Qian Chai

发表

Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and beta-secretase.

Wei Wang, Jingkang Shen, Xin Wang, 2009, Bioorganic & medicinal chemistry.

ASSEMBLY AND DEGRAD ATION OF A TRIMERIC MEMBRANE PR OTEIN ACRB

Qian Chai, 2016 .

ASSEMBLY AND DEGRADATION OF A TRIMERIC MEMBRANE PROTEIN ACRB

Q. Chai, Qian Chai, 2016 .

Alternative NF‐κB signaling regulates mTEC differentiation from podoplanin‐expressing precursors in the cortico‐medullary junction

B. Becher, A. Waisman, R. Maier, 2015, European journal of immunology.

Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B

P. Zhu, Wenhui Li, Xiyun Yan, 2020, Nature Nanotechnology.

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses

B. Ludewig, H. Macdonald, F. Tacchini-Cottier, 2014, The Journal of experimental medicine.

Epithelial LTβR signaling controls the population size of the progenitors of medullary thymic epithelial cells in neonatal mice

C. Jin, Mingzhao Zhu, Q. Chai, 2017, Scientific Reports.

Inhibition of SGLT1 protects against glycemic variability-induced cardiac damage and pyroptosis of cardiomyocytes in diabetic mice.

Q. Chai, Weihua Wu, Zhenjie Sun, 2021, Life sciences.

LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration

Yu Hou, Qingqing Li, yang-xin fu, 2016, Nature Communications.

Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity

Guoliang Cui, J. Qiu, Jinxin Qiu, 2020, Mucosal Immunology.

Discovery of novel PTP1B inhibitors with antihyperglycemic activity

Jia Li, Jing-kang Shen, Q. Chai, 2010, Acta Pharmacologica Sinica.

Langerhans Cells Control Lymphatic Vessel Function during Inflammation via LIGHT-LTβR Signaling

Mingzhao Zhu, Q. Chai, Wenjun Wang, 2019, The Journal of Immunology.

IL-7-producing stromal cells are critical for lymph node remodeling.

Mark Coles, Burkhard Ludewig, Elke Scandella, 2012, Blood.

Establishment of a CCL19/CCL21 dual transgenic system for investigating the functions of T cell zone stromal cells

Qian Chai, 2013 .

Organization of Ribosomes and Nucleoids in Escherichia coli Cells during Growth and in Quiescence*

S. Sanyal, S. Dasgupta, Bhupender Singh, 2014, The Journal of Biological Chemistry.

Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity

Guoliang Cui, J. Qiu, Jinxin Qiu, 2020, Mucosal Immunology.

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

B. Ludewig, C. Ebens, Minhong Yan, 2017, The Journal of clinical investigation.

Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity

Thomas Rülicke, Jens V. Stein, Burkhard Ludewig, 2013, Immunity.

A Novel Bacterial Artificial Chromosome-Transgenic Podoplanin–Cre Mouse Targets Lymphoid Organ Stromal Cells in vivo

T. Rülicke, B. Ludewig, V. Thiel, 2011, Front. Immun..

Endothelial cell–specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation

B. Ludewig, L. Onder, E. Scandella, 2013, The Journal of experimental medicine.

Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs

Shinya Abe, K. McCoy, B. Ludewig, 2016, Nature Immunology.

Type 3 Innate Lymphoid Cells Direct Goblet Cell Differentiation via the LT–LTβR Pathway during Listeria Infection

Mengjie Lv, Mingzhao Zhu, J. Qiu, 2020, The Journal of Immunology.

IFN-γ–Producing CD4+ T Cells Promote Generation of Protective Germinal Center–Derived IgM+ B Cell Memory against Salmonella Typhi

A. Waisman, B. Ludewig, C. Perez-Shibayama, 2014, The Journal of Immunology.

Salmonella B Cell Memory against + Derived IgM - Generation of Protective Germinal Center T Cells Promote + Producing CD4 - γ IFN-

B. Ludewig, A. Isibasi, L. Onder, 2014 .

Differential Roles of LTβR in Endothelial Cell Subsets for Lymph Node Organogenesis and Maturation

Mingzhao Zhu, Q. Chai, Zhongnan Wang, 2018, The Journal of Immunology.

The ssrA-Tag Facilitated Degradation of an Integral Membrane Protein.

Yinan Wei, Zhaoshuai Wang, Stacy R. Webb, 2016, Biochemistry.

Kristin Peisker , and in Quiescence Cells During Growth Escherichia coli in Organization of Ribosomes and Nucleoids Cell Biology : published online March

S. Sanyal, S. Dasgupta, Bhupender Singh, 2014 .

and in Quiescence Cells during Growth Escherichia coli in Organization of Ribosomes and Nucleoids

S. Sanyal, Bhupender Singh, Kristin Peisker, 2014 .

Thymic Egress Is Regulated by T Cell-Derived LTβR Signal and via Distinct Thymic Portal Endothelial Cells

Xiaoqun Wang, Yixia Zhao, Mingzhao Zhu, 2021, Frontiers in Immunology.

Brief Definitive Report Endothelial Cell–specific Lymphotoxin- Receptor Signaling Is Critical for Lymph Node and High Endothelial Venule Formation the Development of Lymph Nodes (lns) and Formation of Ln Stromal Cell Microenvironments Is Dependent on Lymphotoxin- Receptor (ltr) Signaling. in Part

B. Ludewig, L. Onder, E. Scandella, 2022 .

Accessibility from the Cytoplasm Is Critical for ssrA Tag-Mediated Degradation of Integral Membrane Proteins by ClpXP Protease.

Yinan Wei, Zhaoshuai Wang, Q. Chai, 2018, Biochemistry.

Intermittent high glucose induces pyroptosis of rat H9C2 cardiomyocytes via sodium–glucose cotransporter 1

Q. Chai, Meili Liu, Weihua Wu, 2021, Molecular and Cellular Biochemistry.

Functional Relevance of AcrB Trimerization in Pump Assembly and Substrate Binding

Yinan Wei, Zhaoshuai Wang, W. Lu, 2014, PloS one.

Repressive mutations restore function-loss caused by the disruption of trimerization in Escherichia coli multidrug transporter AcrB

Yinan Wei, Zhaoshuai Wang, W. Lu, 2015, Front. Microbiol..

Correlation between AcrB Trimer Association Affinity and Efflux Activity

Yinan Wei, Zhaoshuai Wang, W. Lu, 2014, Biochemistry.

Inhibition of SGLT1 Alleviates the Glycemic Variability-Induced Cardiac Fibrosis via Inhibition of Activation of Macrophage and Cardiac Fibroblasts

Q. Chai, Weihua Wu, Ziying Zhang, 2021, Molecular and cellular biology.

Study of the degradation of a multidrug transporter using a non-radioactive pulse chase method

Yinan Wei, Zhaoshuai Wang, R. Dutch, 2016, Analytical and Bioanalytical Chemistry.

Insights into the Function and Structural Flexibility of the Periplasmic Molecular Chaperone SurA

Yinan Wei, W. Lu, Brent Ferrell, 2012, Journal of bacteriology.

Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1).

Weihua Wu, Ziying Zhang, Qian Chai, 2021, Archives of biochemistry and biophysics.

SGLT1 knockdown prevents glucose fluctuation-induced apoptosis of cardiomyocytes through attenuating oxidative stress and mitochondrial dysfunction.

Meili Liu, Weihua Wu, Jiajing Miao, 2020, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Diverse sequences are functional at the C-terminus of the E. coli periplasmic chaperone SurA.

Yinan Wei, Brent Ferrell, Xinyi Zhang, 2014, Protein engineering, design & selection : PEDS.

A Novel Bacterial Artificial Chromosome-Transgenic Podoplanin–Cre Mouse Targets Lymphoid Organ Stromal Cells in vivo

T. Rülicke, B. Ludewig, V. Thiel, 2011, Front. Immun..

Neutrophil-to-lymphocyte ratio is associated with coronary microvascular dysfunction in type 2 diabetes mellitus patients.

Meili Liu, Weihua Wu, Ziying Zhang, 2021, Diabetes research and clinical practice.

Role of a conserved residue R780 in Escherichia coli multidrug transporter AcrB.

Yinan Wei, Zhaoshuai Wang, W. Lu, 2013, Biochemistry.

Assembling of AcrB trimer in cell membrane.

Yinan Wei, Huilin Li, W. Lu, 2012, Journal of molecular biology.