Jia Li

发表

Isoprenylated Flavonoids with PTP1B Inhibition from Macaranga denticulata

A. Hou, Li-xin Gao, Chun Lei, 2016, Natural Products and Bioprospecting.

Flavans and diphenylpropanes with PTP1B inhibition from Broussonetia kazinoki.

Jia Li, Jingya Li, A. Hou, 2018, Fitoterapia.

Isoprenylated phenolic compounds with PTP1B inhibition from Morus alba.

Jia Li, Jingya Li, A. Hou, 2017, Fitoterapia.

Isoprenylated Flavonoids with PTP1B Inhibition from Macaranga denticulata

Jia Li, Jingya Li, A. Hou, 2016, Natural Products and Bioprospecting.

Isoprenylated Flavonoids with PTP1B Inhibition from Ficus tikoua

Jia Li, Jingya Li, A. Hou, 2015, Natural product communications.

Himalensines A and B, Alkaloids from Daphniphyllum himalense.

J. Yue, Hua Zhang, S. Shyaula, 2016, Organic letters.

Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies

Yongzhou Hu, Tao Liu, Lei Xu, 2021, Acta Pharmacologica Sinica.

Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators.

F. Nan, Jia Li, Jingya Li, 2013, ACS medicinal chemistry letters.

Design and synthesis of new potent PTP1B inhibitors with the skeleton of 2-substituted imino-3-substituted-5-heteroarylidene-1,3-thiazolidine-4-one: Part I.

Jia Li, Jingya Li, G. Meng, 2016, European journal of medicinal chemistry.

AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue

Haowen Jiang, Li-na Zhang, Bo-Han Li, 2018, Front. Physiol..

Bioactive Cembranoids from the Coral Sarcophyton trocheliophorum of Ximao Island

J. Chen, Hong Wang, Baofu Xu, 2022, ACS omega.

Metabolic Regulation of Gene Expression by Histone Lysine β‐hydroxybutyrylation

Hongyu Zhao, Chao Peng, Dongjun Chung, 2016, Molecular cell.

Benzo[c][1,2,5]thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.

Jingyu Zhu, Lei Xu, Li-xin Gao, 2017, Bioorganic & medicinal chemistry letters.

Discovery, synthesis, and structure-activity relationships of 20S-dammar-24-en-2α,3β,12β,20-tetrol (GP) derivatives as a new class of AMPKα2β1γ1 activators.

Lihong Hu, Jun-hua Liu, Chen-Ming Dong, 2016, Bioorganic & medicinal chemistry.

Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes.

Hualiang Jiang, Honglin Li, Xiaofeng Liu, 2016, Journal of medicinal chemistry.

(R)-3-amino-1-((3aS,7aS)-octahydro-1H-indol-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one derivatives as potent inhibitors of dipeptidyl peptidase-4: design, synthesis, biological evaluation, and molecular modeling.

Zeng Li, Hong Liu, Jiang Wang, 2014, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of 4-fluoropyrrolidine-2-carbonitrile and octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors.

Hualiang Jiang, X. Wan, Zeng Li, 2014, European journal of medicinal chemistry.

Design and Synthesis of 4‐(2,4,5‐Trifluorophenyl)butane‐1,3‐diamines as Dipeptidyl Peptidase IV Inhibitors

B. Xiong, Jing-kang Shen, Xin Wang, 2013, ChemMedChem.

Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity

Cheng Luo, Kai-Xian Chen, C. Luo, 2018, Marine drugs.

Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity.

Jia Li, Jingya Li, Li Zhang, 2016, Bioorganic & medicinal chemistry letters.

Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury

Jia Li, Jingya Li, A. Hou, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural Elucidation and Bioinspired Total Syntheses of Ascorbylated Diterpenoid Hongkonoids A-D.

J. Yue, Shan Wang, Li Sheng, 2018, Journal of the American Chemical Society.

SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue

Li-na Zhang, Bo-Han Li, Chun-lan Tang, 2019, Diabetes.

Design, synthesis and biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3',2':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5'-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes.

Haifeng Sun, Shengbin Zhou, Hong Liu, 2017, European journal of medicinal chemistry.

Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation

Wenying Huang, Jianping Ye, Xiaoying Zhang, 2023, Frontiers of medicine.

Activating Adenosine Monophosphate–Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice

M. Zheng, M. Mohammadi, M. Kong, 2020, Hepatology.

Hainanerectamines A–C, Alkaloids from the Hainan Sponge Hyrtios erecta

Yue‐Wei Guo, D. Xue, Li-gong Yao, 2014, Marine drugs.

Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans

Haowen Jiang, Hongcheng Shi, Mingfeng Xia, 2019, Cell Death & Disease.

Uncommon eunicellin-based diterpenoid and 9,11-secosteroid from the Sanya soft coral Cladiella krempfi: structure and stereochemistry

Hong Wang, Cheng-Shi Jiang, Yue‐Wei Guo, 2022, Tetrahedron Letters.

Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice

Haowen Jiang, Cheng-gang Huang, Shichao Cui, 2020, Acta Pharmacologica Sinica.

Six new diterpenoids from Croton laevigatus

J. Yue, Yao-yue Fan, Meng-meng Zhang, 2018, Journal of Asian natural products research.

DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation

Haowen Jiang, Bo-Han Li, Lin Shuai, 2021, Diabetes.

Enantiomeric Pairs of Meroterpenoids with Diverse Heterocyclic Systems from Rhododendron nyingchiense.

Jia Li, A. Hou, Pei-Pei Wang, 2018, Journal of natural products.

Enantiomeric pairs of meroterpenoids from Rhododendron fastigiatum.

A. Hou, Chun Lei, Ke-xin Zhu, 2019, Chinese journal of natural medicines.

Two Enantiomeric Pairs of Meroterpenoids from Rhododendron capitatum.

Jia Li, Jingya Li, A. Hou, 2015, Organic letters.

BMS309403 Stimulates Glucose Uptake in Myotubes through Activation of AMP-Activated Protein Kinase

Donghai Wu, Shouguang Jin, Jingya Li, 2012, PloS one.

Discovering Novel α‐aminoacyl‐Containing Proline Derivatives with Potent and Selective Inhibitory Activity Against Dipeptidyl Peptidase IV: Design, Synthesis, Biological Evaluation, and Molecular Modeling

Hong Liu, Xiaodong Zhang, Zeng Li, 2012, Chemical biology & drug design.

Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors.

Li-xin Gao, Cheng-Shi Jiang, Jing-xu Gong, 2015, Bioorganic & Medicinal Chemistry Letters.

Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3',2':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2',3':4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5'-monophosphate-activated protein kinase (AMPK

Kaixian Chen, Shengbin Zhou, Hong Liu, 2018, Bioorganic & medicinal chemistry.

Concise synthesis and PTP1B inhibitory activity of (R)- and (S)-dihydroresorcylide

Li Zhang, Cheng-Shi Jiang, Jing-xu Gong, 2017, Journal of Asian natural products research.

Discovery, synthesis, and structure-activity relationships of 20(S)-protopanaxadiol (PPD) derivatives as a novel class of AMPKα2β1γ1 activators.

Lihong Hu, P. Liu, Jia Li, 2014, European journal of medicinal chemistry.

Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans

Haowen Jiang, Hongcheng Shi, Mingfeng Xia, 2019, Cell Death & Disease.

Beneficial effects exerted by hydroxychloroquine in treating COVID-19 patients via protecting multiple organs

Hualiang Jiang, D. Wang, Bo Yu, 2020, Science China Life Sciences.

Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles.

Shimeng Guo, Yushe Yang, Xin Xie, 2018, Bioorganic & medicinal chemistry.

Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors.

Li-xin Gao, Cheng-Shi Jiang, Jing-xu Gong, 2015, Bioorganic & medicinal chemistry letters.

Metabolic Regulation of Gene Expression by Histone Lysine β‐hydroxybutyrylation

K. White, Dongjun Chung, R. Roeder, 2017, The FASEB Journal.

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation.

Hongyu Zhao, K. White, Dongjun Chung, 2016, Molecular cell.