Pengxiang Huang*

发表

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ

S. Khorasanizadeh, F. Rastinejad, D. Mcclure, 2007, Nature Structural &Molecular Biology.

Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors.

Ruili Huang, C. Austin, Jun R Huh, 2013, ACS medicinal chemistry letters.

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

Dan R. Littman, Maria Ciofani, Fabio R. Santori, 2011, Nature.

Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics.

Vikas Chandra, F. Rastinejad, V. Chandra, 2010, Annual review of physiology.

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

Yoshitomo Hamuro, Vikas Chandra, Y. Hamuro, 2008, Nature.

Structural Basis of Smoothened Activation in Hedgehog Signaling

A. Salic, Youngchang Kim, Sanduo Zheng, 2018, Cell.

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.

S. Khorasanizadeh, F. Rastinejad, D. Mcclure, 2007, Nature structural & molecular biology.

Understanding nuclear receptor form and function using structural biology.

S. Khorasanizadeh, F. Rastinejad, V. Chandra, 2013, Journal of molecular endocrinology.

Identification of natural RORγ ligands that regulate the development of lymphoid cells.

S. A. van de Pavert, D. Littman, S. Horvat, 2015, Cell metabolism.

Corecognition of DNA and a methylated histone tail by MSL3 chromodomain

S. Khorasanizadeh, B. J. Blus, F. Rastinejad, 2010, Nature Structural &Molecular Biology.

Multi-Domain Integration in the Structure of the HNF4α Nuclear Receptor Complex

Dalei Wu, Youngchang Kim, F. Rastinejad, 2013, Nature.

Retinoic acid actions through mammalian nuclear receptors.

F. Rastinejad, V. Chandra, Pengxiang Huang*, 2014, Chemical reviews.

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling

A. Salic, Youngchang Kim, Cindy Y. Jao, 2016, Cell.

Beliefs and perceptions of electronic cigarettes among medical staff in respiratory departments of Fujian Province, China, in 2021

Xiaoping Lin, Weijing Wu, Fei He, 2022, Tobacco induced diseases.

Ceramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy

Linghong Guo, Gang Chen, Hang Sun, 2021, Cell Death & Disease.

Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex.

A. Salic, Jiansen Jiang, Sara García-Linares, 2022, Developmental cell.

Generation of sphingosine-1-phosphate by sphingosine kinase 1 protects nonalcoholic fatty liver from ischemia/reperfusion injury through alleviating reactive oxygen species production in hepatocytes.

Jie Peng, Hang Sun, Jie Zhou, 2020, Free radical biology & medicine.

Nonalcoholic steatohepatitis critically rewires the ischemia/reperfusion-induced dysregulation of cardiolipins and sphingolipids in mice

Hang Sun, Qifan Zhang, Jie Zhou, 2021, Hepatobiliary surgery and nutrition.

Structural Basis of Smoothened Activation in Hedgehog Signaling

A. Kruse, A. Salic, Youngchang Kim, 2018, Cell.

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

Y. Hamuro, F. Rastinejad, V. Chandra, 2008, Nature.

Retinoic acid actions through mammalian nuclear receptors.

F. Rastinejad, V. Chandra, Pengxiang Huang*, 2014, Chemical reviews.

Understanding nuclear receptor form and function using structural biology.

S. Khorasanizadeh, F. Rastinejad, V. Chandra, 2013, Journal of molecular endocrinology.

Identification of natural RORγ ligands that regulate the development of lymphoid cells.

S. A. van de Pavert, D. Littman, S. Horvat, 2015, Cell metabolism.