Ya-Ming Xu

发表

Selective Toxicity of Secondary Metabolites from the Entomopathogenic Bacterium Photorhabdus luminescens sonorensis against Selected Plant Parasitic Nematodes of the Tylenchina Suborder

I. Molnár, S. Stock, Ya-ming Xu, 2022, Microbiology spectrum.

Intrinsic and Extrinsic Programming of Product Chain Length and Release Mode in Fungal Collaborating Iterative Polyketide Synthases.

Xiaoyi Wei, I. Molnár, A. Gunatilaka, 2020, Journal of the American Chemical Society.

Rational Reprogramming of O-Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds

Wei Zhang, Ming Chen, Min Lin, 2019, Journal of the American Chemical Society.

Diversity-Oriented Combinatorial Biosynthesis of Hybrid Polyketide Scaffolds from Azaphilone and Benzenediol Lactone Biosynthons.

Wei Zhang, Ming Chen, Min Lin, 2016, Organic letters.

Constituents from Polygonum cuspidatum.

D. Bai, L. Xuan, Ya-ming Xu, 2002, Chemical & pharmaceutical bulletin.

Using the heat-shock response to discover anticancer compounds that target protein homeostasis.

S. Lindquist, J. Clardy, S. Kesari, 2011, ACS chemical biology.

DNA damaging activity of ellagic acid derivatives.

S. Hecht, Ji Ma, S. H. Jones, 2003, Bioorganic & medicinal chemistry.

Influence of rhamnose substituents on the potency of SL0101, an inhibitor of the Ser/Thr kinase, RSK.

D. Lannigan, D. Maloney, S. Hecht, 2006, Bioorganic & medicinal chemistry.

Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation.

Timothy M. Errington, T. Errington, D. Lannigan, 2005, Cancer research.

Semi-synthesis and cytotoxicity evaluation of pyrimidine, thiazole, and indole analogues of argentatins A–C from guayule (Parthenium argentatum) resin

I. Molnár, E. Wijeratne, Chandrashekhar Madasu, 2021, Medicinal Chemistry Research.

Delitschiapyrone A, a Pyrone–Naphthalenone Adduct Bearing a New Pentacyclic Ring System from the Leaf-Associated Fungus Delitschia sp. FL1581

A. Arnold, J. U’Ren, A. Gunatilaka, 2014, Organic letters.

Characterization of the Biosynthetic Genes for 10,11-Dehydrocurvularin, a Heat Shock Response-Modulating Anticancer Fungal Polyketide from Aspergillus terreus

Wei Zhang, Min Lin, Yuquan Xu, 2013, Applied and Environmental Microbiology.

Strobiloscyphones A-F, 6-Isopentylsphaeropsidones and Other Metabolites from Strobiloscypha sp. AZ0266, a Leaf-Associated Fungus of Douglas Fir.

A. Arnold, J. U’Ren, Wei Qu, 2021, Journal of natural products.

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.

T. Sayers, A. Brooks, C. J. Henrich, 2017, Journal of medicinal chemistry.

Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model.

E. Wijeratne, M. Cuendet, M. Issa, 2021, Journal of natural products.

Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells.

T. Sayers, A. Brooks, P. Tewary, 2017, Journal of natural products.

Sesquiterpenes and other constituents of Xylaria sp. NC1214, a fungal endophyte of the moss Hypnum sp.

A. Arnold, J. U’Ren, A. Gunatilaka, 2015, Phytochemistry.

Withaferin A Analogs That Target the AAA+ Chaperone p97.

Donna D. Zhang, Tongde Wu, A. Gunatilaka, 2015, ACS chemical biology.

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

R. Chari, T. Sayers, A. Brooks, 2021, Cancer Research.

Physachenolide C is a Potent, Selective BET Inhibitor.

N. Horton, M. Clarkson, R. Fromme, 2022, Journal of medicinal chemistry.

Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesis

Xiaoyi Wei, I. Molnár, Shenglan Li, 2018, Proceedings of the National Academy of Sciences.

Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels.

Ann M. Thomas, M. Patek, R. Khanna, 2019, ACS chemical neuroscience.

Anti-HIV activities of the compounds isolated from Polygonum cuspidatum and Polygonum multiflorum.

Yong-tang Zheng, Liu-meng Yang, Yun-hua Wang, 2010, Planta medica.

Stilbene glycoside sulfates from Polygonum cuspidatum

D. Bai, L. Xuan, K. Xiao, 2000 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

2,3-Dihydrowithaferin A-3beta-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera.

L. Whitesell, S. P. Mclaughlin, A. Gunatilaka, 2009, Bioorganic & medicinal chemistry.

Discovery of diminazene as a dual inhibitor of SARS-CoV-2 human host proteases TMPRSS2 and furin using cell-based assays

Ya-ming Xu, M. C. Inácio, A. L. Gunatilaka, 2022, Current Research in Chemical Biology.

Preparation of monoclonal antibody against crocin and its characterization

Y. Shoyama, Hiroyuki Tanaka, Lijiang Xuan, 2004, Cytotechnology.

Anteaglonialides A-F and Palmarumycins CE(1)-CE(3) from Anteaglonium sp. FL0768, a Fungal Endophyte of the Spikemoss Selaginella arenicola.

A. Arnold, J. U’Ren, A. Gunatilaka, 2015, Journal of natural products.

Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica.

T. Sayers, A. Brooks, P. Tewary, 2018, Phytochemistry.

17β-Hydroxy-18-acetoxywithanolides from Aeroponically Grown Physalis crassifolia and Their Potent and Selective Cytotoxicity for Prostate Cancer Cells.

D. Bunting, A. Gunatilaka, Ya-ming Xu, 2016, Journal of natural products.

Structure-activity relationships for withanolides as inducers of the cellular heat-shock response.

S. Lindquist, S. Santagata, L. Whitesell, 2014, Journal of medicinal chemistry.

Cytotoxic Physalins from Aeroponically Grown Physalis acutifolia.

A. Gunatilaka, E. Wijeratne, F. Ranjbar, 2021, Journal of natural products.

Polybrominated diphenyl ethers from a sponge of the Dysidea genus that inhibit Tie2 kinase.

S. Hecht, Randall K. Johnson, Ya-ming Xu, 2005, Bioorganic & medicinal chemistry.

Secoemestrin D, a cytotoxic epitetrathiodioxopiperizine, and emericellenes A-E, five sesterterpenoids from Emericella sp. AST0036, a fungal endophyte of Astragalus lentiginosus1.

A. Arnold, A. Gunatilaka, Patricia Espinosa-Artiles, 2013, Journal of natural products.

Unusual withanolides from aeroponically grown Withania somnifera.

Song Gao, D. Bunting, A. Gunatilaka, 2011, Phytochemistry.

Three acetylated flavonol glycosides from Forsteronia refracta that specifically inhibit p90 RSK.

D. Lannigan, S. Hecht, Ya-ming Xu, 2006, Bioorganic & medicinal chemistry.

Cytotoxic Cytochalasins and Other Metabolites from Xylariaceae sp. FL0390, a Fungal Endophyte of Spanish Moss

A. Arnold, J. U’Ren, A. Gunatilaka, 2015, Natural product communications.

Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei.

F. Valeriote, A. Gunatilaka, Song Gao, 2011, Journal of natural products.

Montagnuphilones A-G, Azaphilones from Montagnulaceae sp. DM0194, a Fungal Endophyte of Submerged Roots of Persicaria amphibia.

A. Arnold, A. Gunatilaka, Jianguang Luo, 2017, Journal of natural products.

Sorbifolivaltrates A-D, diene valepotriates from Valeriana sorbifolia(1).

S. P. Mclaughlin, A. Gunatilaka, Ya-ming Xu, 2007, Journal of natural products.

Microbial transformation of some triterpenoids of Guayule resin by Chaetomium sp.

E. Wijeratne, Chandrashekhar Madasu, M. C. Inácio, 2023, Phytochemistry Letters.

Cycloartane- and Lanostane-Type Triterpenoids from the Resin of Parthenium argentatum AZ-2, a Byproduct of Guayule Rubber Production

D. Dierig, I. Molnár, E. Wijeratne, 2021, ACS omega.

Teratopyrones A–C, Dimeric Naphtho-γ-Pyrones and Other Metabolites from Teratosphaeria sp. AK1128, a Fungal Endophyte of Equisetum arvense

A. Arnold, A. Gunatilaka, Wen-qiong Wang, 2020, Molecules.

Cytotoxic and Noncytotoxic Metabolites from Teratosphaeria sp. FL2137, a Fungus Associated with Pinus clausa.

A. Arnold, J. U’Ren, A. Gunatilaka, 2018, Journal of natural products.

Dimeric stilbene glycosides from polygonum suspidatum

Naixia Zhang, Houming Wu, D. Bai, 2002 .

Discovery of Potent 17β-Hydroxywithanolides for Castration-Resistant Prostate Cancer by High-Throughput Screening of a Natural Products Library for Androgen-Induced Gene Expression Inhibitors.

G. Paine-Murrieta, S. Felder, A. Gunatilaka, 2015, Journal of medicinal chemistry.

An Analog of Withaferin A Activates the MAPK and Glutathione “Stress” Pathways and Inhibits Pancreatic Cancer Cell Proliferation

W. Qi, L. Cooke, D. Mahadevan, 2011, Cancer investigation.

Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma.

T. Sayers, A. Brooks, P. Tewary, 2021, Journal of natural products.

Argentatin C Analogues with Potential Antinociceptive Activity and Other Triterpenoid Constituents from the Aerial Parts of Parthenium incanum

E. Wijeratne, Aida Calderón-Rivera, S. Perez-Miller, 2023, ACS omega.

The natural product argentatin C attenuates postoperative pain via inhibition of voltage‐gated sodium and T‐type voltage‐gated calcium channels

J. Streicher, E. Wijeratne, G. Zamponi, 2022, British journal of pharmacology.

Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation.

L. Whitesell, A. Gunatilaka, E. Wijeratne, 2018, Journal of Natural Products.

2,3-Dihydrowithaferin A-3beta-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera.

L. Whitesell, S. P. Mclaughlin, A. Gunatilaka, 2009, Bioorganic & medicinal chemistry.

Production and Structural Diversification of Withanolides by Aeroponic Cultivation of Plants of Solanaceae: Cytotoxic and Other Withanolides from Aeroponically Grown Physalis coztomatl

Lijiang Xuan, E. Wijeratne, Wen-qiong Wang, 2022, Molecules.

Using the heat-shock response to discover anticancer compounds that target protein homeostasis.

S. Lindquist, J. Clardy, S. Kesari, 2011, ACS chemical biology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

Cytotoxic Terpenoid and Immunosuppressive Phenolic Glycosides from the Root Bark of Dictamnus dasycarpus

L. Xuan, Jun Chang, Ya-Ming Xu, 2002, Planta medica.

Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest

Alexandra E. Charos, M. Bosenberg, E. Wijeratne, 2021, bioRxiv.

Biosynthesis of Cytosporones in Leotiomycetous Filamentous Fungi.

Patricia Espinosa-Artiles, Hang Liu, Chen Wang, 2024, Journal of the American Chemical Society.