Haifeng Zhao

发表

Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis.

O. El-Kabbani, A. Hara, T. Matsunaga, 2009, Biochemical and biophysical research communications.

Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroids.

O. El-Kabbani, Y. Kitade, A. Hara, 2009, Archives of biochemistry and biophysics.

Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10.

O. El-Kabbani, A. Hara, T. Matsunaga, 2012, European journal of medicinal chemistry.

Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase.

O. El-Kabbani, V. Carbone, A. Hara, 2009, Bioorganic & medicinal chemistry.

Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

Hong Liang, Zhen-Feng Chen, Zhenfeng Chen, 2012, Bioorganic & medicinal chemistry letters.

Novel hybrids of oxoisoaporphine-tryptamine as acetylcholinesterase-induced β-amyloid aggregation inhibitors with improved antioxidant properties

Huang Tang, Shu-Ming Zhong, Jiangke Qin, 2015 .

Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.

Satoshi Endo, O. El-Kabbani, M. Iinuma, 2011, Journal of natural products.

Inhibition of human aldose reductase-like protein (AKR1B10) by α- and γ-mangostins, major components of pericarps of mangosteen.

O. El-Kabbani, M. Iinuma, A. Hara, 2012, Biological & pharmaceutical bulletin.

Selectivity determinants of inhibitor binding to the tumour marker human aldose reductase-like protein (AKR1B10) discovered from molecular docking and database screening.

O. El-Kabbani, A. Hara, S. Endo, 2010, European journal of medicinal chemistry.

Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10.

Kazuo Kuwata, Yukio Kitade, Satoshi Endo, 2010, Bioorganic & medicinal chemistry.

Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.

O. El-Kabbani, M. Iinuma, T. Matsunaga, 2011, Journal of natural products.

Structure/function analysis of a critical disulfide bond in the active site of l-xylulose reductase

O. El-Kabbani, P. Hogg, A. Hara, 2009, Cellular and Molecular Life Sciences.