Jonathan L. Papa

Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA.

Mark J. Mitton-Fry, S. Lindert, C. McElroy, 2021, Journal of medicinal chemistry.

Dioxane-Linked Amide Derivatives as Novel Bacterial Topoisomerase Inhibitors against Gram-Positive Staphylococcus aureus.

S. Lindert, D. Wozniak, Justin T. Seffernick, 2020, ACS medicinal chemistry letters.

CRISPR/Cas9 Genome Editing of the Human Topoisomerase IIα Intron 19 5′ Splice Site Circumvents Etoposide Resistance in Human Leukemia K562 Cells

T. Elton, H. Ozer, Junan Li, 2021, Molecular Pharmacology.

hsa-miR-9-3p and hsa-miR-9-5p as Post-Transcriptional Modulators of DNA Topoisomerase IIα in Human Leukemia K562 Cells with Acquired Resistance to Etoposide

T. Elton, H. Ozer, J. Yalowich, 2019, Molecular Pharmacology.

Novel bacterial topoisomerase inhibitors derived from isomannide.

Mark J. Mitton-Fry, J. Gallucci, A. Okumu, 2020, European journal of medicinal chemistry.

1,3-Dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Expanding Structural Diversity and the Antibacterial Spectrum.

Mark J. Mitton-Fry, N. Osheroff, M. Hazbón, 2022, ACS medicinal chemistry letters.

Dioxane-Linked Amide Derivatives as Novel Bacterial Topoisomerase Inhibitors against Gram-Positive Staphylococcus aureus.

Mark J. Mitton-Fry, S. Lindert, D. Wozniak, 2020, ACS medicinal chemistry letters.

Innate immune control of influenza virus interspecies adaptation

R. Webby, A. Bowman, A. Kenney, 2023, bioRxiv.