J. Mangas-Sánchez

发表

Asymmetric chemoenzymatic synthesis of miconazole and econazole enantiomers. The importance of chirality in their biological evaluation.

E. Busto, V. Gotor‐Fernández, F. Malpartida, 2011, The Journal of organic chemistry.

Enantiopure 3-methyl-3,4-dihydroisocoumarins and 3-methyl-1,2,3,4-tetrahydroisoquinolines via chemoenzymatic asymmetric transformations

E. Busto, V. Gotor‐Fernández, V. Gotor, 2012 .

Asymmetric (Transfer) Hydrogenation of Imines

C. Claver, I. Peñafiel, J. Mangas-Sánchez, 2021 .

Straightforward synthesis of enantiopure 2,3-dihydrobenzofurans by a sequential stereoselective biotransformation and chemical intramolecular cyclization.

E. Busto, V. Gotor‐Fernández, V. Gotor, 2010, Organic letters.

One-pot synthesis of enantiopure 3,4-dihydroisocoumarins through dynamic reductive kinetic resolution processes.

E. Busto, V. Gotor‐Fernández, V. Gotor, 2013, Organic letters.

Biocatalytic Synthesis of Chiral Amines Using Oxidoreductases

N. Turner, S. Cosgrove, J. Mangas-Sanchez, 2021 .

Chemoenzymatic Deracemization of Secondary Alcohols by using a TEMPO–Iodine–Alcohol Dehydrogenase System

I. Lavandera, V. Gotor‐Fernández, V. Gotor, 2015 .

Application of Engineered Biocatalysts for the Synthesis of Active Pharmaceutical Ingredients (APIs)

S. Cosgrove, N. J. Turner, J. Mangas-Sánchez, 2021, Protein Engineering.

Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades.

Nicholas J Turner, N. Turner, Sasha R. Derrington, 2019, Journal of the American Chemical Society.

Influence of the Nucleophile on the Candida antarctica Lipase B‐Catalysed Resolution of a Chiral Acyl Donor

V. Gotor‐Fernández, V. Gotor, J. Mangas-Sanchez, 2009, Chembiochem : a European journal of chemical biology.

Stereoselective Three‐Step One‐Pot Cascade Combining Amino‐ and Biocatalysis to Access Chiral γ‐Nitro Alcohols

Raquel P. Herrera, J. Mangas-Sánchez, Christian Ascaso-Alegre, 2022, Angewandte Chemie.

NAD(P)H‐Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application

N. Turner, G. Grogan, Mahima Sharma, 2017, Advanced synthesis & catalysis.

Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination

Roger M. Howard, R. Kumar, N. Turner, 2018 .

Highly stereoselective chemoenzymatic synthesis of the 3H-isobenzofuran skeleton. Access to enantiopure 3-methylphthalides.

E. Busto, V. Gotor‐Fernández, V. Gotor, 2012, Organic letters.

A reductive aminase from Aspergillus oryzae

Mahima Sharma, N. Turner, G. Grogan, 2017, Nature Chemistry.

A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases

N. Turner, G. Grogan, Mahima Sharma, 2018, ACS Catalysis.

Direct Alkylation of Amines with Primary and Secondary Alcohols through Biocatalytic Hydrogen Borrowing.

Nicholas J Turner, M. Thompson, N. Turner, 2017, Angewandte Chemie.

Chemoenzymatic synthesis of rivastigmine based on lipase-catalyzed processes.

E. Busto, V. Gotor‐Fernández, V. Gotor, 2009, The Journal of organic chemistry.

Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines.

Nicholas J Turner, Rajesh Kumar, Robert Crook, 2017, Angewandte Chemie.

Imine reductases (IREDs).

Nicholas J Turner, Mahima Sharma, N. Turner, 2017, Current opinion in chemical biology.

One-pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles.

Roger M. Howard, F. Parmeggiani, N. Turner, 2019, Journal of the American Chemical Society.

Discovery of a new metal and NAD+-dependent formate dehydrogenase from Clostridium ljungdahlii

N. Turner, W. Birmingham, B. Binay, 2018, Preparative biochemistry & biotechnology.

Engineered formate dehydrogenase from Chaetomium thermophilum, a promising enzymatic solution for biotechnical CO2 fixation

O. Turunen, J. Valjakka, N. Turner, 2020, Biotechnology Letters.

Expanding the synthetic scope of biocatalysis by enzyme discovery and protein engineering

N. Turner, J. Marshall, J. Mangas-Sánchez, 2021 .

Kinetic Resolution and Deracemization of Racemic Amines Using a Reductive Aminase

M. Thompson, N. Turner, Rachel S. Heath, 2018 .

A biocatalytic cascade for the amination of unfunctionalised cycloalkanes.

M. Thompson, N. Turner, Michele Tavanti, 2017, Organic & biomolecular chemistry.

Imine Reductases, Reductive Aminases, and Amine Oxidases for the Synthesis of Chiral Amines: Discovery, Characterization, and Synthetic Applications.

N. Turner, Rachel S. Heath, S. Cosgrove, 2018, Methods in enzymology.

Experimental Characterization Techniques of Hybrid Catalysts

E. Busto, J. Mangas-Sanchez, J. Mangas-Sánchez, 2018 .

Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination

Peiyuan Yao, S. Charnock, N. Turner, 2020, Nature Chemistry.

Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases†

N. Turner, G. Grogan, Mahima Sharma, 2020, Chemical science.

Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships

N. Turner, J. Galman, Ahir Pushpanath, 2020, Science Advances.

Highly efficient enzymatic biodiesel production promoted by particle-induced emulsification

P. Adlercreutz, J. Mangas-Sánchez, 2015, Biotechnology for Biofuels.

New Trends and Future Opportunities in the Enzymatic Formation of C−C, C−N, and C−O bonds

N. Turner, J. Marshall, Jack J. Sangster, 2021, Chembiochem : a European journal of chemical biology.

Dynamic Reductive Kinetic Resolution of Benzyl Ketones using Alcohol Dehydrogenases and Anion Exchange Resins

E. Busto, V. Gotor‐Fernández, V. Gotor, 2016 .

Dynamic Reductive Kinetic Resolution of Benzyl Ketones Using Alcohol Dehydrogenases and Anion Exchange Resins.

E. Busto, V. Gotor‐Fernández, V. Gotor, 2016 .

Enantioselective Synthesis of Chiral Vicinal Amino Alcohols Using Amine Dehydrogenases

Jian‐He Xu, M. Thompson, N. Turner, 2019, ACS Catalysis.

Cascade Processes Merging Chemical and Enzyme Catalysis

J. Mangas-Sánchez, Christian Ascaso-Alegre, 2022, Synlett.

A generic platform for the immobilisation of engineered biocatalysts

Nicholas J. Turner, Paul N. Devine, Matthew D. Truppo, 2019, Tetrahedron.

Direct Alkylation of Amines with Primary and Secondary Alcohols through Biocatalytic Hydrogen Borrowing.

M. Thompson, N. Turner, Godwin A. Aleku, 2017, Angewandte Chemie.

One-Pot Chemoenzymatic Cascade for the Enantioselective C(1)-Allylation of Tetrahydroisoquinolines

N. Turner, S. Cosgrove, Jack J. Sangster, 2023, Journal of the American Chemical Society.