Xiao Ding

发表

Use of the Cassette-Dosing Approach to Assess Brain Penetration in Drug Discovery

Xingrong Liu, B. Liederer, C. Hop, 2012, Drug Metabolism and Disposition.

Use of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis Studies

Xingrong Liu, B. Liederer, X. Ding, 2015, Drug Metabolism and Disposition.

Simultaneous determination of itraconazole, hydroxy itraconazole, keto itraconazole and N-desalkyl itraconazole concentration in human plasma using liquid chromatography with tandem mass spectrometry.

J. Ware, Yuan Chen, J. Mao, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The Use of Betaine HCl to Enhance Dasatinib Absorption in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria

L. Benet, J. Ware, L. Salphati, 2014, The AAPS Journal.

Determination of unbound vismodegib (GDC-0449) concentration in human plasma using rapid equilibrium dialysis followed by solid phase extraction and high-performance liquid chromatography coupled to mass spectrometry.

Wenbin Liu, H. Wong, M. Meng, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Impact of food and the proton pump inhibitor rabeprazole on the pharmacokinetics of GDC-0941 in healthy volunteers: bench to bedside investigation of pH-dependent solubility.

J. Ware, R. Sutton, L. Salphati, 2013, Molecular pharmaceutics.

Ser1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations

K. Scearce-Levie, M. P. van der Brug, Xingrong Liu, 2012, Science Translational Medicine.

Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors

Marie Evangelista, F. Peale, Yuan Chen, 2016, Clinical Cancer Research.

Absorption, metabolism and excretion of pictilisib, a potent pan-class I phosphatidylinositol-3-Kinase (PI3K) inhibitor, in rats, dogs, and humans

J. Ware, L. Salphati, Shuguang Ma, 2021, Xenobiotica; the fate of foreign compounds in biological systems.

Equilibrative Nucleoside Transporter 3 Deficiency Perturbs Lysosome Function and Macrophage Homeostasis

D. Seshasayee, Cécile Chalouni, L. Rangell, 2012, Science.

Balancing Blood Sample Volume with 3Rs: Implementation and Best Practices for Small Molecule Toxicokinetic Assessments in Rats.

Brian Dean, Jacqueline Tarrant, B. Liederer, 2016, ILAR journal.

SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition

Kimberly Scearce-Levie, Dani Brunner, Qiang Zhou, 2013, PloS one.

Supercritical fluid chromatography‐tandem mass spectrometry for high throughput bioanalysis of small molecules in drug discovery

Jianshuang Wang, B. Dean, Xiaolin Zhang, 2019, Journal of pharmaceutical and biomedical analysis.

Prediction of drug distribution in subcutaneous xenografts of human tumor cell lines and healthy tissues in mouse: application of the tissue composition-based model to antineoplastic drugs.

B. Liederer, S. Gould, C. Hop, 2015, Journal of pharmaceutical sciences.

Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats

Xingrong Liu, J. Cheong, X. Ding, 2014, Drug Metabolism and Disposition.

Development of a multi‐matrix LC–MS/MS method for urea quantitation and its application in human respiratory disease studies

Fang Cai, X. Ding, Jianshuang Wang, 2017, Journal of pharmaceutical and biomedical analysis.

High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening.

Xingrong Liu, B. Liederer, C. Hop, 2013, Rapid communications in mass spectrometry : RCM.

Use of Subcutaneous and Intraperitoneal Administration Methods to Facilitate Cassette Dosing in Microdialysis Studies in Rats

Xingrong Liu, B. Liederer, M. Durk, 2018, Drug Metabolism and Disposition.

Abstract CT139: Phase I study of GDC-0425, a checkpoint kinase 1 inhibitor, in combination with gemcitabine in patients with refractory solid tumors

F. Peale, Yuan Chen, P. LoRusso, 2015 .

Determination of GDC-0980 (apitolisib), a small molecule dual phosphatidylinositide 3-kinase/mammalian target of rapamycin inhibitor in dog plasma by LC-MS/MS to support a GLP toxicology study.

L. Salphati, S. Reuschel, M. Meng, 2015, Biomedical chromatography : BMC.

A multi‐matrix HILIC‐MS/MS method for the quantitation of endogenous small molecule neurological biomarker N‐acetyl aspartic acid (NAA)

S. Shahidi-Latham, B. Dean, Dewakar Sangaraju, 2017, Journal of pharmaceutical and biomedical analysis.

The Use of Betaine HCl to Enhance Dasatinib Absorption in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria

L. Benet, J. Ware, L. Salphati, 2014, The AAPS Journal.

Preclinical stereoselective disposition and toxicokinetics of two novel MET inhibitors

D. Sutherlin, Xingrong Liu, B. Liederer, 2012, Xenobiotica; the fate of foreign compounds in biological systems.