R. Létienne

发表

Discovery of novel protease activated receptors 1 antagonists with potent antithrombotic activity in vivo.

D. Cussac, L. de Vries, C. Horn, 2009, Journal of medicinal chemistry.

Protease-activated receptor 1 antagonists prevent platelet aggregation and adhesion without affecting thrombin time.

A. Bocquet, R. Létienne, B. Le Grand, 2010, European journal of pharmacology.

Short‐term haemodynamic variability in the conscious areflexic rat

C. Julien, C. Cerutti, R. Létienne, 1998, The Journal of physiology.

Soman‐induced hypertension in conscious rats is mediated by prolonged central muscarinic stimulation

C. Julien, G. Lallement, D. Baubichon, 1999, Fundamental & clinical pharmacology.

F 16915 prevents heart failure-induced atrial fibrillation: a promising new drug as upstream therapy

S. Nattel, P. Legrand, S. Hatem, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Evidence that ranolazine behaves as a weak β1- and β2-adrenoceptor antagonist in the rat cardiovascular system

G. John, R. Létienne, B. Vié, 2001, Naunyn-Schmiedeberg's Archives of Pharmacology.

KC 12291: an atypical sodium channel blocker with myocardial antiischemic properties.

F. Colpaert, A. Coulombe, J. Patoiseau, 2006, Cardiovascular drug reviews.

Effects of SM-20550 Against Myocardial Infarction-induced Arrhythmias, Late Infarct Expansion, and Left Ventricular Dysfunction

N. Grosjean, B. Grand, R. Létienne, 2007, Journal of cardiovascular pharmacology.

Pharmacological characterisation of sodium channels in sinoatrial node pacemaking in the rat heart.

R. Létienne, B. Vié, B. Le Grand, 2006, European journal of pharmacology.

Cardioprotection of cariporide evaluated by plasma myoglobin and troponin I in myocardial infarction in pigs

A. Degryse, B. Grand, G. John, 2006, Fundamental & clinical pharmacology.

F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models

B. Vacher, B. Le Grand, C. Pignier, 2009, British journal of pharmacology.

CHARACTERIZATION OF A MAJOR SLOW OSCILLATION IN THE MESENTERIC CIRCULATION OF CONSCIOUS RATS

C. Julien, R. Létienne, C. Barrés, 1998, Clinical and experimental pharmacology & physiology.

Donitriptan Decreases Jugular Venous Oxygen Saturation in Rats in the Absence of Cranial Vasoconstriction: An Overlooked Mechanism of Antimigraine Action?

J. Blanchet, G. John, B. Le Grand, 2005, Journal of Pharmacology and Experimental Therapeutics.

Antithrombotic activity of F 16618, a new PAR1 antagonist evaluated in extracorporeal arterio-venous shunt in the rat.

R. Létienne, B. Le Grand, F. Nadal-Wollbold, 2010, Biochemical pharmacology.

PAR1 antagonist mediated antithrombotic activity in extracorporeal arterio-venous shunt in the rat.

A. Bocquet, R. Létienne, B. Le Grand, 2010, Thrombosis research.

Donitriptan Selectively Decreases Jugular Venous Oxygen Saturation in the Anesthetized Pig: Further Insights into Its Mechanism of Action Relevant to Headache Relief

F. Colpaert, G. John, B. Le Grand, 2003, Journal of Pharmacology and Experimental Therapeutics.

Na+ currents in cardioprotection: better to be late.

F. Colpaert, B. Vacher, B. Le Grand, 2009, Journal of medicinal chemistry.

Sodium late current blockers in ischemia reperfusion: is the bullet magic?

B. Vacher, R. Létienne, B. Le Grand, 2008, Journal of medicinal chemistry.

Antiplatelet and antithrombotic effect of F 16618, a new thrombin proteinase‐activated receptor‐1 (PAR1) antagonist

T. Mirault, P. Gaussem, F. Grelac, 2012, British journal of pharmacology.

Protease-Activated Receptor-1 Antagonist F 16618 Reduces Arterial Restenosis by Down-Regulation of Tumor Necrosis Factor α and Matrix Metalloproteinase 7 Expression, Migration, and Proliferation of Vascular Smooth Muscle Cells

S. Hatem, A. Lompré, M. David-Dufilho, 2011, Journal of Pharmacology and Experimental Therapeutics.

Effects of a new PAR1 antagonist, F 16618, on smooth muscle cell contraction.

L. de Vries, A. Bocquet, B. Le Grand, 2009, European journal of pharmacology.

F 16915 prevents heart failure-induced atrial fibrillation: a promising new drug as upstream therapy

S. Nattel, P. Legrand, S. Hatem, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Investigation of the Effects of Naratriptan, Rizatriptan, and Sumatriptan on Jugular Venous Oxygen Saturation in Anesthetized Pigs: Implications for Their Mechanism of Acute Antimigraine Action

G. John, R. Létienne, Y. Verscheure, 2003, Journal of Pharmacology and Experimental Therapeutics.

3-(R)-[3-(2-Methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine Bromhydrate (F 15845) Prevents Ischemia-Induced Heart Remodeling by Reduction of the Intracellular Na+ Overload

Monique Bernard, D. Feuvray, B. Vacher, 2009, Journal of Pharmacology and Experimental Therapeutics.