Adel Chergui

发表

Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors

Frank R. Fronczek, Yves Pommier, Junko Murai, 2014, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of New Carbohydrate-Substituted Indenoisoquinoline Topoisomerase I Inhibitors and Improved Syntheses of the Experimental Anticancer Agents Indotecan (LMP400) and Indimitecan (LMP776)

Y. Pommier, C. Marchand, M. Cushman, 2014, Journal of medicinal chemistry.

5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl-DNA phosphodiesterase I.

Y. Pommier, F. Chen, Y. Sham, 2012, Journal of medicinal chemistry.

Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform.

Y. Pommier, Ruili Huang, A. Jadhav, 2014, DNA repair.

Synthesis and biological evaluation of the first dual tyrosyl-DNA phosphodiesterase I (Tdp1)-topoisomerase I (Top1) inhibitors.

Y. Pommier, A. Stephen, R. Fisher, 2012, Journal of medicinal chemistry.

Synthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1).

Yves Pommier, Keli Agama, Martin Conda-Sheridan, 2013, Journal of medicinal chemistry.

Biochemical Assays for the Discovery of TDP1 Inhibitors

Y. Pommier, W. L. Jorgensen, A. Jadhav, 2014, Molecular Cancer Therapeutics.

Models and Technologies Biochemical Assays for the Discovery of TDP 1 Inhibitors

Y. Pommier, W. L. Jorgensen, A. Jadhav, 2014 .

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

Jason R. Evans, Y. Pommier, E. Goncharova, 2017, SLAS discovery : advancing life sciences R & D.

Immunotherapy in Acute Leukemias: Past Success Paves the Way for Future Progress

J. Reagan, Adel Chergui, 2023, Cancers.