Karol Szczepanek

发表

Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727*

P. Dent, K. Valerie, A. Yacoub, 2013, The Journal of Biological Chemistry.

Function of Mitochondrial Stat3 in Cellular Respiration

P. Fawcett, Xin-Yuan Fu, D. Baker, 2009, Science.

Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia.

G. Collet, K. Węglarczyk, C. Kieda, 2016, Cancer letters.

Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species*

Marta Derecka, J. Dulak, Qun Chen, 2011, The Journal of Biological Chemistry.

Integrated analyses of murine breast cancer models reveal critical parallels with human disease

K. Hunter, E. Andrechek, K. Szczepanek, 2019, Nature Communications.

Integrated sequence and gene expression analysis of mouse models of breast cancer reveals critical events with human parallels

K. Hunter, E. Andrechek, Christina Ross, 2018, bioRxiv.

Multi-tasking: nuclear transcription factors with novel roles in the mitochondria.

Karol Szczepanek, Edward J Lesnefsky, E. Lesnefsky, 2012, Trends in cell biology.

The role of Tyk2 in regulation of breast cancer growth.

D. Conrad, H. Bear, S. Grant, 2011, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

The genomic landscape of metastasis in treatment-naïve breast cancer models

Howard H. Yang, K. Hunter, Christina Ross, 2019, bioRxiv.

Acquired deficiency of tafazzin in the adult heart: Impact on mitochondrial function and response to cardiac injury.

J. Allegood, Qun Chen, E. Lesnefsky, 2016, Biochimica et biophysica acta.

Metastasis-Specific Gene Expression in Autochthonous and Allograft Mouse Mammary Tumor Models: Stratification and Identification of Targetable Signatures

Maxwell P. Lee, Howard H. Yang, K. Hunter, 2019, Molecular Cancer Research.

Cytoprotection by the modulation of mitochondrial electron transport chain: the emerging role of mitochondrial STAT3.

Qun Chen, E. Lesnefsky, A. Larner, 2012, Mitochondrion.

A deficiency of apoptosis inducing factor (AIF) in Harlequin mouse heart mitochondria paradoxically reduces ROS generation during ischemia-reperfusion

Qun Chen, E. Lesnefsky, K. Szczepanek, 2014, Front. Physiol..

Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury.

C. Baumgarten, E. Bowler, Qun Chen, 2014, American journal of physiology. Cell physiology.

Cardioprotection by modulation of mitochondrial respiration during ischemia-reperfusion: role of apoptosis-inducing factor.

Qun Chen, E. Lesnefsky, Ying Hu, 2013, Biochemical and biophysical research communications.

Electron flow into cytochrome c coupled with reactive oxygen species from the electron transport chain converts cytochrome c to a cardiolipin peroxidase: role during ischemia-reperfusion.

D. C. Simpson, J. Allegood, S. Gronert, 2014, Biochimica et biophysica acta.

Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension

J. Bigbee, C. D. dos Remedios, L. Farkas, 2013, Circulation. Heart failure.

Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: role of complex I inhibition vs. depolarization of inner mitochondrial membrane.

E. Bowler, Qun Chen, E. Lesnefsky, 2013, Biochimica et biophysica acta.

Function of Mitochondrial Stat 3 in Cellular Respiration

P. Fawcett, Xin-Yuan Fu, D. Baker, 2022 .

The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes

T. Harris, C. Croniger, Marta Derecka, 2015, PloS one.

Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity.

A. Russell, K. Rajewsky, P. Seale, 2012, Cell metabolism.

Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury

Qun Chen, E. Lesnefsky, K. Szczepanek, 2015, Basic Research in Cardiology.

Targeting metastatic breast cancer: problems and potential.

K. Hunter, Sarah K Deasy, Karol Szczepanek, 2015, F1000 faculty reviews.

Differential binding of hyaluronan on the surface of tissue-specific endothelial cell lines.

C. Kieda, K. Szczepanek, J. Cichy, 2008, Acta biochimica Polonica.

Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations

B. Aryal, D. Verthelyi, Melissa A. Pegues, 2021, Pharmaceutical Research.

Targeting metastatic breast cancer: problems and potential.

K. Hunter, Karol Szczepanek, Sarah K. Deasy, 2015, F1000 faculty reviews.

Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury.

C. Baumgarten, E. Bowler, Qun Chen, 2014, American journal of physiology. Cell physiology.

247 : Stat1 inhibits mitochondrial biogenesis

Marta Derecka, E. Lesnefsky, A. Larner, 2013 .

Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells

T. Harris, Marta Derecka, B. Strobl, 2016, Endocrinology.

The role of Tyk2 in regulation of breast cancer growth.

D. Conrad, H. Bear, S. Grant, 2011, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.