Michino Murakami

The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor.

K. Fujishige, J. Kotera, K. Omori, 2014, Bioorganic & medicinal chemistry letters.

Design and synthesis of novel 5-(3,4,5-trimethoxybenzoyl)-4-aminopyrimidine derivatives as potent and selective phosphodiesterase 5 inhibitors: scaffold hopping using a pseudo-ring by intramolecular hydrogen bond formation.

K. Fujishige, J. Kotera, K. Omori, 2014, Bioorganic & medicinal chemistry letters.