Lihuai Qin

Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells.

Xin Hu, Jingkang Shen, Z. Miao, 2021, Genomics.

Potent and Selective Mitogen-Activated Protein Kinase Kinase 1/2 (MEK1/2) Heterobifunctional Small-molecule Degraders.

Xian Chen, Ling Xie, Li Wang, 2020, Journal of medicinal chemistry.

A promising chemical series of positive allosteric modulators of the μ-opioid receptor that enhance the antinociceptive efficacy of opioids but not their adverse effects

B. Roth, T. Che, M. Filizola, 2021, Neuropharmacology.

Structure-based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors.

Z. Miao, Jian Li, B. Xiong, 2019, Journal of medicinal chemistry.

Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy

G. Wang, H. Kaniskan, M. Kabir, 2022, bioRxiv.

A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression

Ling Xie, H. Kaniskan, Brandon Dale, 2024, Science advances.

Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader.

Jian Jin, Lihuai Qin, Yan Xiong, 2024, Journal of medicinal chemistry.