G. Smith

发表

The effects of 1-methyl-5-thiotetrazole in a rat liver vitamin K-dependent carboxylase assay.

G. F. Smith, J. Sundboom, G. Smith, 1984, Thrombosis research.

Structure-activity study of tripeptide thrombin inhibitors using alpha-alkyl amino acids and other conformationally constrained amino acid substitutions.

D. Gifford-Moore, J. Paschal, P. Gesellchen, 1995, Journal of medicinal chemistry.

Effect of LY287045, a thrombin/trypsin inhibitor, on thrombin and trypsin-induced aortic contraction and relaxation.

G. F. Smith, M. Cohen, A. Bhattacharya, 2001, The Journal of pharmacology and experimental therapeutics.

The design of potent, selective, non-covalent, peptide thrombin inhibitors utilizing imidazole as a S1 binding element.

A. Schacht, N. Chirgadze, S. Briggs, 1999, Bioorganic & medicinal chemistry letters.

Dibasic benzo[b]thiophene derivatives as a novel class of active site-directed thrombin inhibitors. 1. Determination of the serine protease selectivity, structure-activity relationships, and binding orientation.

R. W. Harper, N. Chirgadze, S. Briggs, 1997, Journal of medicinal chemistry.

Heparin and protease inhibition. I. Heparin complexes with thrombin, plasmin, and trypsin.

G. F. Smith, J. Sundboom, G. Smith, 1981, Thrombosis research.

Structure-based design of potent, amidine-derived inhibitors of factor Xa: evaluation of selectivity, anticoagulant activity, and antithrombotic activity.

J. A. Kyle, N. Chirgadze, S. Briggs, 2000, Journal of Medicinal Chemistry.

1,2-Dibenzamidobenzene inhibitors of human factor Xa.

J. A. Kyle, J. Wikel, B. Eastwood, 2000, Journal of medicinal chemistry.

Correlation of the in vivo anticoagulant, antithrombotic, and antimetastatic efficacy of warfarin in the rat.

J. D. Frank, B. Neubauer, R. Merriman, 1988, Thrombosis research.

Heparin and protease inhibition. II. The role of heparin in the ATIII inactivation of thrombin, plasmin, and trypsin.

G. F. Smith, J. Sundboom, G. Smith, 1981, Thrombosis research.

The heparin-thrombin complex in the mechanism of thrombin inactivation by heparin.

G. F. Smith, G. Smith, G. F. Smith, 1977, Biochemical and biophysical research communications.

Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity.

J. T. Metz, J. Masters, T. Craft, 2000, Journal of medicinal chemistry.

Dibasic benzo[B]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 4. SAR studies on the conformationally restricted C3-side chain of hydroxybenzo[B]thiophenes.

K. Takeuchi, J. Mccowan, D. Gifford-Moore, 1999, Bioorganic & medicinal chemistry letters.

Thrombolytic activity of a novel plasminogen activator, LY210825, compared with recombinant tissue-type plasminogen activator in a canine model of coronary artery thrombosis.

G. F. Smith, J. L. Bobbitt, T. Craft, 1990, Circulation.

Preliminary X-ray diffraction studies of recombinant 19 kDa human fibroblast collagenase.

R. Anderegg, M. Milburn, A. Hassell, 1994, Journal of molecular biology.