Qiang Yu

发表

4'-Alkoxyl substitution enhancing the anti-mitotic effect of 5-(3',4',5'-substituted)anilino-4-hydroxy-8-nitroquinazolines as a novel class of anti-microtubule agents.

Y. Long, Yi Jin, Wei Tian, 2006, Bioorganic & medicinal chemistry letters.

Chikusetsusaponin IVa Butyl Ester (CS-IVa-Be), a Novel IL6R Antagonist, Inhibits IL6/STAT3 Signaling Pathway and Induces Cancer Cell Apoptosis

Qiang Z Yu, Jie Yang, Xueting Cai, 2016, Molecular Cancer Therapeutics.

Inhibitory activities of Lignum Sappan extractives on growth and growth-related signaling of tumor cells.

Qiang Z Yu, Qing Zhang, Chunting Qi, 2014, Chinese journal of natural medicines.

Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells

Xiaoxiao Sun, Hui Guo, Xiaoxiao Sun, 2016, Oncotarget.

Receptor Tyrosine Kinase Phosphorylation Pattern–Based Multidrug Combination Is an Effective Approach for Personalized Cancer Treatment

Xiaoxiao Sun, Li He, Lei Yan, 2016, Molecular Cancer Therapeutics.

Apoptosis, autophagy, necroptosis, and cancer metastasis

Qiang Z Yu, Zuozhang Yang, Yongqing Xu, 2015, Molecular Cancer.

Synthetic derivatives of the natural product 13-amino 2-desoxy-4-epi-pulchellin inhibit STAT3 signaling and induce G2/M arrest and death of colon cancer cells.

Hui-Sheng Huang, Lihong Hu, Junxing Niu, 2019, Bioorganic & medicinal chemistry letters.

Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum.

Qiang Z Yu, Jiawei Liu, Qing Zhang, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

17-hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells.

S. Shen, Hongbing Wang, Yuan Gu, 2009, Cancer research.

Activation of necroptosis in multiple sclerosis.

Junying Yuan, Wen Zhou, Jiefei Geng, 2015, Cell reports.

Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine.

Qiang Z Yu, Y. Long, Ting Xue, 2008, Journal of medicinal chemistry.

Arctigenin alleviates ER stress via activating AMPK

Ji-Ming Ye, Yuan Gu, Xiaoxiao Sun, 2012, Acta Pharmacologica Sinica.

Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases

Qiang Z Yu, Minjia Tan, Lihong Hu, 2018, Molecules.

MicroRNAs in apoptosis, autophagy and necroptosis

Zuozhang Yang, Yongqing Xu, Yongbin Chen, 2015, Oncotarget.

Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment

Xiaoxiao Sun, Qiang Yu, Xiao-xiao Sun, 2015, Acta Pharmacologica Sinica.

Selective Induction of Tumor Cell Apoptosis by a Novel P450-mediated Reactive Oxygen Species (ROS) Inducer Methyl 3-(4-Nitrophenyl) Propiolate*

Ying Wang, Yi Jin, S. Shen, 2013, The Journal of Biological Chemistry.

Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis

Junying Yuan, B. Shan, D. E. Christofferson, 2018, Proceedings of the National Academy of Sciences.

Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth

Qiang Z Yu, Li-Hua Xu, Xing Zhang, 2010, Molecular Cancer.

Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas

Qing Zhang, Chunting Qi, Yu Chen, 2019, BMC Cancer.

Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy

Y. Li, Junying Yuan, S. Shen, 2009, The Journal of cell biology.

PDE3A inhibitor anagrelide activates death signaling pathway genes and synergizes with cell death-inducing cytokines to selectively inhibit cancer cell growth.

R. An, Qing Zhang, Jing He, 2019, American journal of cancer research.

A natural compound derivative P-13 inhibits STAT3 signaling by covalently inhibiting Janus kinase 2

Fei Wang, Hui-Sheng Huang, Lihong Hu, 2018, Investigational New Drugs.

3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells

Sheng Yao, Qiang Z Yu, Y. Ye, 2019, Acta Pharmacologica Sinica.

A Novel Synthetic Analog of 5, 8-Disubstituted Quinazolines Blocks Mitosis and Induces Apoptosis of Tumor Cells by Inhibiting Microtubule Polymerization

Li He, Qiang Z Yu, Midan Ai, 2010, PloS one.

Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells

Yuan Gu, Xiaoxiao Sun, Hao-hao Zhang, 2015, Acta Pharmacologica Sinica.

Comprehensive metabolomics expands precision medicine for triple-negative breast cancer

Fan Yang, Xin Hu, F. Bertucci, 2022, Cell Research.

Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death

Junying Yuan, Xiaoxiao Sun, Qiang Z Yu, 2018, Cell Death & Disease.

Eriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3

Li He, P. Cao, Qiang Yu, 2015, PloS one.

Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore

Ge Liu, Chaomin Sun, Linlin Zhang, 2017, Oncotarget.

Triptolide (TPL) Inhibits Global Transcription by Inducing Proteasome-Dependent Degradation of RNA Polymerase II (Pol II)

Li He, Qiang Z Yu, Ying Wang, 2011, PloS one.

Discovery of Novel 2‐N‐Aryl‐Substituted Benzenesulfonamidoacetamides: Orally Bioavailable Tubulin Polymerization Inhibitors with Marked Antitumor Activities

Long Yu, Y. Long, D. Xue, 2012, ChemMedChem.

A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule

Xiao-min Luo, Y. Wang, Shan Kuang, 2012, Acta Pharmacologica Sinica.