C. Löwik

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Migration and phenotypic transformation of osteoclast precursors into mature osteoclasts: The effect of a bisphosphonate

G. van der Pluijm, O. Bijvoet, C. Löwik, 1988, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Role of astrocyte‐derived tissue‐type plasminogen activator in the regulation of endotoxin‐stimulated nitric oxide production by microglial cells

J. Verheijen, A. van Dam, F. Tilders, 1998, Glia.

The developmental regulation of L-ornithine decarboxylase in Dictyostelium discoideum and its induction by cAMP.

M. M. van Lookeren Campagne, C. Löwik, 1985, Biochimica et biophysica acta.

Structural requirements for bisphosphonate actions in vitro

S. Papapoulos, E. V. van Beek, M van de Ruit, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

In Vivo Molecular Bioluminescence Imaging: New Tools and Applications.

Laura Mezzanotte, Hacer Karatas, L. Mezzanotte, 2017, Trends in biotechnology.

Use of a rat model for the simultaneous assessment of pharmacokinetic and pharmacodynamic aspects of bisphosphonate treatment: Application to the study of intravenous 14C‐labeled 1‐hydroxy‐3‐(1‐pyrrolidinyl)‐propylidene‐1,1‐bisphosphonate

S. Koopmans, S. Papapoulos, L. van der Wee‐Pals, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Application of an in vitro model and a clinical protocol in the assessment of the potency of a new bisphosphonate

C. Löwik, S. Papapoulos, K. Hoekman, 1989, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Dissociation of binding and antiresorptive properties of hydroxybisphosphonates by substitution of the hydroxyl with an amino group

C. Löwik, I. Que, S. Papapoulos, 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Modulation of PTH‐stimulated osteoclastic resorption by bisphosphonates in fetal mouse bone explants

G. van der Pluijm, S. Papapoulos, M. J. Alblas, 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Two distinct effects of recombinant human tumor necrosis factor-alpha on osteoclast development and subsequent resorption of mineralized matrix.

C. Löwik, G. van der Pluijm, G. Pluijm, 1991, Endocrinology.

Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo.

E. Pieterman, C. Löwik, S. Papapoulos, 1999, Biochemical and biophysical research communications.

Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis.

L. Aarden, C. Löwik, G. van der Pluijm, 1989, Biochemical and biophysical research communications.

A frame-shift mutation in the type I parathyroid hormone (PTH)/PTH-related peptide receptor causing Blomstrand lethal osteochondrodysplasia.

P. Nijweide, P. Nijweide, M. Karperien, 1999, The Journal of clinical endocrinology and metabolism.

Sclerostin: Current Knowledge and Future Perspectives

C. Löwik, S. Papapoulos, R. Van Bezooijen, 2010, Calcified Tissue International.

Tumour progression and angiogenesis in bone metastasis from breast cancer: new approaches to an old problem.

C. Löwik, G. Pluijm, S. Papapoulos, 2000, Cancer treatment reviews.

Expression of estrogen receptors and enzymes involved in sex steroid metabolism in the rat tibia during sexual maturation.

J. Wit, M. Karperien, B. V. D. van der Eerden, 2004, The Journal of endocrinology.

Effect of interleukin-17 on nitric oxide production and osteoclastic bone resorption: is there dependency on nuclear factor-kappaB and receptor activator of nuclear factor kappaB (RANK)/RANK ligand signaling?

C. Löwik, S. Papapoulos, R. Van Bezooijen, 2001, Bone.

A two-receptor model for the action of parathyroid hormone on osteoblasts: a role for intracellular free calcium and cAMP.

J. V. van Leeuwen, C. Löwik, J. M. Meer, 1985, Cell calcium.

Interleukin 17 synergises with tumour necrosis factor α to induce cartilage destruction in vitro

C. Löwik, S. Papapoulos, R. Van Bezooijen, 2002 .

Effect of macrophage colony-stimulating factor on in vitro osteoclast generation and bone resorption.

M. Cecchini, H. Fleisch, G. van der Pluijm, 1992, Endocrinology.

Bone matrix degradation by the plasminogen activation system. Possible mechanism of bone destruction in arthritis.

H. Ronday, F. Breedveld, P. Quax, 1997, British journal of rheumatology.

Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation

C. Löwik, R. van Bezooijen, S. Papapoulos, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Sclerostin in Mineralized Matrices and van Buchem Disease

P. Hogendoorn, W. Hul, C. Löwik, 2009, Journal of dental research.

Exposure of KS483 Cells to Estrogen Enhances Osteogenesis and Inhibits Adipogenesis

M. Karperien, C. Löwik, S. Papapoulos, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Modulation of IL-6 production and IL-1 activity by keratinocyte-fibroblast interaction.

M. Ponec, L. Aarden, C. Löwik, 1993, The Journal of investigative dermatology.

Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro.

H. Vloedgraven, G. van der Pluijm, G. Pluijm, 1996, The Journal of clinical investigation.

Bone sialoprotein peptides are potent inhibitors of breast cancer cell adhesion to bone.

H. Vloedgraven, W. Grzesik, P. Robey, 1996, Cancer research.

Osteoclast formation together with interleukin-6 production in mouse long bones is increased by insulin-like growth factor-I.

C. Löwik, S. Papapoulos, L. Schot, 1992, The Journal of endocrinology.

Enhancement of the inhibitory action of APD on the transformation of osteoclast precursors into resorbing cells after dimethylation of the amino group.

P. Boonekamp, O. Bijvoet, C. Löwik, 1987, Bone and mineral.

J. Reeve, C. Löwik, K. Poole, 2022 .

Effect of alendronate treatment on the osteoclastogenic potential of bone marrow cells in mice.

C. Löwik, S. Papapoulos, E. V. van Beek, 1997, Bone.

Differential Effects of Aminosubstituted Analogs of Hydroxy Bisphosphonates on the Growth of Dictyostelium discoideum

S. Papapoulos, D. Watts, E. V. Beek, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Binding and antiresorptive properties of heterocycle-containing bisphosphonate analogs: structure-activity relationships.

C. Löwik, F. H. Ebetino, S. Papapoulos, 1998, Bone.

The use of bisphosphonates in the treatment of osteoporosis.

R. Valkema, E. Pauwels, C. Löwik, 1992, Bone.

Quantification of adherent and nonadherent cells cultured in 96-well plates using the supravital stain neutral red.

C. Löwik, G. van der Pluijm, S. Papapoulos, 1993, Analytical biochemistry.

Inhibition of Gsk3β in cartilage induces osteoarthritic features through activation of the canonical Wnt signaling pathway.

J. Goeman, L. Finos, J. Wit, 2011, Osteoarthritis and cartilage.

The Role of Sclerostin in the Pathophysiology of Sclerosing Bone Dysplasias

C. Löwik, S. Papapoulos, N. Hamdy, 2012, Clinical Reviews in Bone and Mineral Metabolism.

Differentiating the mechanisms of antiresorptive action of nitrogen containing bisphosphonates.

C. Löwik, S. Papapoulos, F. Ebetino, 2003, Bone.