Y. Hase

Conformational Restriction by Repulsion between Adjacent Substituents on a Cyclopropane Ring: Design and Enantioselective Synthesis of 1-Phenyl-2-(1-aminoalkyl)-N,N-diethylcyclopropanecarboxamides as Potent NMDA Receptor Antagonists

S. Shuto, A. Matsuda, S. Ono, 1996 .

Synthesis of (+)- and (−)-milnaciprans and their conformationally restricted analogs

S. Shuto, A. Matsuda, S. Ono, 1996 .

Synthesis and biological activity of conformationally restricted analogs of milnacipran: (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxami de, an efficient noncompetitive N-methyl-D-aspartic acid receptor antagonist.

S. Shuto, T. Noguchi, Y. Ueno, 1996, Journal of medicinal chemistry.

(+/-)-(Z)-2-(aminomethyl)-1-phenylcyclopropanecarboxamide derivatives as a new prototype of NMDA receptor antagonists.

S. Shuto, A. Matsuda, R. Tsujita, 1995, Journal of medicinal chemistry.