P. Chaignon

发表

The Reductive Dehydroxylation Catalyzed by IspH, a Source of Inspiration for the Development of Novel Anti-Infectives

F. Borel, M. Seemann, G. Bianchino, 2022, Molecules.

Methylerythritol Phosphate Pathway: Enzymatic Evidence for a Rotation in the LytB/IspH Catalyzed Reaction.

M. Seemann, L. Allouche, B. Vincent, 2019, Chemistry.

Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New Antimicrobials

J. Ferrer, C. Poulter, F. Borel, 2017, Chembiochem : a European journal of chemical biology.

Susceptibility of staphylococcal biofilms to enzymatic treatments depends on their chemical composition

J. Kaplan, I. Sadovskaya, N. Ramasubbu, 2007, Applied Microbiology and Biotechnology.

Carbohydrate-containing components of biofilms produced in vitro by some staphylococcal strains related to orthopaedic prosthesis infections.

I. Sadovskaya, G. Kogan, Evgeny Vinogradov, 2006, FEMS immunology and medical microbiology.

Purification and identification of a Bacillus nitroreductase : Potential use in 3,5-DNBTF biosensoring system

F. Halgand, J. Ouazzani, O. Laprévote, 2006 .

Dehydrogenation, oxidative denitration and ring contraction of N,N-dimethyl-5-nitrouracil by a Bacillus nitroreductase Nfr-A1

J. Ouazzani, S. Dézard, D. Sergent, 2012 .

NADH oxidase activity of Bacillus subtilis nitroreductase NfrA1: Insight into its biological role

Philippe Chaignon, Stéphane Aymerich, Philippe Meyer, 2010, FEBS letters.

Isoprenoid Biosynthesis in Pathogenic Bacteria: Nuclear Resonance Vibrational Spectroscopy Provides Insight into the Unusual [4Fe-4S] Cluster of the E. coli LytB/IspH Protein.

C. Poulter, I. Faus, J. Wolny, 2015, Angewandte Chemie.

Inhibition of IspH, a [4Fe-4S]2+ enzyme involved in the biosynthesis of isoprenoids via the methylerythritol phosphate pathway.

C. Poulter, M. Rohmer, M. Seemann, 2013, Journal of the American Chemical Society.

Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD

J. Ferrer, A. Wagner, F. Borel, 2018, Scientific Reports.

Photochemical Reactivity of Trifluoromethyl Aromatic Amines: The Example of 3,5-diamino-trifluoromethyl-benzene (3,5-DABTF)

V. Guérineau, J. Ouazzani, M. Adeline, 2005, Photochemistry and Photobiology.

Biofilms of clinical strains of Staphylococcus that do not contain polysaccharide intercellular adhesin.

I. Sadovskaya, G. Kogan, S. Jabbouri, 2006, FEMS microbiology letters.

Inhibition of IspH, a [4Fe-4S]2+ enzyme involved in the biosynthesis of isoprenoids via the methylerythritol phosphate pathway.

M. Rohmer, M. Seemann, Sergiy G. Krasutsky, 2013, Journal of the American Chemical Society.

Synthesis and kinetic evaluation of analogs of (E)-4-amino-3-methylbut-2-en-1-yl diphosphate, a potent inhibitor of the IspH metalloenzyme

Hannah Jobelius, P. Chaignon, Benoît Eric Petit, 2023, Comptes Rendus. Chimie.

Carbohydrate-Templated Syntheses of Trifluoromethyl-Substituted MEP Analogues for the Study of the Methylerythritol Phosphate Pathway.

J. Behr, P. Chaignon, Jean-Luc Vasse, 2023, The Journal of organic chemistry.