K. Yoshida

发表

PKCδ signaling: Mechanisms of DNA damage response and apoptosis

K. Yoshida, 2007 .

An efficient system for secretory production of fibrinogen using a hepatocellular carcinoma cell line

T. Iwamoto, Kiyotsugu Yoshida, Katsuhiko Aoki, 2015, Hepatology research : the official journal of the Japan Society of Hepatology.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

DYRK2 regulates epithelial-mesenchymal-transition and chemosensitivity through Snail degradation in ovarian serous adenocarcinoma

N. Yanaihara, A. Okamoto, R. Mimoto, 2015, Tumor Biology.

Translocation of SAPK/JNK to Mitochondria and Interaction with Bcl-xL in Response to DNA Damage*

Zhi-Min Yuan, D. Kufe, P. Pandey, 2000, The Journal of Biological Chemistry.

Functional Interaction between SHPTP1 and the Lyn Tyrosine Kinase in the Apoptotic Response to DNA Damage*

D. Kufe, S. Kharbanda, D Kufe, 1999, The Journal of Biological Chemistry.

Proteasome inhibitor-resistant cells cause EMT-induction via suppression of E-cadherin by miR-200 and ZEB1.

K. Ohkawa, N. Yamaguchi, T. Asakura, 2015, International journal of oncology.

Crosstalk between tumor suppressors p53 and PKCδ: Execution of the intrinsic apoptotic pathways.

Kiyotsugu Yoshida, N. Dashzeveg, K. Yoshida, 2016, Cancer letters.

Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage

Yoshio Miki, Y. Miki, Kiyotsugu Yoshida, 2004, Cancer science.

ATM Augments Nuclear Stabilization of DYRK2 by Inhibiting MDM2 in the Apoptotic Response to DNA Damage*

Y. Miki, N. Taira, Tomoko Yamaguchi, 2009, The Journal of Biological Chemistry.

Downregulation of CD24 suppresses bone metastasis of lung cancer

M. Saito, Katsuhiko Aoki, K. Marumo, 2017, Cancer science.

Proteolytic Cleavage and Activation of Protein Kinase C μ by Caspase-3 in the Apoptotic Response of Cells to 1-β-d-Arabinofuranosylcytosine and Other Genotoxic Agents*

D. Kufe, Kiyotsugu Yoshida, R. Datta, 2000, The Journal of Biological Chemistry.

Caspase-3-mediated Cleavage of Protein Kinase C θ in Induction of Apoptosis*

D. Kufe, R. Datta, H. Kojima, 1997, The Journal of Biological Chemistry.

Role for Caspase-Mediated Cleavage of Rad51 in Induction of Apoptosis by DNA Damage

Zhi-Min Yuan, D. Kufe, Kiyotsugu Yoshida, 1999, Molecular and Cellular Biology.

Mechanical insights into the regulation of programmed cell death by p53 via mitochondria.

Kohji Yamada, Kiyotsugu Yoshida, K. Yoshida, 2019, Biochimica et biophysica acta. Molecular cell research.

Activation of SAPK/JNK Signaling by Protein Kinase Cδ in Response to DNA Damage*

Y. Miki, D. Kufe, Kiyotsugu Yoshida, 2002, The Journal of Biological Chemistry.

Role for Lyn Tyrosine Kinase as a Regulator of Stress-Activated Protein Kinase Activity in Response to DNA Damage

D. Kufe, Kiyotsugu Yoshida, S. Kharbanda, 2000, Molecular and Cellular Biology.

Functional Role for Protein Kinase Cβ as a Regulator of Stress-Activated Protein Kinase Activation and Monocytic Differentiation of Myeloid Leukemia Cells

D. Kufe, R. Stone, P. Pandey, 1999, Molecular and Cellular Biology.

Novel BRCA2‐interacting protein BJ‐HCC‐20A inhibits the induction of apoptosis in response to DNA damage

Y. Miki, A. Nakanishi, Go Tomiyoshi, 2008, Cancer science.

Tumor suppressor p53 induces miR‐1915 processing to inhibit Bcl‐2 in the apoptotic response to DNA damage

Kiyotsugu Yoshida, N. Dashzeveg, Kazuya Nakazawa, 2014, The FEBS journal.

DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells.

Y. Miki, N. Taira, R. Mimoto, 2012, The Journal of clinical investigation.

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.

Y. Miki, N. Taira, Tomoko Yamaguchi, 2007, Molecular cell.

Protein Kinase C Delta Is a Novel Biomarker for Hepatocellular Carcinoma

M. Saruta, Kiyotsugu Yoshida, Tsunekazu Oikawa, 2022, Gastro hep advances.

Protein kinase Cδ is responsible for constitutive and DNA damage‐induced phosphorylation of Rad9

Y. Miki, D. Kufe, Kiyotsugu Yoshida, 2003, The EMBO journal.

Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient

S. Toyokuni, Kiyotsugu Yoshida, T. Horii, 2021, Communications biology.

Forced expression of DYRK2 exerts anti-tumor effects via apoptotic induction in liver cancer.

M. Saruta, Kiyotsugu Yoshida, S. Hirooka, 2019, Cancer letters.

Tumor suppressive role for kinases phosphorylating p53 in DNA damage‐induced apoptosis

Kiyotsugu Yoshida, S. Yogosawa, K. Yoshida, 2018, Cancer science.

Downregulation of dual‐specificity tyrosine‐regulated kinase 2 promotes tumor cell proliferation and invasion by enhancing cyclin‐dependent kinase 14 expression in breast cancer

Kiyotsugu Yoshida, T. Morikawa, R. Mimoto, 2018, Cancer science.

Biological Consequences of Priming Phosphorylation in Cancer Development

Katsuhiko Aoki, K. Yoshida, 2017 .

Dual‐specificity tyrosine‐regulated kinase 2 is a suppressor and potential prognostic marker for liver metastasis of colorectal cancer

R. Mimoto, S. Hirooka, K. Yanaga, 2017, Cancer science.

Interaction between RNF8 and DYRK2 is required for the recruitment of DNA repair molecules to DNA double‐strand breaks

Kiyotsugu Yoshida, T. Sawasaki, Katsuhiko Aoki, 2017, FEBS letters.

Diminished DYRK2 sensitizes hormone receptor-positive breast cancer to everolimus by the escape from degrading mTOR.

Kiyotsugu Yoshida, R. Mimoto, N. T. Nihira, 2017, Cancer letters.

MUC 1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage

D. Kufe, Kiyotsugu Yoshida, S. Kharbanda, 2013 .

MUC1 oncoprotein blocks nuclear targeting of c‐Abl in the apoptotic response to DNA damage

D. Kufe, Kiyotsugu Yoshida, S. Kharbanda, 2006, The EMBO journal.

PKCδ regulates Mdm2 independently of p53 in the apoptotic response to DNA damage

Y. Miki, Kiyotsugu Yoshida, Hanshao Liu, 2011, Molecular carcinogenesis.

Identification of dihydropyrimidinase‐related protein 4 as a novel target of the p53 tumor suppressor in the apoptotic response to DNA damage

Y. Miki, J. Kimura, K. Yoshida, 2011, International journal of cancer.

DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter.

Y. Miki, Tomoko Yamaguchi, Hanshao Liu, 2009, The Biochemical journal.

Lyn Tyrosine Kinase Inhibits Nuclear Export of the p53 Tumor Suppressor

R. Weichselbaum, D. Kufe, Kiyotsugu Yoshida, 2002, Cancer biology & therapy.

A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress

Yoshio Miki, Y. Miki, N. Taira, 2008, Nucleic acids research.

The c-Abl tyrosine kinase stabilizes Pitx1 in the apoptotic response to DNA damage

Y. Miki, Kiyotsugu Yoshida, Tomoko Yamaguchi, 2010, Apoptosis.

JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage

Tohru Natsume, Yoshio Miki, Y. Miki, 2005, Nature Cell Biology.

c-Abl Tyrosine Kinase Regulates the Human Rad9 Checkpoint Protein in Response to DNA Damage

D. Kufe, Kiyotsugu Yoshida, Hong-Gang Wang, 2002, Molecular and Cellular Biology.

Enforced dual‐specificity tyrosine‐regulated kinase 2 expression by adenovirus‐mediated gene transfer inhibits tumor growth and metastasis of colorectal cancer

Kiyotsugu Yoshida, S. Yoshida, K. Eto, 2021, Cancer science.

Binding of IgG-Opsonized Particles to FcγR Is an Active Stage of Phagocytosis That Involves Receptor Clustering and Phosphorylation1

K. Kwiatkowska, A. Sobota, Katarzyna Kwiatkowska, 2005, The Journal of Immunology.

Unconventional Secretion of PKCδ Exerts Tumorigenic Function via Stimulation of ERK1/2 Signaling in Liver Cancer

M. Saruta, Kohji Yamada, Kiyotsugu Yoshida, 2020, Cancer Research.

Cell death decision by p53 via control of the mitochondrial membrane.

Kiyotsugu Yoshida, N. Dashzeveg, K. Yoshida, 2015, Cancer letters.

Programmed cell death 6, a novel p53‐responsive gene, targets to the nucleus in the apoptotic response to DNA damage

Y. Miki, N. Taira, N. Dashzeveg, 2012, Cancer science.

D4S234E, a novel p53-responsive gene, induces apoptosis in response to DNA damage.

Yoshio Miki, Y. Miki, J. Kimura, 2010, Experimental cell research.

DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail.

Y. Miki, N. Taira, Hiroyuki Takahashi, 2013, Cancer letters.

Multiple functions of DYRK2 in cancer and tissue development

S. Yoshida, K. Yoshida, 2019, FEBS letters.

Engagement of DYRK2 in proper control for cell division

Kiyotsugu Yoshida, N. T. Nihira, K. Yoshida, 2015, Cell cycle.

Role for DYRK family kinases on regulation of apoptosis.

K. Yoshida, 2008, Biochemical pharmacology.

Protein Kinase C δ Regulates Ser46 Phosphorylation of p53 Tumor Suppressor in the Apoptotic Response to DNA Damage*

Yoshio Miki, Y. Miki, Hanshao Liu, 2006, Journal of Biological Chemistry.

The functional role for condensin in the regulation of chromosomal organization during the cell cycle

Kiyotsugu Yoshida, Y. Kagami, K. Yoshida, 2016, Cellular and Molecular Life Sciences.

The cell death machinery governed by the p53 tumor suppressor in response to DNA damage

Y. Miki, K. Yoshida, 2010 .

Induction of amphiregulin by p53 promotes apoptosis via control of microRNA biogenesis in response to DNA damage

N. Taira, S. Higashiyama, Tomoko Yamaguchi, 2013, Proceedings of the National Academy of Sciences.

DF3/MUC1 Signaling In Multiple Myeloma Cells Is Regulated by Interleukin-7

D. Kufe, Jian Ren, Wei-hsuan Yu, 2003, Cancer biology & therapy.

Role for PKCδ on Apoptosis in the DNA Damage Response

K. Yoshida, 2011 .

Protein Kinase C, p53, and DNA Damage

K. Yoshida, 2010 .

Inhibition of Human p53 Basal Transcription by Down-regulation of Protein Kinase Cδ*

J. Bargonetti, T. Abbas, D. A. Foster, 2004, Journal of Biological Chemistry.

The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis

Kohji Yamada, Kiyotsugu Yoshida, K. Fujiwara, 2020, eLife.

Nuclear trafficking of pro-apoptotic kinases in response to DNA damage.

K. Yoshida, 2008, Trends in molecular medicine.

PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice

K. Sakimura, S. Shioda, Y. Iguchi, 2021, PloS one.

Protein kinase C δ activates IκB-kinase α to induce the p53 tumor suppressor in response to oxidative stress

Y. Miki, Kiyotsugu Yoshida, Tomoko Yamaguchi, 2007 .

Protein kinase Cdelta activates RelA/p65 and nuclear factor-kappaB signaling in response to tumor necrosis factor-alpha.

Y. Miki, Tomoko Yamaguchi, Hanshao Liu, 2009, Cancer research.

Protein Kinase C D Activates RelA/p65 and Nuclear Factor- K B Signaling in Response to Tumor Necrosis Factor- A

Y. Miki, Kiyotsugu Yoshida, Tomoko Yamaguchi, 2009 .

Protein Kinase C δ Activates Topoisomerase IIα To Induce Apoptotic Cell Death in Response to DNA Damage

Y. Miki, K. Nakayama, N. Taira, 2006, Molecular and Cellular Biology.

BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress.

Y. Miki, H. Shinagawa, K. Yoshida, 2008, Antioxidants & redox signaling.

Negative Regulation of the SHPTP 1 Protein Tyrosine Phosphatase by Protein Kinase C in Response to DNA Damage

D. Kufe, K. Yoshida, 2001 .

Identification of Evi-1 as a novel effector of PKCδ in the apoptotic response to DNA damage.

Y. Miki, Kiyotsugu Yoshida, J. Kimura, 2011, Biochimica et biophysica acta.

Multiple subcellular localizations and functions of protein kinase Cδ in liver cancer

Kohji Yamada, K. Yoshida, 2022, World journal of gastroenterology.

Plk1 phosphorylation of CAP-H2 triggers chromosome condensation by condensin II at the early phase of mitosis

M. Ono, Y. Kagami, K. Yoshida, 2017, Scientific Reports.

Protein Kinase C (cid:2) Induces Transcription of the TP53 Tumor Suppressor Gene by Controlling Death-Promoting Factor Btf in the Apoptotic Response to DNA Damage (cid:1)

Y. Miki, Hanshao Liu, Zheng-Guang Lu, 2007 .

Functional Interaction between SHPTP 1 and the Lyn Tyrosine Kinase in the Apoptotic Response to DNA Damage *

D. Kufe, S. Kharbanda, K. Yoshida, 1999 .

PKC and apoptotic cell death upon genotoxic insults

K. Yoshida, 2017 .

TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress

Y. Miki, N. Taira, Kiyotsugu Yoshida, 2008, Oncogene.

Regulation for nuclear targeting of the Abl tyrosine kinase in response to DNA damage.

Kiyotsugu Yoshida, K. Yoshida, 2007, Advances in experimental medicine and biology.

Enabling Death by the Abl Tyrosine Kinase: Mechanisms for Nuclear Shuttling of c-Abl in Response to DNA Damage

Y. Miki, Kiyotsugu Yoshida, K. Yoshida, 2005, Cell cycle.

PKCdelta signaling: mechanisms of DNA damage response and apoptosis.

K. Yoshida, 2007, Cellular signalling.

Transcriptional induction of protein kinase C delta by p53 tumor suppressor in the apoptotic response to DNA damage.

N. Dashzeveg, S. Yogosawa, K. Yoshida, 2016, Cancer letters.

The Deubiquitinating Enzyme USP11 Controls an IκB Kinase α (IKKα)-p53 Signaling Pathway in Response to Tumor Necrosis Factor α (TNFα)*

Y. Miki, Kiyotsugu Yoshida, Tomoko Yamaguchi, 2007, Journal of Biological Chemistry.

Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage.

Y. Miki, Kiyotsugu Yoshida, Hanshao Liu, 2007, Molecular and cellular biology.

Quantification of the CD55 and CD59, Membrane Inhibitors of Complement on HIV‐1 Particles as a Function of Complement‐Mediated Virolysis

Kiyotsugu Yoshida, H. Okada, H. Sasaki, 1996, Microbiology and immunology.

Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage.

Yoshio Miki, Y. Miki, Hanshao Liu, 2006, The Journal of biological chemistry.

Carbonic anhydrase 13 suppresses bone metastasis in breast cancer.

A. Ryo, J. Nakayama, M. Nishi, 2021, Cancer treatment and research communications.

Regulation of a Transient Receptor Potential (TRP) Channel by Tyrosine Phosphorylation

Kiyotsugu Yoshida, D. Cohen, Hongyu Zhao, 2003, The Journal of Biological Chemistry.

Clinical implications of drug-screening assay for recurrent metastatic hormone receptor-positive, human epidermal receptor 2-negative breast cancer using conditionally reprogrammed cells

Kiyotsugu Yoshida, R. Mimoto, H. Takeyama, 2019, Scientific Reports.

Extracellular PKCδ signals to epidermal growth factor receptor for tumor proliferation in liver cancer cells

Kohji Yamada, Kiyotsugu Yoshida, Tsunekazu Oikawa, 2022, Cancer science.

A Novel Near-infrared Fluorescent Protein, iRFP720, Facilitates Transcriptional Profiling of Prostate Cancer Bone Metastasis in Mice.

Hiroyuki Takahashi, S. Egawa, Y. Kamata, 2017, Anticancer research.

Impairment of DYRK2 by DNMT1‑mediated transcription augments carcinogenesis in human colorectal cancer.

Kohji Yamada, S. Hirooka, S. Yoshida, 2020, International journal of oncology.

Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage.

Y. Miki, D. Kufe, Kiyotsugu Yoshida, 2002, The Journal of biological chemistry.

The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha).

Y. Miki, Kiyotsugu Yoshida, Tomoko Yamaguchi, 2007, The Journal of biological chemistry.

Mechanism of Inhibitory Effect of NCC164 on Replication of Human Immunodeficiency Virus

M. Nakamura, T. Ohno, K. Matsuzaki, 2001, Microbiology and immunology.

The cell death machinery governed by the p53 tumor suppressor in response to DNA damage.

Y. Miki, K. Yoshida, 2010, Cancer science.

Extended-synaptotagmin 1 engages in unconventional protein secretion mediated via SEC22B+ vesicle pathway in liver cancer

Kohji Yamada, Kiyotsugu Yoshida, M. Oka, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.

R. Weichselbaum, Zhi-Min Yuan, D. Kufe, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Plk1 phosphorylation of CAP-H2 triggers chromosome condensation by condensin II at the early phase of mitosis

M. Ono, Y. Kagami, K. Yoshida, 2017, Scientific Reports.

Impairment of DYRK2 augments stem-like traits by promoting KLF4 expression in breast cancer

R. Mimoto, S. Hirooka, H. Takeyama, 2017, Oncogene.

Inhibition of protein kinase C delta leads to cellular senescence to induce anti‐tumor effects in colorectal cancer

Kohji Yamada, S. Yoshida, Tomotaka Kumamoto, 2023, Cancer science.

Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells

D. Kufe, K. Yoshida, Y. Ito, 2001, Cell Death and Differentiation.

Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis

M. Ono, Y. Kagami, Shota Wada, 2014, The Journal of cell biology.

Proteasome inhibitor-resistant cells cause EMT-induction via suppression of E-cadherin by miR-200 and ZEB1.

K. Ohkawa, N. Yamaguchi, T. Asakura, 2015, International journal of oncology.

Cell death decision by p53 via control of the mitochondrial membrane.

N. Dashzeveg, K. Yoshida, Nurmaa K Dashzeveg, 2015, Cancer letters.

Novel BRCA2‐interacting protein BJ‐HCC‐20A inhibits the induction of apoptosis in response to DNA damage

Y. Miki, A. Nakanishi, Go Tomiyoshi, 2008, Cancer science.

Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage.

Y. Miki, K. Nakayama, N. Taira, 2006, Molecular and cellular biology.

Bio-artificial bone formation model with a radial-flow bioreactor for implant therapy—comparison between two cell culture carriers: porous hydroxyapatite and β-tricalcium phosphate beads

Kiyotsugu Yoshida, T. Matsuura, T. Masaki, 2018, Human Cell.