Amin Rostami-Hodjegan

Biopharmaceutics data management system for anonymised data sharing and curation: First application with orbito IMI project

Philip Hayward, Xavier Pepin, Kristin Lacy-Jones, 2017, Comput. Methods Programs Biomed..

Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

Thu Thuy Nguyen, Amin Rostami-Hodjegan, Elke H J Krekels, 2018, Pharmaceutical Research.

A user-friendly physiologically-based pharmacokinetic (PBPK) brain model and its application in simulating drug disposition in brain

Amin Rostami-Hodjegan, Amin Rostami-Hochaghan, M Jamei, 2011 .

Development of a permeability-limited model of the human brain and cerebrospinal fluid (CSF) to integrate known physiological and biological knowledge: Estimating time varying CSF drug concentrations and their variability using in vitro data.

Lu Gaohua, Amin Rostami-Hodjegan, Masoud Jamei, 2016, Drug metabolism and pharmacokinetics.

Biosimulation in Biomedical Research, Health Care and Drug Development

Erik Mosekilde, Amin Rostami-Hodjegan, Olga Sosnovtseva, 2012, Springer Vienna.

A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4.

Lu Gaohua, Amin Rostami-Hodjegan, Masoud Jamei, 2012, British journal of clinical pharmacology.

Prediction of the Clearance of Eleven Drugs and Associated Variability in Neonates, Infants and Children

Amin Rostami-Hodjegan, Geoffrey T. Tucker, G. Tucker, 2006, Clinical pharmacokinetics.

A Physiologically Based Pharmacokinetic Model to Predict Disposition of CYP2D6 and CYP1A2 Metabolized Drugs in Pregnant Women

Ping Zhao, Nina Isoherranen, Amin Rostami-Hodjegan, 2013, Drug Metabolism and Disposition.

Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice

Amin Rostami-Hodjegan, A. Rostami-Hodjegan, T. Johnson, 2011, Paediatric anaesthesia.

Changes in liver volume from birth to adulthood: A meta‐analysis

Amin Rostami-Hodjegan, Geoffrey T Tucker, Trevor N Johnson, 2005, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Physiologically based pharmacokinetic (PBPK) modeling: it is here to stay!

Amin Rostami-Hodjegan, A. Rostami-Hodjegan, I. Tamai, 2012, Biopharmaceutics & drug disposition.

Anatomical, Physiological and Metabolic Changes with Gestational Age during Normal Pregnancy

Amin Rostami-Hodjegan, Khaled Abduljalil, P. Furness, 2012, Clinical Pharmacokinetics.

Application of in vitro-in vivo extrapolation (IVIVE) and physiologically based pharmacokinetic (PBPK) modelling to investigate the impact of the CYP2C8 polymorphism on rosiglitazone exposure

Amin Rostami-Hodjegan, A. Rostami-Hodjegan, K. Yeo, 2013, European Journal of Clinical Pharmacology.

Assessing the efficiency of mixed effects modelling in quantifying metabolism based drug–drug interactions: using in vitro data as an aid to assess study power

Amin Rostami-Hodjegan, Geoffrey T Tucker, Trevor N Johnson, 2009, Pharmaceutical statistics.

Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19.

Ping Zhao, Amin Rostami-Hodjegan, Jashvant D Unadkat, 2014, British journal of clinical pharmacology.

Fetal Physiologically-Based Pharmacokinetic Models: Systems Information on Fetal Biometry and Gross Composition

Amin Rostami-Hodjegan, Khaled Abduljalil, A. Rostami-Hodjegan, 2018, Clinical Pharmacokinetics.