Jiajun Yap

发表

Active and Passive Security Attacks in Wireless Networks and Prevention Techniques

Sun Jun Ee, Jeshua Woon Tien Ming, Jia Suan Yap, 2020 .

Drug resistance in targeted cancer therapies with RAF inhibitors

Jiancheng Hu, Ufuk Degirmenci, Shi-ni Qin, 2021, Cancer drug resistance.

Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis

Zhongzhou Chen, Jiancheng Hu, M. Baccarini, 2018, Science Signaling.

The Activation of MEK1 by Enhanced Homodimerization Drives Tumorigenesis

Jiancheng Hu, M. Baccarini, Zizi Tian, 2017, bioRxiv.

The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy

Jiancheng Hu, Xiaoduo Dong, Jimin Yuan, 2020, Journal of Hematology & Oncology.

The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants

Jiancheng Hu, Mei Wang, M. Baccarini, 2018, bioRxiv.

The stability of R-spine defines RAF inhibitor resistance: A comprehensive analysis of oncogenic BRAF mutants with in-frame insertion of αC-β4 loop

Zhongzhou Chen, Jiancheng Hu, Ufuk Degirmenci, 2021, Science Advances.

The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho–Ser-621 in the C terminus of CRAF

Jiancheng Hu, Mei Wang, Jimin Yuan, 2018, The Journal of Biological Chemistry.

AMPKi overcomes the paradoxical activation of CRAF driven by RAF inhibitors through blocking the 14-3-3 binding to its carboxyl-terminus

Jiancheng Hu, Mei Wang, Jimin Yuan, 2018, bioRxiv.

BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes

K. Sabapathy, Jiancheng Hu, Z. Lao, 2023, Molecular Cancer.