Seitaro Nomura

发表

Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL‐Induced Osteoclastogenesis

H. Aburatani, Y. Kadono, Sakae Tanaka, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Single-Cell Analysis Revealed the Role of CD8+ Effector T Cells in Preventing Cardioprotective Macrophage Differentiation in the Early Phase of Heart Failure

A. Yoshimura, S. Nomura, T. Ko, 2021, Frontiers in Immunology.

Single-cell genomics to understand disease pathogenesis

S. Nomura, Seitaro Nomura, 2020, Journal of human genetics.

Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

H. Aburatani, Y. Kamatani, K. Matsuda, 2020, Nature Genetics.

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

I. Komuro, I. Shiojima, S. Nomura, 2012, Cell.

CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data

Koji Tsuda, Hiroyuki Aburatani, David duVerle, 2016, BMC Bioinformatics.

Manipulating Cardiomyocyte Plasticity for Heart Regeneration

S. Nomura, T. Ko, Seitaro Nomura, 2022, Frontiers in Cell and Developmental Biology.

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

H. Aburatani, I. Komuro, S. Nomura, 2018, Nature Communications.

Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner

H. Aburatani, Tetsuhiro Tanaka, M. Nangaku, 2017, Scientific Reports.

Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis

H. Aburatani, Bo Zhang, M. Ikeuchi, 2022, Nature Communications.

Single-Cardiomyocyte RNA Sequencing to Dissect the Molecular Pathophysiology of the Heart.

H. Aburatani, I. Komuro, S. Nomura, 2021, Methods in molecular biology.

Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury

E. Susaki, H. Ueda, I. Komuro, 2021, Journal of the American Society of Nephrology : JASN.

Identification of MYLK3 mutations in familial dilated cardiomyopathy

H. Aburatani, N. Hagiwara, I. Komuro, 2017, Scientific Reports.

DNA single-strand break-induced DNA damage response causes heart failure

I. Komuro, I. Shiojima, S. Nomura, 2017, Nature Communications.

Promotion of CHIP-Mediated p53 Degradation Protects the Heart From Ischemic Injury

I. Komuro, I. Shiojima, S. Nomura, 2010, Circulation research.

Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling

T. Noda, I. Komuro, I. Shiojima, 2015, Nature Communications.

Activation of endothelial β-catenin signaling induces heart failure

T. Noda, I. Komuro, I. Shiojima, 2016, Scientific Reports.

Wnt/&bgr;-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box O

I. Komuro, I. Shiojima, S. Nomura, 2015, Circulation. Heart failure.

Precision medicine for heart failure based on molecular mechanisms The Research Achievement Award Lecture.

I. Komuro, S. Nomura, Seitaro Nomura, 2020, Journal of molecular and cellular cardiology.

Wnt Signaling in Cardiogenesis

I. Komuro, I. Shiojima, S. Nomura, 2013 .

Genetic and non-genetic determinants of clinical phenotypes in cardiomyopathy.

S. Nomura, Seitaro Nomura, 2019, Journal of cardiology.

Review of Single-Cell RNA Sequencing in the Heart

S. Nomura, Shintaro Yamada, S. Yamada, 2020, International journal of molecular sciences.

Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure

M. Hattori, K. Honda, H. Morita, 2017, PloS one.

Recent Findings Related to Cardiomyopathy and Genetics

S. Nomura, Takanobu Yamada, Seitaro Nomura, 2021, International Journal of Molecular Sciences.

Recent Progress in Cardiovascular Research Involving Single-Cell Omics Approaches

S. Nomura, Zhehao Dai, Seitaro Nomura, 2021, Frontiers in Cardiovascular Medicine.

Immunobiology Approach for Further Development of Precision Medicine in Heart Failure

S. Nomura, Seitaro Nomura, 2019 .

Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice.

I. Komuro, S. Nomura, Y. Kubota, 2021, Circulation.

High-throughput single-molecule RNA imaging analysis reveals heterogeneous responses of cardiomyocytes to hemodynamic overload.

H. Aburatani, I. Komuro, S. Nomura, 2019, Journal of molecular and cellular cardiology.

MR imaging of normal perivascular space expansion at midbrain.

Motoki Sato, S. Nomura, A. Yamaura, 2005, AJNR. American journal of neuroradiology.

Distinct variants affecting differential splicing of TGFBR1 exon 5 cause either Loeys–Dietz syndrome or multiple self-healing squamous epithelioma

I. Komuro, S. Nomura, E. Takimoto, 2018, European Journal of Human Genetics.

Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction

H. Aburatani, Y. Kamatani, K. Matsuda, 2023, Nature Genetics.

Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytes.

Y. Hata, I. Komuro, S. Nomura, 2019, Journal of molecular and cellular cardiology.

Hypoxia-Inducible Factor-1α Activates the Transforming Growth Factor-β/SMAD3 Pathway in Kidney Tubular Epithelial Cells

H. Aburatani, M. Nangaku, S. Nomura, 2016, American Journal of Nephrology.

Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure.

I. Komuro, S. Nomura, Toshihiro Yamaguchi, 2022, Biochemical and biophysical research communications.

Trans-ancestry genome-wide analysis of atrial fibrillation provides new insights into disease biology and enables polygenic prediction of cardioembolic risk

H. Aburatani, Y. Kamatani, K. Matsuda, 2021, medRxiv.

Population-specific and transethnic genome-wide analyses reveal distinct and shared genetic risks of coronary artery disease

H. Aburatani, Y. Kamatani, K. Matsuda, 2019, bioRxiv.

Cardiomyopathy with LMNA Mutation.

S. Nomura, Masamichi Ito, Seitaro Nomura, 2018, International heart journal.

Dilated cardiomyopathy with centronuclear myopathy in a young male.

I. Komuro, S. Nomura, N. Funabashi, 2011, International journal of cardiology.

Functional Evaluation of Human Bioengineered Cardiac Tissue Using iPS Cells Derived from a Patient with Lamin Variant Dilated Cardiomyopathy.

H. Aburatani, N. Hagiwara, Tatsuya Shimizu, 2022, International heart journal.

Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure

I. Komuro, K. Yoshimi, S. Nomura, 2020, Nature Communications.

Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury

H. Aburatani, Y. Hata, I. Komuro, 2018, JACC. Basic to translational science.

Cardiac neural crest lineage diversity and underlying gene regulatory networks revealed by multimodal analysis

H. Aburatani, S. Fukuda, S. Nomura, 2022, bioRxiv.

Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling

H. Aburatani, N. Hagiwara, I. Komuro, 2018, Scientific Reports.

Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling

H. Aburatani, N. Hagiwara, I. Komuro, 2018, Scientific Reports.

TEAD1 trapping by the Q353R–Lamin A/C causes dilated cardiomyopathy

H. Aburatani, Bo Zhang, M. Ikeuchi, 2023, Science advances.

Precision and genomic medicine for dilated and hypertrophic cardiomyopathy

S. Nomura, Seitaro Nomura, M. Ono, 2023, Frontiers in Cardiovascular Medicine.

Transethnic meta-analysis of genome-wide association studies identifies three new loci and characterizes population-specific differences for coronary artery disease

Y. Kamatani, K. Matsuda, K. Ozaki, 2019, bioRxiv.

Cardiac sarcoidosis evaluated by multimodality imaging.

I. Komuro, S. Nomura, N. Funabashi, 2011, International journal of cardiology.

Prediction of single-cell mechanisms for disease progression in hypertrophic remodelling by a trans-omics approach

Yoshihiro Yamanishi, I. Komuro, S. Nomura, 2021, Scientific Reports.

Phenotypic Screening Using Patient-Derived Induced Pluripotent Stem Cells Identified Pyr3 as a Candidate Compound for the Treatment of Infantile Hypertrophic Cardiomyopathy.

I. Komuro, I. Shiojima, S. Nomura, 2018, International heart journal.

Wnt Signaling in Cardiogenesis : Atsuhiko T. Naito, Seitaro Nomura, Ichiro Shiojima and Issei Komuro*

I. Shiojima, S. Nomura, A. Naito, 2013 .

Novel AGL variants in a patient with glycogen storage disease type IIIb and pulmonary hypertension caused by pulmonary veno-occlusive disease: A case report

H. Akazawa, M. Hatano, S. Minatsuki, 2023, Frontiers in Genetics.

Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling

S. Nomura, T. Yamauchi, H. Waki, 2022, Nature Communications.

Medical Interview Skills and Patient Satisfaction Levels in a Setting Utilizing Electronic Medical Records

S. Nomura, Y. Tokuda, Junko Takei, 2010 .

CXCR7 ameliorates myocardial infarction as a β-arrestin-biased receptor

I. Komuro, K. Otsu, S. Nomura, 2021, Scientific reports.

Identification of MYLK3 mutations in familial dilated cardiomyopathy

H. Aburatani, N. Hagiwara, I. Komuro, 2017, Scientific Reports.

Distinct variants affecting differential splicing of TGFBR1 exon 5 cause either Loeys–Dietz syndrome or multiple self-healing squamous epithelioma

I. Komuro, S. Nomura, E. Takimoto, 2018, European Journal of Human Genetics.

Spatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction

H. Aburatani, Bo Zhang, S. Nomura, 2022, Nature Cardiovascular Research.

Spatiotemporal single-cell analysis reveals critical roles of mechano-sensing genes at the border zone in remodeling after myocardial infarction

H. Aburatani, I. Komuro, S. Nomura, 2021 .

CXCR7 ameliorates myocardial infarction as a β-arrestin-biased receptor

K. Otsu, S. Nomura, M. Satoh, 2021, Scientific Reports.

Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1

H. Aburatani, Sakae Tanaka, S. Nomura, 2017, PloS one.

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

I. Komuro, I. Shiojima, T. Minamino, 2012, Cell.

Quantitative Measurement of GPCR Endocytosis via Pulse-Chase Covalent Labeling

I. Komuro, Kazuhiko Yamamoto, S. Nomura, 2015, PloS one.

Trends and Limitations in the Assessment of the Contractile Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes From Patients With Dilated Cardiomyopathy

I. Komuro, S. Nomura, H. Morita, 2020, Frontiers in Cardiovascular Medicine.

Monitoring β-arrestin recruitment via β-lactamase enzyme fragment complementation: purification of peptide E as a low-affinity ligand for mammalian bombesin receptors

I. Komuro, S. Nomura, M. Yanagisawa, 2015, PloS one.

LMNA Mutations and Right Heart Failure in Cardiomyopathy Patients With Left Ventricular Assist Devices.

H. Aburatani, S. Fukuda, M. Ono, 2023, Journal of cardiac failure.