Kun-Liang Guan

发表

Identification of essential functional elements of pls!nk4c

S. J. Noh, Y. Lj, Y. Xiong, 1998 .

Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma.

Karl-Heinz Krause, Paul S Mischel, Kun-Liang Guan, 2017, Cancer cell.

A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening

Bin Li, Bing Ren, Lenka Maliskova, 2016, Genome research.

Glutathione-S-transferase (GST)-fusion based assays for studying protein-protein interactions.

Kun-Liang Guan, H. Vikis, K. Guan, 2015, Methods in molecular biology.

Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α

Kun-Liang Guan, Wei Xu, Wei Yu, 2009, Science.

Structural insights into the YAP and TEAD complex.

Fei Chen, Ze Li, Bin Zhao, 2010, Genes & development.

Hippo signaling at a glance

Li Li, Bin Zhao, Kun-Liang Guan, 2010, Journal of Cell Science.

IDH1 and IDH2 Mutations in Tumorigenesis: Mechanistic Insights and Clinical Perspectives

Hui Yang, Kun-Liang Guan, Yue Xiong, 2012, Clinical Cancer Research.

Dysregulation of the TSC-mTOR pathway in human disease

Kun-Liang Guan, K. Inoki, K. Guan, 2004, Nature Genetics.

Wildtype Kras2 can inhibit lung carcinogenesis in mice

Ming You, Kun-Liang Guan, Robert C. Sills, 2001, Nature Genetics.

Autophagy regulation by nutrient signaling

Kun-Liang Guan, K. Guan, R. Russell, 2013, Cell Research.

Isolation and Characterization of a Novel Dual Specific Phosphatase, HVH2, Which Selectively Dephosphorylates the Mitogen-activated Protein Kinase (*)

Kun-Liang Guan, K. Guan, E. Butch, 1995, The Journal of Biological Chemistry.

Nutrient sensing, metabolism, and cell growth control.

Kun-Liang Guan, Yue Xiong, Y. Xiong, 2013, Molecular cell.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Kinase Suppressor of Ras Forms a Multiprotein Signaling Complex and Modulates MEK Localization

Kun-Liang Guan, Jeeyong Lee, Min Han, 1999, Molecular and Cellular Biology.

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.

Kun-Liang Guan, Hyun Woo Park, Susan S. Taylor, 2013, Genes & development.

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

Xiang-Dong Fu, Bin Zhao, Kun-Liang Guan, 2012, Cell.

PTEN acetylation modulates its interaction with PDZ domain.

Bin Zhao, Kun-Liang Guan, K. Inoki, 2008, Cancer research.

The Hippo pathway in organ development, homeostasis, and regeneration.

Kun-Liang Guan, K. Guan, Vivian X. Fu, 2017, Current opinion in cell biology.

The hippo pathway in heart development, regeneration, and diseases.

Li Li, Bin Zhao, Kun-Liang Guan, 2015, Circulation research.

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

Li Li, Xiaomu Wei, Joungmok Kim, 2007, Genes & development.

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version.

Li Li, Bin Zhao, Kun-Liang Guan, 2010, Genes & development.

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

Bin Wang, Jing Liu, Yi Zhang, 2011, Cancer cell.

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

Guo-Ping Zhao, Yufeng Yao, Chen Yang, 2010, Science.

Alternative Wnt Signaling Activates YAP/TAZ

Young Chul Kim, Kun-Liang Guan, Hyun Woo Park, 2015, Cell.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

Bin Zhao, Kun-Liang Guan, K. Guan, 2015, Cell.

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation.

Joungmok Kim, Bin Zhao, Kun-Liang Guan, 2010, Genes & development.

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

Bin Zhao, Kun-Liang Guan, K. Guan, 2011, Nature Cell Biology.

The emerging roles of YAP and TAZ in cancer

Kun-Liang Guan, K. Guan, C. G. Hansen, 2015, Nature Reviews Cancer.

Mechanisms of regulating the Raf kinase family.

Kun-Liang Guan, H. Vikis, K. Guan, 2003, Cellular signalling.

TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Ming You, Kun-Liang Guan, Bart O. Williams, 2006, Cell.

Mechanisms of Hippo pathway regulation

Kun-Liang Guan, K. Guan, Z. Meng, 2016, Genes & development.

A Critical Role for Rictor in T Lymphopoiesis

Kun-Liang Guan, Yang Liu, Fei Tang, 2012, The Journal of Immunology.

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.

Hui Yang, Ying Liu, Wei Xu, 2012, Genes & development.

Regulation of intermediary metabolism by protein acetylation.

Kun-Liang Guan, Yue Xiong, Y. Xiong, 2011, Trends in biochemical sciences.

Glutathione-S-transferase-fusion based assays for studying protein-protein interactions.

Kun-Liang Guan, H. Vikis, K. Guan, 2004, Methods in molecular biology.