Mario Niepel

发表

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures

Andrew D. Rouillard, Avi Ma'ayan, Marc Hafner, 2014, Nucleic Acids Res..

Supplementary material from "Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer"

Heather A. Harrington, Birgit Schoeberl, Mariano Beguerisse-Díaz, 2019 .

Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE)

David Haussler, Peter K. Sorger, Evan O. Paull, 2013, Bioinform..

Abstract 5037: New concepts for quantifying the benefits of mono and combination therapy in an era of big data

Marc Hafner, Peter K. Sorger, Mario Niepel, 2017 .

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Ravi Iyengar, Vasileios Stathias, Amar Koleti, 2017, Cell systems.

L1000CDS2: LINCS L1000 characteristic direction signatures search engine

Marc Hafner, Rachel Hodos, Ben Readhead, 2016, npj Systems Biology and Applications.

Designing Drug‐Response Experiments and Quantifying their Results

Marc Hafner, Kartik Subramanian, Mario Niepel, 2017, Current protocols in chemical biology.

Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer

Heather A. Harrington, Birgit Schoeberl, Mariano Beguerisse-Díaz, 2016, Journal of the Royal Society Interface.

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

Marc Hafner, Elizabeth H. Williams, Kartik Subramanian, 2019, Cell systems.

Measuring Cancer Drug Sensitivity and Resistance in Cultured Cells

Marc Hafner, Mario Niepel, Peter K Sorger, 2017, Current protocols in chemical biology.

Receptor-Based Mechanism of Cell Memory and Relative Sensing in Mammalian Signaling Networks

Peter K. Sorger, Eugenia Lyashenko, Purushottam D. Dixit, 2017, bioRxiv.

Maximum Entropy Framework for Predictive Inference of Cell Population Heterogeneity and Responses in Signaling Networks.

Eugenia Lyashenko, Mario Niepel, Dennis Vitkup, 2019, Cell systems.

Adaptive informatics for multi-factorial and high content biological data

Mario Niepel, Peter K Sorger, Michael P Menden, 2011, Nature Methods.

Analysis of growth factor signaling in genetically diverse breast cancer lines

Marc Hafner, Birgit Schoeberl, Mario Niepel, 2014, BMC Biology.

Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics

Marc Hafner, Mario Niepel, Peter K Sorger, 2017, Nature Biotechnology.

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

Marc Hafner, Elizabeth H. Williams, Laura M. Heiser, 2017, Scientific Data.

A Cell Cycle Phosphoproteome of the Yeast Centrosome

Arend Sidow, John R. Yates, Jonathan Binkley, 2011, Science.

Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

Mohammad Fallahi-Sichani, Mario Niepel, Nathanael S Gray, 2015 .

Tensors and algebra give interpretable groups for crosstalk mechanisms in breast cancer

Heather A. Harrington, Birgit Schoeberl, Mariano Beguerisse-Díaz, 2016 .

Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines

Marc Hafner, Birgit Schoeberl, Peter K. Sorger, 2013, Science Signaling.

Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway

Peter K. Sorger, Jason E. McDermott, Carrie D. Nicora, 2016, Science Signaling.

Non-genetic Cell-to-cell Variability and the Consequences for Pharmacology This Review Comes from a Themed Issue on Omics Edited the Distribution of Protein Abundance and Resulting Variability in Phenotype Measuring Cell-to-cell Variation

Sabrina L Spencer, Mario Niepel, Peter K Sorger, 2022 .

Discovery of potent and selective covalent inhibitors of JNK.

Taebo Sim, Mario Niepel, Scott B Ficarro, 2012, Chemistry & biology.

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling

Marc Hafner, Peter K. Sorger, Todd R. Golub, 2017, Nature Communications.