Jim Gamez

The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-alpha production with antitumor activity.

Lei Wu, P. Schafer, L. Corral, 2006, Cancer research.

Use of core modification in the discovery of CC214-2, an orally available, selective inhibitor of mTOR kinase.

D. Mortensen, J. Leisten, B. Whitefield, 2013, Bioorganic & medicinal chemistry letters.

Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization

P. Worland, Shuichan Xu, D. Mortensen, 2015, Molecular Cancer Therapeutics.

Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

Differential Effects of Iberdomide Versus Revlimid on Leukocyte Trafficking, Immune Activation and DLBCL Tumor Cell Killing

A. Shakya, P. Hagner, A. Ramsay, 2021, Blood.

Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization

P. Worland, Shuichan Xu, D. Mortensen, 2015, Molecular Cancer Therapeutics.