S. Maher

发表

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Juan A. Bueren-Calabuig, Andrei V. Pisliakov, David W. Gray, 2019, Proceedings of the National Academy of Sciences.

Regulatory Hotspots in the Malaria Parasite Genome Dictate Transcriptional Variation

S. Wuchty, P. Rathod, Asako Tan, 2008, PLoS biology.

Enhancing longevity of Plasmodium vivax and P. falciparum sporozoites after dissection from mosquito salivary glands.

J. Sattabongkot, N. Singh, Steven P. Maher, 2015, Parasitology international.

An adaptable soft-mold embossing process for fabricating optically-accessible, microfeature-based culture systems and application toward liver stage antimalarial compound testing.

D. Kyle, C. Andolina, Brice Campo, 2020, Lab on a chip.

Atypical Mitogen-Activated Protein Kinase Phosphatase Implicated in Regulating Transition from Pre-S-Phase Asexual Intraerythrocytic Development of Plasmodium falciparum

J. Rayner, M. Zhang, T. Otto, 2013, Eukaryotic Cell.

asexual intraerythrocytic development of Plasmodium falciparum 2

J. Rayner, T. Otto, N. Singh, 2013 .

Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets

D. Kyle, I. Mueller, A. Jex, 2022, bioRxiv.

Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures

I. Mueller, A. Jex, G. Snounou, 2021, bioRxiv.

Characterization of the Tubovesicular Network in Plasmodium vivax Liver Stage Hypnozoites and Schizonts

D. Kyle, Kayla Sylvester, B. Witkowski, 2021, Frontiers in Cellular and Infection Microbiology.

The tubovesicular network in Plasmodium vivax liver-stage hypnozoites and schizonts associates with host aquaporin 3

D. Kyle, Kayla Sylvester, B. Witkowski, 2020, bioRxiv.

Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages

M. Galinski, D. Kyle, L. Rénia, 2019, Nature Communications.

A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages

S. Kappe, D. Kyle, D. Sather, 2018, Malaria Journal.

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

S. Kappe, D. Kyle, C. Andolina, 2018, Nature Communications.

Microphysical space of a liver sinusoid device enables simplified long-term maintenance of chimeric mouse-expanded human hepatocytes

D. Kyle, W. Saadi, J. Cuiffi, 2014, Biomedical microdevices.

Development of an efficient human hepatocyte culture platform for assessing novel therapeutic efficacy against Plasmodium liver parasites

Steven P. Maher, S. Maher, 2014 .

Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12)

D. Kyle, S. Charman, C. Kocken, 2022, ACS omega.

Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro

D. Kyle, C. Andolina, F. Nosten, 2021, Scientific Reports.

Bmc Microbiology

J. Kissinger, M. Fraser, J. Adams, 2009 .

Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1H)-Quinolones with Single Dose Cures.

D. Kyle, P. Parvatkar, Roman Manetsch, 2021, Journal of medicinal chemistry.

Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.

M. Cassera, E. F. Merino, D. Kyle, 2022, International journal for parasitology.

A rapid sensitive, flow cytometry-based method for the detection of Plasmodium vivax-infected blood cells

K. Williamson, J. Sattabongkot, W. Roobsoong, 2014, Malaria Journal.

Alkyne modified purines for assessing activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp

M. Cassera, E. F. Merino, D. Kyle, 2021, bioRxiv.

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

S. Lonardi, M. Galinski, K. L. Le Roch, 2023, bioRxiv.

Liver-stage fate determination in Plasmodium vivax parasites: Characterization of schizont growth and hypnozoite fating from patient isolates

D. Kyle, B. Witkowski, A. Vantaux, 2022, bioRxiv.

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3

D. Kyle, Kayla Sylvester, J. Popovici, 2020, Cell chemical biology.

A Phenotypic Screen for the Liver Stages of Plasmodium vivax.

D. Kyle, C. Joyner, B. Witkowski, 2021, Bio-protocol.

Cryopreservation of Plasmodium Sporozoites

D. Kyle, S. P. Kurup, L. Hancox, 2022, Pathogens.

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

Manuel Llinás, Yingyao Zhou, David A. Fidock, 2018, Science.

Cross-resistance of the chloroquine-derivative AQ-13 with amodiaquine in Cambodian Plasmodium falciparum isolates

D. Leroy, B. Witkowski, R. Leang, 2021, The Journal of antimicrobial chemotherapy.

CCR4-Associated Factor 1 Coordinates the Expression of Plasmodium falciparum Egress and Invasion Proteins

J. Rayner, R. Andrews, P. Ellis, 2011, Eukaryotic Cell.

A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages

S. Kappe, D. Kyle, D. Sather, 2018, Malaria Journal.

Synthesis of Mono- and Bisperoxide-Bridged Artemisinin Dimers to Elucidate the Contribution of Dimerization to Antimalarial Activity.

D. Kyle, Roman Manetsch, Victoria C Mendiola, 2021, ACS infectious diseases.

A Genetic Screen for Attenuated Growth Identifies Genes Crucial for Intraerythrocytic Development of Plasmodium falciparum

N. Singh, J. Adams, Bharath Balu, 2010, PloS one.

A highly sensitive, PCR-based method for the detection of Plasmodium falciparum clones in microtiter plates

Steven P. Maher, J. Adams, Bharath Balu, 2008, Malaria Journal.

piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome

J. Kissinger, M. Fraser, J. Adams, 2009, BMC Microbiology.

Single-cell RNA profiling of Plasmodium vivax liver stages reveals parasite- and host-

A. Jex, C. Joyner, B. Witkowski, 2022 .

Title: A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

S. Lonardi, M. Galinski, K. L. Le Roch, 2023 .