Patrick Augustijns

发表

Erratum: Hens, B.; et al. Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola® on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b). Pharmaceutics, 2020, 12, 566

Bart Hens, Marival Bermejo, Patrick Augustijns, 2020, Pharmaceutics.

Comparison of the estimation of concentration-time profiles using GastroPlus simulations software with experimental data: Caco-2 versus in silico permeability inputs

Patrick Augustijns, M. Perez de la Cruz Moreno, M. Oth, 2003 .

Development and validation of a novel generic UPLC/MS/MS method for high throughput analysis drug discovery

Patrick Augustijns, A. Melis, J. Mensch, 2007 .

Use of the gastro-plus simulations software as a predictive tool for concentration-time profiles in rats using Caco-2 and in silico permeability inputs

Patrick Augustijns, M. Perez de la Cruz Moreno, M. Oth, 2003 .

Evaluation and implementation of a novel generic UPLC/MS/MS method for high throughput analysis in Drug Discovery

Patrick Augustijns, A. Melis, J. Mensch, 2007 .

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

Talia Flanagan, Clive G. Wilson, Mai Anh Nguyen, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Combined use of ordered mesoporous silica and precipitation inhibitors for improved oral absorption of the poorly soluble weak base itraconazole.

Patrick Augustijns, Jan Van Humbeeck, J. van Humbeeck, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole.

Amitava Mitra, Bart Hens, Bo Liu, 2017, Molecular pharmaceutics.

A screening study of surface stabilization during the production of drug nanocrystals.

Ludo Froyen, Patrick Augustijns, Bernard Van Eerdenbrugh, 2009, Journal of pharmaceutical sciences.

In vivo, in vitro and in silico methods for small molecule transfer across the BBB.

Julen Oyarzabal, Patrick Augustijns, Claire Mackie, 2009, Journal of pharmaceutical sciences.

Solubility increases associated with crystalline drug nanoparticles: methodologies and significance.

Jan Van Humbeeck, Ludo Froyen, Patrick Augustijns, 2010, Molecular pharmaceutics.

Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products.

Patrick Augustijns, Bernard Van Eerdenbrugh, P. Augustijns, 2008, International journal of pharmaceutics.

Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials.

Patrick Augustijns, Jan Van Humbeeck, J. van Humbeeck, 2007, Chemical communications.

Excipient-mediated supersaturation stabilization in human intestinal fluids.

Patrick Augustijns, Jan Bevernage, Jan Tack, 2011, Molecular pharmaceutics.

Exploring gastrointestinal variables affecting drug and formulation behavior: Methodologies, challenges and opportunities.

Roelof J Bennink, Clive G. Wilson, Bart Hens, 2017, International journal of pharmaceutics.

Validation of Dissolution Testing with Biorelevant Media: An OrBiTo Study.

Patrick Augustijns, René Holm, Paul Hutchins, 2017, Molecular pharmaceutics.

Ordered mesoporous silica material SBA-15: a broad-spectrum formulation platform for poorly soluble drugs.

Patrick Augustijns, Jan Vermant, Johan Martens, 2009, Journal of pharmaceutical sciences.

A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption.

Bart Hens, Patrick Augustijns, James Butler, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.

Ivo Que, Joke Bouwstra, Patrick Augustijns, 2010, Vaccine.

Interplay of supersaturation and solubilization: Lack of correlation between concentration-based supersaturation measurements and membrane transport rates in simulated and aspirated human fluids.

Patrick Augustijns, Lynne S. Taylor, P. Augustijns, 2019, Molecular pharmaceutics.

The conflict between in vitro release studies in human biorelevant media and the in vivo exposure in rats of the lipophilic compound fenofibrate.

Patrick Augustijns, Jan Vermant, Johan Martens, 2011, International journal of pharmaceutics.

Incomplete desorption of liquid excipients reduces the in vitro and in vivo performance of self-emulsifying drug delivery systems solidified by adsorption onto an inorganic mesoporous carrier.

Patrick Augustijns, Hywel D Williams, Christopher J H Porter, 2012, Molecular pharmaceutics.

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1

Zhiwei Ye, Patrick Augustijns, Bruno Stieger, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Physico-chemical characterization of solid dispersions of temazepam with polyethylene glycol 6000 and PVP K30

Patrick Augustijns, Norbert Blaton, P. Augustijns, 1998 .

Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica.

Patrick Augustijns, Jan Van Humbeeck, J. van Humbeeck, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica.

Patrick Augustijns, Jan Van Humbeeck, J. van Humbeeck, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The artificial membrane insert system as predictive tool for formulation performance evaluation.

Patrick Augustijns, P. Augustijns, J. Brouwers, 2018, International journal of pharmaceutics.

In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration

Anette Müllertz, Filippos Kesisoglou, Christos Reppas, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Preventing release in the acidic environment of the stomach via occlusion in ordered mesoporous silica enhances the absorption of poorly soluble weakly acidic drugs.

Patrick Augustijns, Jan Van Humbeeck, J. van Humbeeck, 2011, Journal of pharmaceutical sciences.

Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?

Patrick Augustijns, M. Brewster, P. Augustijns, 2009, Journal of pharmaceutical sciences.

Supersaturation and Precipitation of Posaconazole Upon Entry in the Upper Small Intestine in Humans.

Bart Hens, Maura Corsetti, Patrick Augustijns, 2015, Journal of pharmaceutical sciences.

In vitro models for the prediction of in vivo performance of oral dosage forms.

Anette Müllertz, Patrick Augustijns, Bertil Abrahamsson, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Downscaling Drug Nanosuspension Production: Processing Aspects and Physicochemical Characterization

Jan Van Humbeeck, Ludo Froyen, Patrick Augustijns, 2009, AAPS PharmSciTech.

Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1.

Patrick Augustijns, Paul J Lewi, Jurgen Joossens, 2014, Antiviral research.

Thermal characterization of the antiviral drug UC-781 and stability of its glass

Lieve Naesens, Jan Balzarini, Patrick Augustijns, 2001 .

Characterization of fasted‐state human intestinal fluids collected from duodenum and jejunum

Patrick Augustijns, Jan Tack, Jennifer Dressman, 2006, The Journal of pharmacy and pharmacology.

Alternative matrix formers for nanosuspension solidification: Dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion.

Ludo Froyen, Patrick Augustijns, Bernard Van Eerdenbrugh, 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: a case study with amprenavir.

Patrick Augustijns, Jan Tack, F. Lammert, 2006, Journal of pharmaceutical sciences.

Investigation of thermal properties of glassy itraconazole: identification of a monotropic mesophase

Koen Binnemans, Patrick Augustijns, Geert Verreck, 2001 .

Itraconazole/TPGS/Aerosil200 solid dispersions: characterization, physical stability and in vivo performance.

Ludo Froyen, Patrick Augustijns, Bernard Van Eerdenbrugh, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.