Calvin Yu‐Chian Chen

发表

Drug Design for Neuropathic Pain Regulation from Traditional Chinese Medicine

Su-Sen Chang, Calvin Yu-Chian Chen, Weng Ieong Tou, 2013, Scientific Reports.

What is the Effective Component in Suanzaoren Decoction for Curing Insomnia? Discovery by Virtual Screening and Molecular Dynamic Simulation

Calvin Yu-Chian Chen, Chieh-Hsi Wu, H. Tsai, 2008, Journal of biomolecular structure & dynamics.

Potent Inhibitor Design Against H1N1 Swine Influenza: Structure-based and Molecular Dynamics Analysis for M2 Inhibitors from Traditional Chinese Medicine Database

Hsin-Yi Chen, F. Tsai, Tung-Ti Chang, 2011, Journal of biomolecular structure & dynamics.

Traditional Chinese medicine as dual guardians against hypertension and cancer?

Calvin Yu-Chian Chen, W. Tou, Calvin Yu‐Chian Chen, 2012, Journal of biomolecular structure & dynamics.

Residue-based design of small molecule inhibitor for H1N1, H5N1 and H7N1 mutants

Calvin Yu-Chian Chen, Tung-Ti Chang, Cheng-Chun Lee, 2015, Journal of Molecular Modeling.

Drug Design of Cyclin-Dependent Kinase 2 Inhibitor for Melanoma from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hsin-Chieh Tang, Calvin Yu‐Chian Chen, 2014, BioMed research international.

Drug design for hemagglutinin: Screening and molecular dynamics from traditional Chinese medicine database

Calvin Yu-Chian Chen, Hsin-Yi Chen, F. Tsai, 2011 .

VAERHNN: Voting-averaged ensemble regression and hybrid neural network to investigate potent leads against colorectal cancer

Qiujie Lv, Zihuan Yang, Xuefei Jiang, 2022, Knowl. Based Syst..

A Novel Graph Neural Network Methodology to Investigate Dihydroorotate Dehydrogenase Inhibitors in Small Cell Lung Cancer

Cheng-Chun Lee, Lu Zhao, Calvin Yu‐Chian Chen, 2021, Biomolecules.

Insight into potent leads for alzheimer's disease by using several artificial intelligence algorithms.

Calvin Yu-Chian Chen, Hsin-Yi Chen, Lu Zhao, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Artificial Intelligence Approach To Investigate the Longevity Drug.

Calvin Yu-Chian Chen, Hsin-Yi Chen, Jun-Yan Li, 2019, The journal of physical chemistry letters.

Three-in-one agonists for PPAR-α, PPAR-γ, and PPAR-δ from traditional Chinese medicine

Tu-Liang Lin, Yongjiang Wu, Hung-Jin Huang, 2012, Journal of biomolecular structure & dynamics.

Investigation of the Novel Lead of Melanocortin 1 Receptor for Pigmentary Disorders

Calvin Yu-Chian Chen, Hsin-Chieh Tang, Calvin Yu‐Chian Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

Network pharmacology-based approach of novel traditional Chinese medicine formula for treatment of acute skin inflammation in silico

Calvin Yu-Chian Chen, Hung-Jin Huang, Cheng-Chun Lee, 2017, Comput. Biol. Chem..

Identifying HER2 Inhibitors from Natural Products Database

Calvin Yu-Chian Chen, Su-Sen Chang, Shun-Chieh Yang, 2011, PloS one.

Screening from TCM Database@Taiwan and QSAR model for identifying HER2 inhibitors

Calvin Yu-Chian Chen, Kai-Wei Chang, Hsin-Yi Chen, 2011 .

TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2011, PloS one.

In Silico Investigation of Potential TRAF6 Inhibitor from Traditional Chinese Medicine against Cancers

Calvin Yu-Chian Chen, Hsin-Yi Chen, Kuan-Chung Chen, 2014, BioMed research international.

Screening from the world's largest TCM database for inhibiting DNA repair protein XRCC4

Kai-Wei Chang, Hsin-Yi Chen, Jaung-Geng Lin, 2011 .

In Silico Investigation of Potential Src Kinase Ligands from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Weng Ieong Tou, W. Tou, 2012, PloS one.

Han ethnicity-specific type 2 diabetic treatment from traditional Chinese medicine?

Su-Sen Chang, Fuu-Jen Tsai, Calvin Yu-Chian Chen, 2013, Journal of biomolecular structure & dynamics.

Computational screening and QSAR analysis for design of AMP-activated protein kinase agonist

Hsin-Yi Chen, F. Tsai, Hung-Jin Huang, 2010 .

Drug Design for AMP-Activated Protein Kinase Agonists in Silico

Calvin Yu-Chian Chen, Hung-Jin Huang, Chien-Yu Chen, 2009, 2009 2nd International Conference on Biomedical Engineering and Informatics.

Lead Screening for Chronic Obstructive Pulmonary Disease of IKK2 Inhibited by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Yung-An Tsou, Hung-Jin Huang, 2014, Evidence-based complementary and alternative medicine : eCAM.

Predicting Drug-Target Interactions with Deep-Embedding Learning of Graphs and Sequences.

Lu Zhao, Guanxing Chen, Calvin Yu‐Chian Chen, 2021, The journal of physical chemistry. A.

A novel artificial intelligence protocol for finding potential inhibitors of acute myeloid leukemia.

Calvin Yu-Chian Chen, Xu Chen, Hsin-Yi Chen, 2020, Journal of materials chemistry. B.

Identification of Potent EGFR Inhibitors from TCM Database@Taiwan

Calvin Yu-Chian Chen, Su-Sen Chang, Hsin-Yi Chen, 2011, PLoS Comput. Biol..

Weighted Equation and Rules—A Novel Concept for Evaluating Protein-Ligand Interaction

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2009, Journal of biomolecular structure & dynamics.

What is the Key Point for Designing HER2 Inhibitors?

Calvin Yu-Chian Chen, Hung-Jin Huang, Chien-Yu Chen, 2009, 2009 2nd International Conference on Biomedical Engineering and Informatics.

Artificial Intelligence Approach to Find Lead Compounds for Treating Tumors.

Calvin Yu-Chian Chen, Hsin-Yi Chen, Jian-Qiang Chen, 2019, The journal of physical chemistry letters.

Treatment of Acute Lymphoblastic Leukemia from Traditional Chinese Medicine

Pei-Chun Chang, Hung-Jin Huang, Chia-Chen Kuo, 2014, Evidence-based complementary and alternative medicine : eCAM.

An Investigation of Small GTPases in relation to Liver Tumorigenesis Using Traditional Chinese Medicine

Calvin Yu-Chian Chen, Kuen-Bao Chen, Wen-Yuan Lee, 2014, BioMed research international.

Insight into HIV of IFN-Induced Myxovirus Resistance 2 (MX2) Expressed by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Kuen-Bao Chen, Wen-Yuan Lee, 2014, BioMed research international.

Lead Screening for CXCR4 of the Human HIV Infection Receptor Inhibited by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Kuen-Bao Chen, Wen-Yuan Lee, 2014, BioMed research international.

Lead Screening for HIV of C-C Chemokine Receptor Type 5 Receptor Inhibited by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hung-Jin Huang, Kuen-Bao Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

Discovery of novel insomnia leads from screening traditional Chinese medicine database

Calvin Yu-Chian Chen, Hsin-Yi Chen, Su-Sen Chang, 2014, Journal of biomolecular structure & dynamics.

In Silico Investigation of Potential PARP-1 Inhibitors from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Mao-Feng Sun, Kuan-Chung Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

Design of Glucagon-Like Peptide-1 Receptor Agonist for Diabetes Mellitus from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hsin-Chieh Tang, Calvin Yu‐Chian Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

Osteoponin Promoter Controlled by DNA Methylation: Aberrant Methylation in Cloned Porcine Genome

Calvin Yu-Chian Chen, Yung-An Tsou, S. Wu, 2014, BioMed research international.

Lead Discovery for Alzheimer's Disease Related Target Protein RbAp48 from Traditional Chinese Medicine

Hung-Jin Huang, Calvin Yu-Chian Chen, Hung-Jin Huang, 2014, BioMed research international.

Memory enhancement by traditional Chinese medicine?

Pei-Chun Chang, Su-Sen Chang, Cheng-Chun Lee, 2013, Journal of biomolecular structure & dynamics.

How to design a drug for the disordered proteins?

Calvin Yu-Chian Chen, Weng Ieong Tou, W. Tou, 2013, Drug discovery today.

Evaluation of Correlation of Cell Cycle Proteins and Ki-67 Interaction in Paranasal Sinus Inverted Papilloma Prognosis and Squamous Cell Carcinoma Transformation

Yung-An Tsou, Chuan‐Mu Chen, Chih-Jaan Tai, 2014, BioMed research international.

Ligand-Based and Structure-Based Investigation for Alzheimer's Disease from Traditional Chinese Medicine

Calvin Yu-Chian Chen, K. Liao, Mao-Feng Sun, 2014, Evidence-based complementary and alternative medicine : eCAM.

Potential Mitochondrial Isocitrate Dehydrogenase R140Q Mutant Inhibitor from Traditional Chinese Medicine against Cancers

Calvin Yu-Chian Chen, Hsin-Yi Chen, Kuan-Chung Chen, 2014, BioMed research international.

In Silico Insight into Potent of Anthocyanin Regulation of FKBP52 to Prevent Alzheimer's Disease

Calvin Yu-Chian Chen, M. Fan, Tung-Ti Chang, 2014, Evidence-based complementary and alternative medicine : eCAM.

Potential Protein Phosphatase 2A Agents from Traditional Chinese Medicine against Cancer

Kuan-Chung Chen, Calvin Yu-Chian Chen, Hsin-Yi Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

Potential Protein Phosphatase 2 A Agents from Traditional Chinese Medicine against Cancer Citation

Calvin Yu-Chian Chen, Hsin-Yi Chen, Kuan-Chung Chen, 2014 .

Phenylphthalazines as small-molecule inhibitors of urea transporter UT-B and their binding model

Calvin Yu-Chian Chen, Hong Zhou, Tian-luo Lei, 2016, Acta Pharmacologica Sinica.

Lose Weight with Traditional Chinese Medicine? Potential Suppression of Fat Mass and Obesity-Associated Protein

Calvin Yu-Chian Chen, Kai-Wei Chang, F. Tsai, 2011, Journal of biomolecular structure & dynamics.

Key Features for Designing Phosphodiesterase-5 Inhibitors

Hung-Jin Huang, Hsin Wei Yu, Kuei-Jen Lee, 2010, Journal of biomolecular structure & dynamics.

Virtual Screening and Drug Design for PDE-5 Receptor from Traditional Chinese Medicine Database

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2010, Journal of biomolecular structure & dynamics.

Screening from the World's Largest TCM Database Against H1N1 Virus

Calvin Yu-Chian Chen, Hsin-Yi Chen, F. Tsai, 2011, Journal of biomolecular structure & dynamics.

Novel and versatile artificial intelligence algorithms for investigating possible GHSR1α and DRD1 agonists for Alzheimer's disease

Lu Zhao, Guanxing Chen, Calvin Yu‐Chian Chen, 2021, RSC advances.

Search for Novel Remedies to Augment Radiation Resistance of Inhabitants of Fukushima and Chernobyl Disasters: Identifying DNA Repair Protein XRCC4 Inhibitors

Calvin Yu-Chian Chen, Hsin-Yi Chen, F. Tsai, 2011, Journal of biomolecular structure & dynamics.

Structure-Based and Ligand-Based Drug Design for HER 2 Receptor

Hung-Jin Huang, Chien-Yu Chen, Kuei-Jen Lee, 2010, Journal of biomolecular structure & dynamics.

Drug discovery for DNA break repair system by screening from TCM database and molecular dynamics approach

Hsin-Yi Chen, F. Tsai, Tung-Ti Chang, 2011 .

Blocking the DNA Repair System by Traditional Chinese Medicine?

Kai-Wei Chang, Hsin-Yi Chen, F. Tsai, 2011, Journal of biomolecular structure & dynamics.

Treatment of Rheumatoid Arthritis with Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hsin-Yi Chen, Kuan-Chung Chen, 2014, BioMed research international.

Drug Design for XRCC4 in Silico

Calvin Yu-Chian Chen, Jing-Gung Chung, Hung-Jin Huang, 2009, 2009 2nd International Conference on Biomedical Engineering and Informatics.

May disordered protein cause serious drug side effect?

Calvin Yu-Chian Chen, W. Tou, Calvin Yu‐Chian Chen, 2014, Drug discovery today.

Clinical Named Entity Recognition using Contextualized Token Representations pdf

Wei Wang, Kevin J. Shih, J. Harry Caufield, 2021, ArXiv.

TCMBank-the largest TCM database provides deep learning-based Chinese-Western medicine exclusion prediction

Qiujie Lv, Lu Zhao, Ziduo Yang, 2023, Signal Transduction and Targeted Therapy.

ML-DTI: Mutual Learning Mechanism for Interpretable Drug-Target Interaction Prediction.

Weihe Zhong, Calvin Yu-Chian Chen, Lu Zhao, 2021, The journal of physical chemistry letters.

Pharmacological Chaperone Design for Reducing Risk Factor of Parkinson's Disease from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hung-Jin Huang, Cheng-Chun Lee, 2014, Evidence-based complementary and alternative medicine : eCAM.

A possible strategy against head and neck cancer: in silico investigation of three-in-one inhibitors

Calvin Yu-Chian Chen, Yung-An Tsou, Kuan-Chung Chen, 2013, Journal of biomolecular structure & dynamics.

Investigation of silent information regulator 1 (Sirt1) agonists from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Tung-Ti Chang, Mao-Feng Sun, 2013, Journal of biomolecular structure & dynamics.

Uroporphyrinogen Decarboxylase as a Potential Target for Specific Components of Traditional Chinese Medicine: A Virtual Screening and Molecular Dynamics Study

Calvin Yu-Chian Chen, Yung-An Tsou, Kuan-Chung Chen, 2012, PloS one.

Treat Alzheimer's disease by traditional Chinese medicine?

Kai-Wei Chang, Hsin-Yi Chen, F. Tsai, 2011 .

In Silico Investigation of Cytochrome P450 2C9 in relation to Aging Using Traditional Chinese Medicine

Calvin Yu-Chian Chen, Tzu-Chieh Hung, Chia-Chen Kuo, 2014, Evidence-based complementary and alternative medicine : eCAM.

Pharmacoinformatics approach for mPGES-1 in anti-inflammation by 3D-QSAR pharmacophore mapping

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2009 .

Exploring 3D-QSAR pharmacophore mapping of azaphenanthrenone derivatives for mPGES-1 inhibition Using HypoGen technique

Winston Yu-Chen Chen, Po-Yuan Chen, Calvin Yu-Chian Chen, 2008, 2008 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology.

Chemoinformatics and pharmacoinformatics approach for exploring the GABA-A agonist from Chinese herb suanzaoren

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2009 .

iSMART: An Integrated Cloud Computing Web Server for Traditional Chinese Medicine for Online Virtual Screening, de novo Evolution and Drug Design

Kai-Wei Chang, Calvin Yu-Chian Chen, Hung-Jin Huang, 2011, Journal of biomolecular structure & dynamics.

iScreen: world’s first cloud-computing web server for virtual screening and de novo drug design based on TCM database@Taiwan

Kai-Wei Chang, Calvin Yu-Chian Chen, Tsung-Ying Tsai, 2011, J. Comput. Aided Mol. Des..

Finding Inhibitors of Mutant Superoxide Dismutase-1 for Amyotrophic Lateral Sclerosis Therapy from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hsin-Yi Chen, Tung-Ti Chang, 2014, Evidence-based complementary and alternative medicine : eCAM.

In Silico Identification of Potent Pancreatic Triacylglycerol Lipase Inhibitors from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Kuan-Yu Chen, Su-Sen Chang, 2012, PloS one.

Novel hemagglutinin inhibitors for H1N1 influenza virus screening from TCM database

Hsin-Yi Chen, F. Tsai, Jaung-Geng Lin, 2011 .

Application of bioactivity database of Chinese herbal medicine on the therapeutic prediction, drug development, and safety evaluation.

Hsin-Yi Lo, Chia-Cheng Li, T. Ho, 2010, Journal of ethnopharmacology.

Could Traditional Chinese Medicine Used for Curing Erectile Dysfunction?

Calvin Yu-Chian Chen, Hung-Jin Huang, Chien-Yu Chen, 2009, 2009 2nd International Conference on Biomedical Engineering and Informatics.

Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis

Calvin Yu-Chian Chen, Chien-Yu Chen, F. Tsai, 2009, Acta Pharmacologica Sinica.

Computational Design of Apolipoprotein E4 Inhibitors for Alzheimer's Disease Therapy from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hsin-Yi Chen, Hung-Jin Huang, 2014, BioMed research international.

Insight into two antioxidants binding to the catalase NADPH binding site from traditional Chinese medicines

Calvin Yu-Chian Chen, Hsin-Yi Chen, Hung-Jin Huang, 2015 .

Deep Learning and Random Forest Approach for Finding the Optimal Traditional Chinese Medicine Formula for Treatment of Alzheimer's Disease

Xi Chen, Calvin Yu-Chian Chen, Hung-Jin Huang, 2019, J. Chem. Inf. Model..

Treatment of Cardiovascular Disease by Traditional Chinese Medicine against Pregnane X Receptor

Calvin Yu-Chian Chen, Hsin-Yi Chen, Kuan-Chung Chen, 2014, BioMed research international.

Potential Smoothened Inhibitor from Traditional Chinese Medicine against the Disease of Diabetes, Obesity, and Cancer

Calvin Yu-Chian Chen, Hsin-Yi Chen, Mao-Feng Sun, 2014, BioMed research international.

In Silico Investigation of Potential Pyruvate Kinase M2 Regulators from Traditional Chinese Medicine against Cancers

Calvin Yu-Chian Chen, Hsin-Yi Chen, Kuan-Chung Chen, 2014, BioMed research international.

In Silico Investigation of Potential mTOR Inhibitors from Traditional Chinese Medicine for Treatment of Leigh Syndrome

Hsin-Yi Chen, Wen-Yuan Lee, Kuan-Chung Chen, 2014, BioMed research international.

In Silico Identification of Potent PPAR-γ Agonists from Traditional Chinese Medicine: A Bioactivity Prediction, Virtual Screening, and Molecular Dynamics Study

Calvin Yu-Chian Chen, Kuan-Chung Chen, Kuan-Chung Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

Lung Lesion Localization of COVID-19 From Chest CT Image: A Novel Weakly Supervised Learning Method

Shuyu Wu, Lu Zhao, Ziduo Yang, 2021, IEEE Journal of Biomedical and Health Informatics.

Traditional Chinese medicine application in HIV: an in silico study

Hung-Jin Huang, Yi-Ru Jian, Calvin Yu‐Chian Chen, 2014, Journal of biomolecular structure & dynamics.

A novel integrated framework and improved methodology of computer-aided drug design.

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2013, Current topics in medicinal chemistry.

Dynamic concept-aware network for few-shot learning

Calvin Yu-Chian Chen, Qiujie Lv, Jun Zhou, 2022, Knowl. Based Syst..

Current developments of computer-aided drug design

Chien-Yu Chen, Hsin Wei Yu, Calvin Yu-Chian Chen, 2010 .

Mechanism of BAG1 repair on Parkinson’s disease-linked DJ1 mutation

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2012, Journal of biomolecular structure & dynamics.

A novel artificial intelligence protocol to investigate potential leads for Parkinson's disease

Hsin-Yi Chen, Lu Zhao, Zhidong Chen, 2020, RSC advances.

Two Birds with One Stone? Possible Dual-Targeting H1N1 Inhibitors from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Su-Sen Chang, Hung-Jin Huang, 2011, PLoS Comput. Biol..

Two Birds with One Stone ? Possible Dual-Targeting H 1 N 1 Inhibitors from Traditional Chinese Medicine

Su-Sen Chang, Hung-Jin Huang, Calvin Yu-Chian Chen, 2011 .

Insights into the suanzaoren mechanism—From constructing the 3D structure of GABA-A receptor to its binding interaction analysis

Calvin Yu‐Chian Chen, 2008 .

A Novel Perspective on Designing the Inhibitor of HER2 Receptor

Calvin Yu‐Chian Chen, 2008 .

Lead Screening for HIV-1 Integrase (IN) Inhibited by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Kuen-Bao Chen, Wen-Yuan Lee, 2014, BioMed research international.

Molecular dynamics analysis of potent inhibitors of M2 proton channel against H1N1 swine influenza virus

Hsin-Yi Chen, Jaung-Geng Lin, Tung-Ti Chang, 2011 .

Investigation into Potent Inflammation Inhibitors from Traditional Chinese Medicine

Hsin-Yi Chen, F. Tsai, Mao-Feng Sun, 2011, Chemical biology & drug design.

In silico pharmacology suggests ginger extracts may reduce stroke risks.

Calvin Yu-Chian Chen, Kai-Wei Chang, Hsin-Yi Chen, 2011, Molecular bioSystems.

Traditional Chinese medicine, a solution for reducing dual stroke risk factors at once?

Kuan-Chung Chen, Calvin Yu-Chian Chen, Kai-Wei Chang, 2011, Molecular bioSystems.

Potential Retinoid X Receptor Agonists for Treating Alzheimer's Disease from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Yu-Cheng Liu, Kuan-Chung Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

Investigation of Anti-Infection Mechanism of Lactoferricin and Splunc-1

Calvin Yu-Chian Chen, Yung-An Tsou, Hung-Jin Huang, 2014, Evidence-based complementary and alternative medicine : eCAM.

Adaptive boost approach for possible leads of triple-negative breast cancer

Calvin Yu-Chian Chen, Kuen-Bao Chen, Lu Zhao, 2022, Chemometrics and Intelligent Laboratory Systems.

In Silico Design for Adenosine Monophosphate-Activated Protein Kinase Agonist from Traditional Chinese Medicine for Treatment of Metabolic Syndromes

Calvin Yu-Chian Chen, Hsin-Chieh Tang, Calvin Yu‐Chian Chen, 2014, Evidence-based complementary and alternative medicine : eCAM.

3D graph neural network with few-shot learning for predicting drug-drug interactions in scaffold-based cold start scenario

Qiujie Lv, Ziduo Yang, Jun Zhou, 2023, Neural Networks.

Combining Molecular Docking and Graph Convolutional Network to Discover Potential Selective Limk1 Inhibitors

Calvin Yu-Chian Chen, Lu Zhao, Weihe Zhong, 2021 .

Artificial Intelligence-Based Application to Explore Inhibitors of Neurodegenerative Diseases

Calvin Yu-Chian Chen, Xuedong He, Leping Deng, 2020, Frontiers in Neurorobotics.

A possible solution for hair loss by inhibiting corticotropin-releasing factor (CRF) receptor from traditional Chinese medicine

Hung-Jin Huang, Calvin Yu‐Chian Chen, 2014, Journal of biomolecular structure & dynamics.

Discovery of Novel Inhibitors for c-Met by Virtual Screening and Pharmacophore Analysis

Calvin Yu‐Chian Chen, 2008 .

A Novel Algorithm for Identification of Activated Cryptic 5′ Splice Sites

Calvin Yu-Chian Chen, Guang-Wu Chen, Kun-Nan Tsai, 2012, Journal of biomolecular structure & dynamics.

Hybrid neural network approaches to predict drug–target binding affinity for drug repurposing: screening for potential leads for Alzheimer’s disease

Guanxing Chen, Calvin Yu‐Chian Chen, Xialin Wu, 2023, Frontiers in Molecular Biosciences.

Retrosynthesis prediction using an end-to-end graph generative architecture for molecular graph editing

Ziduo Yang, Weihe Zhong, Calvin Yu‐Chian Chen, 2023, Nature communications.

Learning object-uncertainty policy for visual tracking

Xuedong He, Calvin Yu-Chian Chen, Xuedong He, 2022, Inf. Sci..

In Silico Investigation of Traditional Chinese Medicine Compounds to Inhibit Human Histone Deacetylase 2 for Patients with Alzheimer's Disease

Tzu-Chieh Hung, Wen-Yuan Lee, Calvin Yu-Chian Chen, 2014, BioMed research international.

A Novel Strategy for Designing the Selective PPAR Agonist by the “Sum of Activity” Model

Hung-Jin Huang, Hsin Wei Yu, Kuei-Jen Lee, 2010, Journal of biomolecular structure & dynamics.

Insights into designing the dual-targeted HER2/HSP90 inhibitors.

Chien-Yu Chen, Calvin Yu-Chian Chen, Chien-Yu Chen, 2010, Journal of molecular graphics & modelling.

Bioinformatics, chemoinformatics, and pharmainformatics analysis of HER2/HSP90 dual-targeted inhibitors

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2010 .

Ligand-Based Dual Target Drug Design for H1N1: Swine Flu- A Preliminary First Study

Hung-Jin Huang, Chien-Yu Chen, Da-Tian Bau, 2009, Journal of biomolecular structure & dynamics.

Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5.

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2009, Journal of molecular graphics & modelling.

Machine learning and graph neural network for finding potential drugs related to multiple myeloma

Guanxing Chen, Haohuai He, Calvin Yu‐Chian Chen, 2022, New Journal of Chemistry.

Dual-Targeted Drug Design of HER2 and HSP90 by CoMFA Model and Pharmacophore Analysis

Calvin Yu-Chian Chen, Hung-Jin Huang, Chien-Yu Chen, 2009, 2009 2nd International Conference on Biomedical Engineering and Informatics.

A Network Pharmacology-Based Approach to Investigate the Novel TCM Formula against Huntington's Disease and Validated by Support Vector Machine Model

Calvin Yu-Chian Chen, Hsin-Yi Chen, Wenjie Dai, 2018, Evidence-based complementary and alternative medicine : eCAM.

CARes‐UNet: Content‐aware residual UNet for lesion segmentation of COVID‐19 from chest CT images

Calvin Yu-Chian Chen, Youjun Zhao, Xinhua Xu, 2021, Medical physics.

Molecular Simulation of HER2/neu Degradation by Inhibiting HSP90

Winston Yu-Chen Chen, Calvin Yu‐Chian Chen, Guan-Wen Chen, 2008 .

Structure-based and ligand-based drug design for microsomal prostaglandin E synthase-1 inhibitors

Calvin Yu-Chian Chen, Hsin-Yi Chen, F. Tsai, 2011 .

In Silico Design of BACE1 Inhibitor for Alzheimer's Disease by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hung-Jin Huang, Cheng-Chun Lee, 2014, BioMed research international.

In Silico Design of BACE 1 Inhibitor for Alzheimer ’ s Disease by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Hung-Jin Huang, Cheng-Chun Lee, 2015 .

The Inhibition of Folylpolyglutamate Synthetase (folC) in the Prevention of Drug Resistance in Mycobacterium tuberculosis by Traditional Chinese Medicine

Calvin Yu-Chian Chen, Kuen-Bao Chen, Wen-Yuan Lee, 2014, BioMed research international.

WITHDRAWN: DrugPrinter: print any drug instantly.

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2014, Drug discovery today.

A Multi-Task Group Bi-LSTM Networks Application on Electrocardiogram Classification

Calvin Yu-Chian Chen, Yingying Wang, Lianxin Qi, 2019, IEEE Journal of Translational Engineering in Health and Medicine.

Attention fusion and target-uncertain detection for discriminative tracking

Xuedong He, Calvin Yu‐Chian Chen, 2023, Knowl. Based Syst..

FusionDTA: attention-based feature polymerizer and knowledge distillation for drug-target binding affinity prediction

Guanxing Chen, Calvin Yu‐Chian Chen, Weining Yuan, 2021, Briefings Bioinform..

Enhancing discriminative appearance model for visual tracking

Xuedong He, Calvin Yu‐Chian Chen, 2023, Expert Syst. Appl..

Exploring reliable visual tracking via target embedding network

Xuedong He, Calvin Yu‐Chian Chen, 2022, Knowl. Based Syst..

Variable scale learning for visual object tracking

Xuedong He, Calvin Yu-Chian Chen, Lu Zhao, 2021, Journal of Ambient Intelligence and Humanized Computing.

Capsule-Encoder-Decoder: A Method for Generalizable Building Extraction from Remote Sensing Images

Zhenchao Tang, Zhiming Hong, Weiran Luo, 2022, Remote. Sens..

In Silico Investigation of Potential Pyruvate Kinase M2 Regulators from Traditional Chinese Medicine against Cancers

Hsin-Yi Chen, Kuan-Chung Chen, Calvin Yu‐Chian Chen, 2014, BioMed Research International.

In Silico Investigation of Potential mTOR Inhibitors from Traditional Chinese Medicine for Treatment of Leigh Syndrome

Hsin-Yi Chen, Wen-Yuan Lee, Kuan-Chung Chen, 2014, BioMed Research International.

Study of AMP-Activated Protein Kinase Agonists by Structure-Based Drug Designing

Calvin Yu-Chian Chen, Chieh-Hsi Wu, Chien-Yu Chen, 2009 .

Stroke prevention by traditional Chinese medicine? A genetic algorithm, support vector machine and molecular dynamics approach

Kuan-Chung Chen, Calvin Yu-Chian Chen, Kuan-Chung Chen, 2011 .

GINCM-DTA: A graph isomorphic network with protein contact map representation for potential use against COVID-19 and Omicron subvariants BQ.1, BQ.1.1, XBB.1.5, XBB.1.16

Qiujie Lv, Lu Zhao, Guanxing Chen, 2023, Expert Systems with Applications.

Weakly Supervised Posture Mining for Fine-Grained Classification

Hua-Bin Yang, Calvin Yu‐Chian Chen, Zhenchao Tang, 2023, 2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR).

De novo design of novel selective COX-2 inhibitors: From virtual screening to pharmacophore analysis

Calvin Yu-Chian Chen, Calvin Yu‐Chian Chen, 2009 .

Reducing without Side Effects? A Novel Strategy for Designing the PPAR Agonists

Calvin Yu-Chian Chen, Hung-Jin Huang, Chien-Yu Chen, 2009, 2009 2nd International Conference on Biomedical Engineering and Informatics.

Investigation of Estrogen Receptor (ESR1) for Breast Cancer from Traditional Chinese Medicine

Calvin Yu-Chian Chen, Kuen-Bao Chen, Wen-Yuan Lee, 2014, BioMed research international.

High performance screening, structural and molecular dynamics analysis to identify H1 inhibitors from TCM Database@Taiwan.

Hung-Jin Huang, Su-Sen Chang, Calvin Yu‐Chian Chen, 2011, Molecular bioSystems.

A novel artificial intelligence protocol to investigate potential leads for diabetes mellitus

Lu Zhao, Zhidong Chen, Jia-Ning Gong, 2021, Molecular Diversity.

Meta Learning With Graph Attention Networks for Low-Data Drug Discovery.

Qiujie Lv, Ziduo Yang, Weihe Zhong, 2023, IEEE transactions on neural networks and learning systems.

Enhancing adversarial defense for medical image analysis systems with pruning and attention mechanism.

Calvin Yu‐Chian Chen, Lun Chen, Lu Zhaoa, 2021, Medical physics.

Cascading residual–residual attention generative adversarial network for image super resolution

Yali Zhang, Calvin Yu‐Chian Chen, Jianqiang Chen, 2021, Soft Comput..

Research Article in Silico Identification of Potent Ppar-í Μí»¾ Agonists from Traditional Chinese Medicine: a Bioactivity Prediction, Virtual Screening, and Molecular Dynamics Study

Kuan-Chung Chen, Calvin Yu‐Chian Chen, Yu-Chian Calvin, 2022 .

In silico pharmacology suggests ginger extracts may reduce stroke risks.

Kai-Wei Chang, Hsin-Yi Chen, F. Tsai, 2011, Molecular bioSystems.

NHGNN-DTA: a node-adaptive hybrid graph neural network for interpretable drug–target binding affinity prediction

Guanxing Chen, Haohuai He, Calvin Yu‐Chian Chen, 2023, Bioinformatics.

A Novel Strategy for Designing Dual-Target Inhibitors of KU86 and XRCC4

Calvin Yu-Chian Chen, Jing-Gung Chung, Hung-Jin Huang, 2009, 2009 2nd International Conference on Biomedical Engineering and Informatics.

iScreen: world’s first cloud-computing web server for virtual screening and de novo drug design based on TCM database@Taiwan

Kai-Wei Chang, Calvin Yu‐Chian Chen, Tsung-Ying Tsai, 2011, J. Comput. Aided Mol. Des..

Developing Hypothetical Inhibition Mechanism of Novel Urea Transporter B Inhibitor

Baoxue Yang, Hong Zhou, Huiwen Ren, 2014, Scientific Reports.

How to design a drug for the disordered proteins?

W. Tou, Calvin Yu‐Chian Chen, 2013, Drug discovery today.