Michael Ewing

发表

An Autophagy-Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis

Simon Watkins, Amitava Mukherjee, Simon C Watkins, 2010, Science.

Regulator of G Signaling 16 Is a Marker for the Distinct Endoplasmic Reticulum Stress State Associated with Aggregated Mutant α1-Antitrypsin Z in the Classical Form of α1-Antitrypsin Deficiency*

K. Mirnics, D. Perlmutter, T. Hidvegi, 2007, Journal of Biological Chemistry.

NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms

D. Stolz, A. Mukherjee, D. Perlmutter, 2018, Cell Death & Differentiation.

The role of autophagy in alpha-1-antitrypsin deficiency.

A. Mukherjee, D. Perlmutter, Carolyn Kemp, 2011, Methods in enzymology.

Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy*

A. M. Houghton, J. Alcorn, N. Brunetti‐Pierri, 2015, The Journal of Biological Chemistry.

NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms

D. Stolz, A. Mukherjee, D. Perlmutter, 2019, Cell Death & Differentiation.

Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency

Joshua A. Benson, C. Dippold, G. Silverman, 2014, PloS one.

Loss of CREBRF reduces anxiety-like behaviors and circulating glucocorticoids in male and female mice.

K. Frahm, D. DeFranco, C. O'Donnell, 2020, Endocrinology.

A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress

D. Weeks, S. Rosenthal, B. Kaufman, 2021, bioRxiv.