J. Karlo

发表

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Donald A. Wilson, D. Wesson, G. Landreth, 2012, Science.

Nerve Growth Factor Stimulates the Concentration of TrkA within Lipid Rafts and Extracellular Signal-Regulated Kinase Activation through c-Cbl-Associated Protein

G. Landreth, J. Karlo, A. Limpert, 2007, Molecular and Cellular Biology.

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

R. Ransohoff, S. Staugaitis, G. Landreth, 2015, The Journal of experimental medicine.

The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing of Oligodendrocyte Differentiation

G. Landreth, Robert H Miller, J. C. Karlo, 2011, The Journal of Neuroscience.

Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor-γ-Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease

G. Landreth, Shweta Mandrekar-Colucci, J. Karlo, 2012, The Journal of Neuroscience.

Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice

G. Landreth, A. Gozzi, R. Brambilla, 2018, The Journal of Neuroscience.

The 16p11.2 Deletion Mouse Model of Autism Exhibits Altered Cortical Progenitor Proliferation and Brain Cytoarchitecture Linked to the ERK MAPK Pathway

Joseph Vithayathil, G. Landreth, Gary E. Landreth, 2015, The Journal of Neuroscience.

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

D. Ginty, S. Saitta, G. Landreth, 2008, Proceedings of the National Academy of Sciences.

Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.

G. Landreth, D. Johnson, S. Cannady, 2000, The Journal of neuroscience : the official journal of the Society for Neuroscience.

β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis

G. Landreth, S. Kao, C. Combs, 2001, The Journal of Neuroscience.

beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

G. Landreth, S. Kao, C. Combs, 2001, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Erk1 and Erk2 Regulate Endothelial Cell Proliferation and Migration during Mouse Embryonic Angiogenesis

Michael C. Ostrowski, Tahera Zabuawala, G. Landreth, 2009, PloS one.

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease

R. Ransohoff, G. Landreth, B. Lamb, 2018, Molecular Neurodegeneration.

inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models

R. Ransohoff, S. Staugaitis, G. Landreth, 2015 .

Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease

G. Landreth, B. Casali, M. Mariani, 2015, The Journal of Neuroscience.

Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARγ Agonists

G. Landreth, S. Cannady, C. Combs, 2000, The Journal of Neuroscience.

Regulation of β-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor α

G. Landreth, C. Combs, P. Bates, 2001, Neurochemistry International.

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease

R. Ransohoff, G. Landreth, B. Lamb, 2018, Molecular Neurodegeneration.

Deletion of ERK2 Mitogen-Activated Protein Kinase Identifies Its Key Roles in Cortical Neurogenesis and Cognitive Function

J. Sweatt, K. Herrup, S. Saitta, 2008, The Journal of Neuroscience.

Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor alpha.

G. Landreth, J. C. Karlo, C. Combs, 2001, Neurochemistry international.

Disrupted ERK Signaling during Cortical Development Leads to Abnormal Progenitor Proliferation, Neuronal and Network Excitability and Behavior, Modeling Human Neuro-Cardio-Facial-Cutaneous and Related Syndromes

Pavel A. Puzerey, G. Landreth, J. Pucilowska, 2012, The Journal of Neuroscience.

A novel cDNA from Drosophila encoding a protein with similarity to mammalian cysteine-rich secretory proteins, wasp venom antigen 5, and plant group 1 pathogenesis-related proteins.

G. Kovalick, M. Schreiber, J. Karlo, 1997, Gene.

The PPARγ agonist pioglitazone crosses the blood–brain barrier and reduces tumor growth in a human xenograft model

C. Grommes, G. Landreth, A. Caprariello, 2013, Cancer Chemotherapy and Pharmacology.

Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral 3 Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice

J. Karlo, G. Landreth, C. Robol, 2022 .