H. Webb

发表

Amino acid/spermine conjugates: polyamine amides as potent spermidine uptake inhibitors.

G. F. Graminski, M. Burns, F. Cai, 2001, Journal of medicinal chemistry.

4-Chlorothreonine Is Substrate, Mechanistic Probe, and Mechanism-based Inactivator of Serine Hydroxymethyltransferase (*)

R. Matthews, H. Webb, 1995, The Journal of Biological Chemistry.

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital.

J. Lehmann, C. Afshari, H. Hamadeh, 2002, Molecular pharmacology.

Novel lysine-spermine conjugate inhibits polyamine transport and inhibits cell growth when given with DFMO.

M. Burns, F. Cai, S. Vanderwerf, 2000, Experimental cell research.

Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.

M. Weller, W. Wick, A. Protter, 2007, Neuro-oncology.

Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia.

R. Ulrich, J. Byrd, I. Flinn, 2014, Blood.

Pharmacological Properties of SD-282 – An α-Isoform Selective Inhibitor for p38 MAP Kinase

S. Medicherla, A. Protter, A. Kapoun, 2008, Pharmacology.

Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension.

D. Macintyre, Sampathkumar Anandan, D. Chen, 2011, European journal of pharmacology.

Idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase-δ, as therapy for previously treated indolent non-Hodgkin lymphoma.

Yoonjin Cho, John P Leonard, R. Ulrich, 2014, Blood.

1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: simple synthetic polyamine analogues that differentially alter tubulin polymerization.

P. Woster, R. Casero, Z. Wu, 1999, Journal of medicinal chemistry.

Epoxyeicosatrienoic Acids Prevent Cisplatin-Induced Renal Apoptosis through a p38 Mitogen-Activated Protein Kinase–Regulated Mitochondrial Pathway

D. Kroetz, J. Olson, H. K. Webb, 2013, Molecular Pharmacology.

Clinical Safety and Activity In a Phase 1 Study of CAL-101, An Isoform-Selective Inhibitor of Phosphatidylinositol 3-Kinase P110δ, In Patients with Relapsed or Refractory Non-Hodgkin Lymphoma

R. Ulrich, J. Byrd, I. Flinn, 2010 .

Clinical Pharmacokinetics of CAL-101, a p110δ Isoform-Selective PI3K Inhibitor, Following Single- and Multiple-Dose Administration In Healthy Volunteers and Patients with Hematological Malignancies

R. Ulrich, L. Miller, Hao Chen, 2010 .

Purification and characterization of the M.RsrI DNA methyltransferase from Escherichia coli.

R. Gumport, W. Kaszubska, H. K. Webb, 1992, Gene.

Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation and dyslipidemia in apolipoprotein E deficient mice infused with angiotensin II

D. Chen, Ying Cheng, Yi-xin Wang, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Cobalamin-dependent methionine synthase and serine hydroxymethyltransferase: targets for chemotherapeutic intervention?

R. Matthews, J. Drummond, H. K. Webb, 1998, Advances in enzyme regulation.

Pharmacokinetics and Pharmacodynamics of AR9281, an Inhibitor of Soluble Epoxide Hydrolase, in Single‐ and Multiple‐Dose Studies in Healthy Human Subjects

Sampathkumar Anandan, D. Patel, D. Chen, 2012, Journal of clinical pharmacology.

ATTENUATION OF CISPLATIN-INDUCED RENAL INJURY BY INHIBITION OF SOLUBLE EPOXIDE HYDROLASE INVOLVES NF-κB SIGNALING

S. Markova, D. Kroetz, Yingmei Liu, 2012 .

Attenuation of Cisplatin-Induced Renal Injury by Inhibition of Soluble Epoxide Hydrolase Involves Nuclear Factor κB Signaling

S. Markova, D. Kroetz, H. Fukushima, 2012, Journal of Pharmacology and Experimental Therapeutics.

1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.

Paul D. Jones, B. Hammock, D. Macintyre, 2011, Bioorganic & medicinal chemistry letters.

Unsymmetrical non-adamantyl N,N'-diaryl urea and amide inhibitors of soluble expoxide hydrolase.

Sampathkumar Anandan, R. Gless, Zung N. Do, 2009, Bioorganic & medicinal chemistry letters.

Non-urea functionality as the primary pharmacophore in soluble epoxide hydrolase inhibitors.

Sampathkumar Anandan, D. Patel, R. Gless, 2009, Bioorganic & medicinal chemistry letters.

The Combination of Entospletinib and Vincristine Demonstrates Synergistic Activity in a Broad Panel of Hematological Cancer Cell Lines and Anti-Tumor Efficacy in a DLBCL Xenograft Model

A. Clarke, J. Silverman, M. Axelrod, 2015 .