Léon Kautz

发表

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

M. Roth, H. Coppin, Delphine Meynard, 2009, Nature Genetics.

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia

T. Ganz, M. Roth, H. Coppin, 2017, Haematologica.

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.

T. Ganz, E. Nemeth, M. Nasoff, 2015, Blood.

IDENTIFICATION OF ERYTHROFERRONE AS AN ERYTHROID REGULATOR OF IRON METABOLISM

S. Rivella, E. Valore, T. Ganz, 2014, Nature Genetics.

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis.

T. Ganz, E. Nemeth, P. Ruchala, 2012, Blood.

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

T. Ganz, E. Nemeth, Y. Ginzburg, 2011, Hepatology.

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the Anemia of Chronic Disease.

A. Bosserhoff, S. Arndt, J. Carvalho, 2020, Blood.

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

R. Margueron, A. Stamatoullas, M. Stern, 2019, Science Translational Medicine.

Author Correction: Identification of erythroferrone as an erythroid regulator of iron metabolism

S. Rivella, E. Valore, T. Ganz, 2020, Nature Genetics.

Immunoassay for human serum erythroferrone.

T. Ganz, E. Nemeth, Y. Ginzburg, 2017, Blood.

Smad7, Id1, and Atoh8 in the mouse liver Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6,

J. Mosser, A. Monnier, S. Vaulont, 2013 .

Neurobiology Bmp 6 Regulates Retinal Iron Homeostasis and Has Altered Expression in Age-Related Macular Degeneration

M. Roth, J. Dunaief, Ying Song, 2011 .

Iron overload induces BMP6 expression in the liver but not in the duodenum

M. Roth, H. Coppin, Delphine Meynard, 2011, Haematologica.

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.

C. López-Otín, S. Vaulont, A. Ramsay, 2011, Blood.

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp 6 *

C. López-Otín, S. Vaulont, A. Ramsay, 2011 .

Novel tools for the evaluation of iron metabolism

E. Nemeth, L. Kautz, Léon Kautz, 2010, Haematologica.

Iron deficiency anemia due to matriptase-2 inactivation is dependent upon the presence of functional Bmp 6 Short title : Matriptase-2 and Bmp 6 deficiency in mice

C. López-Otín, S. Vaulont, A. Ramsay, 2010 .

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

M. Roth, H. Coppin, Delphine Meynard, 2009, Blood.

BMP / Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp 6 e xpression Running title : Bmp / Smad signaling defect in hemochromatotic mice

M. Roth, H. Coppin, Delphine Meynard, 2009 .

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.

Jean Mosser, J. Mosser, A. Monnier, 2008, Blood.

Transient decrease of serum iron after acute erythropoietin treatment contributes to hepcidin inhibition by ERFE in mice

M. Lidonnici, G. Ferrari, L. Silvestri, 2018, Haematologica.

Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone

D. Swinkels, N. Grebenchtchikov, R. Roelofs, 2021, PloS one.

Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin

T. Ganz, O. Loréal, M. Roth, 2014, Hepatology.

Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers

J. Mosser, Maria Martinez, M. Aubry, 2007, Genome Biology.

Erythroferrone contributes to recovery from anemia of inflammation.

T. Ganz, E. Nemeth, G. Jung, 2014, Blood.

Erythroferrone and matriptase‐2 independently regulate hepcidin expression

T. Ganz, E. Nemeth, V. Gabayan, 2017, American journal of hematology.

Molecular liaisons between erythropoiesis and iron metabolism.

E. Nemeth, L. Kautz, Léon Kautz, 2014, Blood.

RED CELLS , IRON , AND ERYTHROPOIESIS Erythroferrone contributes to recovery from anemia of in fl ammation

T. Ganz, E. Nemeth, G. Jung, 2014 .

Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.

T. Ganz, J. Bertrand, M. Roth, 2012, Blood.

Identification of serotonin as a gut regulator of liver hepcidin expression

J. Launay, C. Peyssonnaux, M. Foretz, 2023, bioRxiv.

Recoveryfrombloodlossrequiresagreatlyenhancedsupplyofirontosupportexpandederythropoiesis.Afterhemorrhage, suppressionoftheiron-regulatoryhormonehepcidinallowsincreasedironabsorptionandmobilizationfromstores.Weidentified anewhormone,erythroferrone(ERFE),thatmediateshepcidinsuppressionduringstresseryt

S. Rivella, E. Valore, T. Ganz, 2014 .

Testing the iron hypothesis in a mouse model of atherosclerosis.

A. Lusis, T. Ganz, B. Qiao, 2013, Cell reports.

The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice

T. Ganz, C. Peyssonnaux, E. Nemeth, 2023, bioRxiv.

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice

T. Ganz, E. Nemeth, L. Kautz, 2018, Physiological reports.

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

M. Roth, H. Coppin, Delphine Meynard, 2009, Nature Genetics.

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

T. Ganz, E. Nemeth, Y. Ginzburg, 2011, Hepatology.

Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin

T. Ganz, O. Loréal, M. Roth, 2014, Hepatology.

Molecular liaisons between erythropoiesis and iron metabolism.

E. Nemeth, Léon Kautz, 2014, Blood.

[Erythroferrone, an erythroid regulator of iron metabolism].

Léon Kautz, 2014, Medecine sciences : M/S.

RED CELLS, IRON, AND ERYTHROPOIESIS Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of b -thalassemia

T. Ganz, E. Nemeth, V. Gabayan, 2015 .

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.

J. Mosser, A. Monnier, S. Vaulont, 2008, Blood.