Xu-Nian Wu

Structure-based design, synthesis, and biological evaluation of novel pyrimidinone derivatives as PDE9 inhibitors

Yadan Huang, Hai-bin Luo, Chen Zhang, 2018, Acta pharmaceutica Sinica. B.

Free energy perturbation (FEP)-guided scaffold hopping

Hai-bin Luo, Zhe Li, Yi-You Huang, 2021, Acta pharmaceutica Sinica. B.

A novel inhibitor of N6-methyladenosine demethylase FTO induces mRNA methylation and shows anti-cancer activities

Jiawang Zhou, Hongsheng Wang, Shuibin Lin, 2021, Acta pharmaceutica Sinica. B.

The Overall Survival and Safety of Men with Metastatic Hormone-Sensitive Prostate Cancer Treated with Combination Therapy of Novel Androgen Receptor Antagonists and Androgen-Deprivation Therapy: A Systematic Review and Meta-Analysis

Chao Zhang, W. Song, Xu-Nian Wu, 2022, Journal of oncology.

Structure-based discovery of orally efficient inhibitors via unique interactions with H-pocket of PDE8 for the treatment of vascular dementia

Yadan Huang, Hai-bin Luo, Zhe Li, 2022, Acta pharmaceutica Sinica. B.

Rational Design of 2-Chloroadenine Derivatives as Highly Selective Phosphodiesterase 8A Inhibitors.

Yadan Huang, Hai-bin Luo, Zhe Li, 2020, Journal of medicinal chemistry.

Discovery of Novel Pyrazolopyrimidinone Derivatives as Phosphodiesterase 9A Inhibitors Capable of Inhibiting Butyrylcholinesterase for Treatment of Alzheimer's Disease.

Yadan Huang, Hai-bin Luo, Deyan Wu, 2017, ACS chemical neuroscience.

Discovery of novel PDE9A inhibitors with antioxidant activities for treatment of Alzheimer’s disease

Yadan Huang, Hai-bin Luo, Qian Zhou, 2017, Journal of enzyme inhibition and medicinal chemistry.

Transition-Metal-Free C–H Arylation of Unactivated Arenes with 8-Hydroxyquinoline as a Promoter

Hai-bin Luo, Deyan Wu, Xuehua Zheng, 2018, Synthesis.