Stefan von Berg

发表

Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease*

Britt-Marie Swahn, Bart Ploeger, Tjerk Bueters, 2012, The Journal of Biological Chemistry.

New aminoimidazoles as β-secretase (BACE-1) inhibitors showing amyloid-β (Aβ) lowering in brain.

S. Eketjäll, B. Swahn, K. Kolmodin, 2012, Journal of medicinal chemistry.

Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.

Sven Hellberg, Stefan Berg, S. Hellberg, 2012, Journal of medicinal chemistry.

Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2.

Yafeng Xue, F. Narjes, Marie Brännström, 2019, ACS medicinal chemistry letters.

A Phenotypic Screening Approach Using Human Treg Cells Identified Regulators of Forkhead Box p3 Expression.

U. Gehrmann, Elke Ericson, Mei Ding, 2019, ACS chemical biology.

Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design.

Yafeng Xue, F. Narjes, Elisabeth Bäck, 2018, Journal of medicinal chemistry.

Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ

Yafeng Xue, F. Narjes, A. Aagaard, 2016, ChemMedChem.

AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2.

R. Pehrson, Yafeng Xue, F. Narjes, 2021, Journal of medicinal chemistry.

Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides.

Britt-Marie Swahn, Johan Lindström, Stefan Berg, 2012, Journal of medicinal chemistry.

Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring

J. Holenz, J. Malmquist, B. Swahn, 2013, Drug Metabolism and Disposition.

Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ

Yafeng Xue, F. Narjes, A. Aagaard, 2016, ChemMedChem.

Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design.

Yafeng Xue, F. Narjes, Elisabeth Bäck, 2018, Journal of medicinal chemistry.

Synthesis of Highly Enantioenriched Compounds via Iron Mediated Allylic Substitutions

D. Enders, B. Jandeleit, Stefan von Berg, 1997 .