Vladimir A. Pavlyukovets

发表

Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies

Dong Wook Kang, Sun Choi, Jin Hee Lee, 2011, J. Comput. Aided Mol. Des..

Insights into TRPV1 pharmacology provided by non-capsaicin ligands

Vladimir A. Pavlyukovets, P. Blumberg, L. Pearce, 2005 .

Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.

Vladimir A. Pavlyukovets, Sun Choi, Jeewoo Lee, 2009, Bioorganic & medicinal chemistry.

Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.

Vladimir A. Pavlyukovets, S. Y. Kim, Jeewoo Lee, 2005, Bioorganic & medicinal chemistry letters.

Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.

Vladimir A. Pavlyukovets, Jiyoun Lee, S. Y. Kim, 2005, Bioorganic & medicinal chemistry letters.

2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure-activity relationships in the B and C-regions.

Vladimir A. Pavlyukovets, P. Blumberg, Keliang Liu, 2012, Bioorganic & medicinal chemistry.

Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups.

Vladimir A. Pavlyukovets, P. Blumberg, S. Wincovitch, 2007, Journal of medicinal chemistry.

Halogenation of 4-hydroxy/amino-3-methoxyphenyl acetamide TRPV1 agonists showed enhanced antagonism to capsaicin.

Vladimir A. Pavlyukovets, P. Blumberg, L. Pearce, 2010, Bioorganic & medicinal chemistry.

Halogenation of 4-hydroxy-3-methoxybenzyl thiourea TRPV1 agonists showed enhanced antagonism to capsaicin.

Vladimir A. Pavlyukovets, Jeewoo Lee, P. Blumberg, 2007, Bioorganic & medicinal chemistry letters.

Alpha-substituted N-(4-tert-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists.

Vladimir A. Pavlyukovets, Sun Choi, S. Y. Kim, 2007, Bioorganic & medicinal chemistry.

Kinetics of Penetration Influence the Apparent Potency of Vanilloids on TRPV1

Vladimir A. Pavlyukovets, P. Blumberg, S. Wincovitch, 2006, Molecular Pharmacology.

The SAR analysis of TRPV1 agonists with the α-methylated B-region.

Vladimir A. Pavlyukovets, P. Blumberg, L. Pearce, 2012, Bioorganic & medicinal chemistry letters.