with a mild phenotype in Tunisian families.

A. Soutar, V. Clavey, S. Lestavel, 2001, Atherosclerosis.

Effect of the StuI polymorphism in the LDL receptor gene (Ala 370 to Thr) on lipid levels in healthy individuals

V. Gudnason, S. Humphries, A. Soutar, 1995, Clinical genetics.

Phenotypic variation in heterozygous familial hypercholesterolemia: a comparison of Chinese patients with the same or similar mutations in the LDL receptor gene in China or Canada.

M. Hayden, A. Soutar, J. Frohlich, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Inheritance of two different alleles of the low‐density lipoprotein (LDL)‐receptor gene carrying the recurrent Pro664Leu mutation in a patient with homozygous familial hypercholesterolaemia

A. Soutar, M. Bourbon, X. Sun, 1999, Clinical genetics.

Characterization of deletions in the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom.

V. Gudnason, S. Humphries, A. Soutar, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements

V. A. Tallada, J. Bähler, S. Marguerat, 2021, PLoS genetics.

The molecular basis for apolipoprotein E-induced activation of nitric oxide synthase — Functional coupling of apoE receptor 2 to NOS III *

A. Soutar, D. Riddell, N. Chadwick, 1999 .

Premature Senescence in Cells From Patients With Autosomal Recessive Hypercholesterolemia (ARH): Evidence for a Role for ARH in Mitosis

A. Soutar, J. Gil, J. Acosta, 2011, Arteriosclerosis, Thrombosis and Vascular Biology.

Expression in vitro of alternatively spliced variants of the messenger RNA for human apolipoprotein E receptor-2 identified in human tissues by ribonuclease protection assays.

A. Soutar, X. Sun, Xi‐Ming Sun, 1999, European journal of biochemistry.