H. Onaran

发表

Ca2+-Induced Inhibition of Adenylyl Cyclase in Turkey Erythrocyte Membranes

Ö. Uğur, E. Demirel, H. Onaran, 1998, Pharmacology.

A Look at Receptor Efficacy. From the Signalling Network of the Cell to the Intramolecular Motion of the Receptor

A. Scheer, Alexander Scheer, T. Costa, 2000 .

Vasopressin receptor 2 mutations in the nephrogenic syndrome of inappropriate antidiuresis show different mechanisms of constitutive activation for G protein coupled receptors

P. Molinari, T. Costa, C. Ambrosio, 2020, Scientific Reports.

Supplementary information to : Systematic errors in detecting biased agonism . Analysis of current methods and development of a new model-free approach

Tommaso Costa, H. Ongun Onaran, Caterina Ambrosio, 2017 .

Coupling of β2-Adrenoceptors to XLαs and Gαs: A New Insight into Ligand-Induced G Protein Activation

M. Bastepe, A. Kaya, H. O. Onaran, 2009, Journal of Pharmacology and Experimental Therapeutics.

Coupling of 2-Adrenoceptors to XL

Ö. Uğur, M. Bastepe, A. Kaya, 2009 .

Kinetics of antagonism at histamine-H1 receptors in isolated rabbit arteries

H. O. Onaran, T. A. Bökesoy, H. Onaran, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Atypical Schild plots with histamine H1 receptor agonists and antagonists in the rabbit aorta.

T. A. Bökesoy, H. Onaran, 1991, European journal of pharmacology.

Role of alpha-adrenoceptors in the effects of buspirone and 5-carboxamidotryptamine in rabbit isolated thoracic aorta.

H. O. Onaran, H. Gürdal, F. Tulunay, 1992, General pharmacology.

Cell Contact-dependent Functional Selectivity of β2-Adrenergic Receptor Ligands in Stimulating cAMP Accumulation and Extracellular Signal-regulated Kinase Phosphorylation*

Ö. Uğur, A. Kaya, T. Costa, 2012, The Journal of Biological Chemistry.

Community guidelines for GPCR ligand bias: IUPHAR review 32

David E. Gloriam, Stephen P. H. Alexander, R. Neubig, 2022, British journal of pharmacology.

Pharmacokinetics of recombinant human erythropoietin in children with chronic renal failure

N. Akar, M. Eki̇m, N. Çakar, 2006, International Urology and Nephrology.

Ligands Raise the Constraint That Limits Constitutive Activation in G Protein-coupled Opioid Receptors*

G. Balboni, P. Molinari, G. Calo’, 2013, The Journal of Biological Chemistry.

Guanine Nucleotide Exchange-Independent Activation of Gs Protein by β2-Adrenoceptor

P. Molinari, K. Sayar, H. O. Onaran, 2005, Molecular Pharmacology.

Lysolipids reversibly inhibit Ca2+‐, GTP‐ and pH‐dependent fusion of biological membranes

Steven S. Vogel, J. Zimmerberg, L. Chernomordik, 1993, FEBS letters.

Quasi-irreversible binding of agonist to beta-adrenoceptors and formation of non-dissociating receptor-G(s) complex in the absence of guanine nucleotides.

H. O. Onaran, H. Gurdal, H. Onaran, 2001, European journal of pharmacology.

Beta gamma subunits of guanine nucleotide-binding proteins and regulation of spontaneous receptor activity: thermodynamic model for the interaction between receptors and guanine nucleotide-binding protein subunits.

D. Rodbard, T. Costa, H. O. Onaran, 1993, Molecular pharmacology.

Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand.

D Rodbard, D. Rodbard, T Costa, 1992, Molecular pharmacology.

Allosteric equilibrium model explains steady-state coupling of beta-adrenergic receptors to adenylate cyclase in turkey erythrocyte membranes.

O. Uğur, H. Onaran, 1997, The Biochemical journal.

An efficacy-dependent effect of cardiac overexpression of beta2-adrenoceptor on ligand affinity in transgenic mice.

R. Bond, H. O. Onaran, M. Johnson, 1997, Molecular pharmacology.

What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling.

S. Rajagopal, T. Costa, H. O. Onaran, 2014, Trends in pharmacological sciences.

beta2-Adrenoceptor, Gs and adenylate cyclase coupling in purified detergent-resistant, low density membrane fractions.

A. Kaya, O. Uğur, S. Oner, 2010, European journal of pharmacology.

Conceptual and experimental issues in biased agonism.

T. Costa, H. O. Onaran, H. Onaran, 2021, Cellular signalling.

Long and short distance movements of β(2)-adrenoceptor in cell membrane assessed by photoconvertible fluorescent protein dendra2-β(2)-adrenoceptor fusion.

K. Sayar, A. Kaya, O. Uğur, 2011, Biochimica et biophysica acta.

Agonist‐directed trafficking explaining the difference between response pattern of naratriptan and sumatriptan in rabbit common carotid artery

H. O. Onaran, H. Gurdal, Demet Akin, 2002, British journal of pharmacology.

Agonist Efficacy and Aliosteric Models of Receptor Action a

T. Costa, H. Onaran, 1997, Annals of the New York Academy of Sciences.

Allosteric coupling and conformational fluctuations in proteins.

T. Costa, H. O. Onaran, H. Onaran, 2009, Current protein & peptide science.

Ligand efficacy and affinity in an interacting 7TM receptor model

H. O. Onaran, H. Gurdal, H. Onaran, 1999 .

Where have all the active receptor states gone?

T. Costa, H. Onaran, 2012, Nature chemical biology.

Biased agonism at G protein-coupled receptors.

Karim Nagi, H. Onaran, 2021, Cellular signalling.