D. Clayton

D. Dairaghi, M. Schmitt, Mark E. Schmitt, 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Initiation and beyond: multiple functions of the human mitochondrial transcription machinery.

D. A. Clayton, Nicholas D Bonawitz, G. Shadel, 2006, Molecular cell.

Subtle determinants of the nucleocytoplasmic partitioning of in vivo-transcribed RNase MRP RNA in Xenopus laevis oocytes.

S. Jeong-Yu, A. Davis, D. Clayton, 1996, Gene expression.

A nuclear function for RNase MRP.

D. Clayton, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of a Xenopus laevis ribonucleoprotein endoribonuclease. Isolation of the RNA component and its expression during development.

S. Jeong-Yu, J. L. Bennett, D. Clayton, 1992, The Journal of biological chemistry.

Secondary structure of the RNA component of a nuclear/mitochondrial ribonucleoprotein.

J. N. Topper, D. Clayton, 1990, The Journal of biological chemistry.

Sequence and properties of the human KB cell and mouse L cell D-loop regions of mitochondrial DNA.

M. Walberg, D. Clayton, David A. Clayton, 1981, Nucleic acids research.

Elongation of displacement-loop strands in human and mouse mitochondrial DNA is arrested near specific template sequences.

D. A. Clayton, C. T. Wright, J. N. Doda, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Circular Dimer and Catenate Forms of Mitochondrial DNA in Human Leukaemic Leucocytes

D. A. Clayton, J. Vinograd, D. Clayton, 1967, Nature.

A transcription factor required for promoter recognition by human mitochondrial RNA polymerase. Accurate initiation at the heavy- and light-strand promoters dissected and reconstituted in vitro.

R. Fisher, D. Clayton, 1985, The Journal of biological chemistry.

Isolation of mammalian mitochondrial DNA and RNA and cloning of the mitochondrial genome.

R. V. van Etten, R. A. Etten, D. Tapper, 1983, Methods in enzymology.

Mechanism of mitochondrial DNA replication in mouse L-cells: RNA priming during the initiation of heavy-strand synthesis.

A. Gillum, D. Clayton, 1979, Journal of molecular biology.

Bovine RNase MRP cleaves the divergent bovine mitochondrial RNA sequence at the displacement-loop region

D. Dairaghi, D. Clayton, 1993, Journal of Molecular Evolution.

Conserved features of yeast and mammalian mitochondrial DNA replication.

M. Schmitt, D. Clayton, 1993, Current opinion in genetics & development.

DNA primase of human mitochondria is associated with structural RNA that is essential for enzymatic activity

T. Wong, D. Clayton, 1986, Cell.

In vitro replication of human mitochondrial DNA: Accurate initiation at the origin of light-strand synthesis

T. Wong, D. Clayton, 1985, Cell.

Priming of human mitochondrial DNA replication occurs at the light-strand promoter.

D. Chang, D. Clayton, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Nuclear gene products that function in mitochondrial DNA replication.

D. Clayton, 1987, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Template-directed pausing in in vitro DNA synthesis by DNA polymerase a from Drosophila melanogaster embryos.

D. A. Clayton, L. Kaguni, D. Clayton, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements

J. N. Topper, R. Fisher, D. Clayton, 1987, Cell.

Precise assignment of the light-strand promoter of mouse mitochondrial DNA: a functional promoter consists of multiple upstream domains

D. A. Clayton, D. Chang, D. Clayton, 1986, Molecular and cellular biology.

Precise assignment of the heavy-strand promoter of mouse mitochondrial DNA: cognate start sites are not required for transcriptional initiation

D. A. Clayton, D. Chang, D. Clayton, 1986, Molecular and cellular biology.

Hypoxic coordinate regulation of mitochondrial enzymes in mammalian cells.

D. A. Clayton, E. Robin, R. Wong, 1984, Science.

Nuclear gadgets in mitochondrial DNA replication and transcription.

D. Clayton, 1991, Trends in biochemical sciences.

Both the conserved stem-loop and divergent 5'-flanking sequences are required for initiation at the human mitochondrial origin of light-strand DNA replication.

J. Hixson, T. Wong, D. Clayton, 1986, The Journal of biological chemistry.

Nuclear‐mitochondrial intergenomic communication

D. Clayton, 1998, BioFactors.

Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator.

D. A. Clayton, G. Shadel, D. Dairaghi, 1995, Journal of molecular biology.

Recombination of Human Mitochondrial DNA

Konstantin Khrapko, K. Khrapko, M. Schwartz, 2004, Science.

Superresolution Fluorescence Imaging of Mitochondrial Nucleoids Reveals Their Spatial Range, Limits, and Membrane Interaction

Harald F Hess, Ariana N Tkachuk, H. Hess, 2011, Molecular and Cellular Biology.

Mechanism of replication of human mitochondrial DNA. Localization of the 5' ends of nascent daughter strands.

D. A. Clayton, D. Tapper, D. Clayton, 1981, The Journal of biological chemistry.

Backfoot is a novel homeobox gene expressed in the mesenchyme of developing hind limb

D. Clayton, Jin Shang, Ying Luo, 1997, Developmental dynamics : an official publication of the American Association of Anatomists.

Backfoot, a novel homeobox gene, maps to human chromosome 5 (BFT) and mouse chromosome 13 (Bft).

U. Francke, H. Ring, X. Li, 1997, Genomics.

The mitochondrial DNA replication bubble has not burst.

D. Bogenhagen, D. Clayton, 2003, Trends in biochemical sciences.

Genesis and Wanderings: Origins and Migrations in Asymmetrically Replicating Mitochondrial DNA

D. A. Clayton, T. Brown, D. Clayton, 2006, Cell cycle.

Transcription and replication of mitochondrial DNA.

D. Clayton, 2000, Human reproduction.

39 Mitochondrial DNA Replication

D. Clayton, 1996 .

Mechanism of mitochondrial DNA replication in mouse L-cells: localization and sequence of the light-strand origin of replication.

D. Clayton, P. A. Martens, 1979, Journal of molecular biology.

Mitochondrial DNA Replication: What We Know

D. Clayton, 2003, IUBMB life.

Correlative 3D superresolution fluorescence and electron microscopy reveal the relationship of mitochondrial nucleoids to membranes

Harald F Hess, D. A. Clayton, H. Hess, 2012, Proceedings of the National Academy of Sciences.

Native R-loops Persist throughout the Mouse Mitochondrial DNA Genome

T. Brown, A. N. Tkachuk, D. Clayton, 2008, Journal of Biological Chemistry.

Mitochondrial DNA of chloramphenicol-resistant mouse cells contains a single nucleotide change in the region encoding the 3' end of the large ribosomal RNA.

D. A. Clayton, D. Wallace, H. Blanc, 1981, Proceedings of the National Academy of Sciences of the United States of America.

The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria.

D. A. Clayton, E. Friedberg, J. N. Doda, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Detection of circular DNA from mitochondria of Neurospora crassa.

R. Brambl, D. Clayton, 1972, Biochemical and biophysical research communications.

Mechanism of mitochondrial DNA replication in mouse L-cells: asynchronous replication of strands, segregation of circular daughter molecules, aspects of topology and turnover of an initiation sequence.

A. J. Berk, D. Clayton, D. A. Clayton, 1974, Journal of molecular biology.

Dark‐field electron microscopy of unstained and unshadowed DNA *

R. Lemons, G. Haydon, D. Clayton, 1971, Journal of microscopy.

Differences in nuclear gene expression between cells containing monomer and dimer mitochondrial genomes.

L. Papadopoulou, T. Brown, M. Davidson, 2002, Gene.

Mitochondrial DNA of Human–Mouse Cell Hybrids

D. A. Clayton, W. Bodmer, R. Teplitz, 1971, Nature.

Studies of mouse mitochondrial DNA in escherichia coli: Structure and function of the eucaryotic-procaryotic chimeric plasmids

Stanley N Cohen, A. C. Chang, R. Lansman, 1975, Cell.

Occurrence of Complex Mitochondrial DNA in Normal Tissues

J. Vinograd, J. Jordan, D. Clayton, 1968, Nature.

Mitochondrial protein synthesis in mouse L-cells: effect of selective nicking of mitochondrial DNA.

R. Lansman, D. Clayton, 1975, Journal of molecular biology.

The mitochondrial DNA of drosophila melanogaster exists in two distinct and stable superhelical forms

J. Rubenstein, D. Brutlag, D. Clayton, 1977, Cell.

Pervasive CpG suppression in animal mitochondrial genomes.

D. A. Clayton, S Karlin, L R Cardon, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Identification of transcriptional regulatory elements in human mitochondrial DNA by linker substitution analysis

D. A. Clayton, J. N. Topper, D. Clayton, 1989, Molecular and cellular biology.

Altered mobility of polydeoxyribonucleotides in high resolution polyacrylamide gels due to removal of terminal phosphates.

D. Tapper, D. Clayton, 1981, Nucleic acids research.

Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7

D. A. Clayton, Brian S. Masters, L. Stohl, 1987, Cell.

Precise nucleotide location of the 5' ends of RNA-primed nascent light strands of mouse mitochondrial DNA.

D. A. Clayton, D. Tapper, D. Clayton, 1982, Journal of molecular biology.

Mechanism of mitochondrial DNA replication in mouse L-cells: kinetics of synthesis and turnover of the initiation sequence.

D. Bogenhagen, D. Clayton, 1978, Journal of molecular biology.

Replication of mitochondrial DNA in mouse L cells and their thymidine kinase - derivatives: displacement replication on a covalently-closed circular template.

D. A. Clayton, D. Robberson, D. Clayton, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Mitochondrial medicine – recent advances

C. Graff, N. Larsson, D. Clayton, 1999, Journal of internal medicine.

Initiation of Mitochondrial DNA Replication by Transcription and R-loop Processing*

D. Clayton, Daniel Y. Lee, 1998, The Journal of Biological Chemistry.

Purification of mitochondria by sucrose step density gradient centrifugation.

D. A. Clayton, G. Shadel, D. Clayton, 2014, Cold Spring Harbor protocols.

Impairment of mitochondrial transcription termination by a point mutation associated with the MELAS subgroup of mitochondrial encephalomyopathies

M. Parisi, J. Hess, J. L. Bennett, 1991, Nature.

Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths

J. E. Rinholm, T. Brown, B. G. Kopek, 2016, Glia.

Human mitochondrial transcription factor A and promoter spacing integrity are required for transcription initiation.

G. Shadel, D. Dairaghi, D. Clayton, 1995, Biochimica et biophysica acta.

Assignment of a yeast protein necessary for mitochondrial transcription initiation.

B. Xu, D. Clayton, 1992, Nucleic acids research.

The Alternatively Spliced Form of Human Mitochondrial Transcription Factor a Displays Altered DNA Binding Properties

G. Shadel, D. Dairaghi, D. Clayton, 1995 .

39 Mitochondria 1 DNA Replication

D. Clayton, 2005 .

39 DNA Replication

D. Clayton, 1996 .

Structure and chromosomal localization of the mouse mitochondrial transcription factor a gene (Tfam)

G. Barsh, N. Larsson, D. Clayton, 1997, Mammalian Genome.

Structure and function of the mitochondrial genome

D. Clayton, 1992, Journal of Inherited Metabolic Disease.

Vertebrate mitochondrial DNA-a circle of surprises.

D. Clayton, 2000, Experimental cell research.

Down-regulation of mitochondrial transcription factor A during spermatogenesis in humans.

G. Barsh, N. Larsson, A. Oldfors, 1997, Human molecular genetics.

Functional conservation of yeast mtTFB despite extensive sequence divergence.

D. A. Clayton, J. Carrodeguas, D. Bogenhagen, 1996, Gene expression.

Initiation of transcription from each of the two human mitochondrial promoters requires unique nucleotides at the transcriptional start sites.

J. Hixson, D. Clayton, 1985, Proceedings of the National Academy of Sciences of the United States of America.

In vitro transcription of human mitochondrial DNA. Identification of specific light strand transcripts from the displacement loop region.

M. Walberg, D. Clayton, 1983, The Journal of biological chemistry.

DNA Replication, Mitochondrial

D. Clayton, 2004 .

Concluding remarks: The mitochondrial DNA replication bubble has not burst.

D. A. Clayton, D. Bogenhagen, D. Clayton, 2003, Trends in biochemical sciences.

Isolation and characterization of a DNA primase from human mitochondria.

T. Wong, D. Clayton, 1985, The Journal of biological chemistry.

Absence of a pyrimidine dimer repair mechanism for mitochondrial DNA in mouse and human cells.

D. A. Clayton, E. Friedberg, J. N. Doda, 1975, Basic life sciences.

Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion.

D. A. Clayton, E. Holme, N. Larsson, 1994, Biochemical and biophysical research communications.

mechanism with alternative light-strand origins , not via a strand-coupled Replication of mitochondrial DNA occurs by strand displacement data

C. Bustamante, T. Brown, C. Cecconi, 2005 .

Replication of mouse L-cell mitochondrial DNA.

D. Bogenhagen, A. Gillum, D. Clayton, 1979, Cold Spring Harbor symposia on quantitative biology.

A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts.

E. Dufour, N. Larsson, K. Hultenby, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Cleavage of replicating forms of mitochondrial DNA by EcoRI endonuclease.

D. Robberson, J. Morrow, D. Clayton, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Mechanism of mitochondrial DNA replication in mouse L-cells: topology of circular daughter molecules and dynamics of catenated oligomer formation.

A. J. Berk, D. Clayton, 1976, Journal of molecular biology.

Replication of Mammalian Mitochondrial DNA

D. Clayton, 1983 .

Mechanism of mitochondrial DNA replication in mouse L cells: localization of alkali-sensitive sites at the two origins of replication.

D. A. Clayton, J. N. Doda, K. Margolin, 1981, Plasmid.

Mechanism of mitochondrial DNA replication in mouse L-cells. Replication of unicircular dimer molecules.

D. A. Clayton, D. Bogenhagen, C. Lowell, 1981, Journal of molecular biology.

THE UNIQUE MECHANISM OF ANIMAL MITOCHONDRIAL DNA REPLICATION

J. N. Doda, D. Clayton, 1980 .

The transcription map of mouse mitochondrial DNA

J. Battey, D. Clayton, 1978, Cell.

Mechanism of mitochondrial DNA replication in mouse L-cells: introduction of superhelical turns into newly replicated molecules.

D. A. Clayton, D. Bogenhagen, D. Clayton, 1978, Journal of molecular biology.

Pulse-labeled components in the replication of mitochondrial deoxyribonucleic acid.

D. Robberson, D. Clayton, 1973, The Journal of biological chemistry.

Displacement-loop replication initiation sequence in animal mitochondrial DNA exists as a family of discrete lengths.

A. Gillum, D. Clayton, A. M. Gillum, 1978, Proceedings of the National Academy of Sciences of the United States of America.

In vitro replication of mitochondrial DNA. Elongation of the endogenous primer sequence in D loop mitochondrial DNA by human DNA polymerase beta.

D. Eichler, T. S. Wang, D. Korn, 1977, Journal of Biological Chemistry.

Human mitochondrial transcription termination exhibits RNA polymerase independence and biased bipolarity in vitro.

D. A. Clayton, J. Shang, D. Clayton, 1994, The Journal of biological chemistry.

Heavy traffic at a dual-purpose human mitochondrial tRNA gene.

D. A. Clayton, D. Clayton, 1993, The Journal of clinical investigation.

A tridecamer DNA sequence supports human mitochondrial RNA 3'-end formation in vitro

D. A. Clayton, T. Christianson, D. Clayton, 1988, Molecular and Cellular Biology.

Regulation and function of the mitochondrial genome

S. Jeong-Yu, D. Clayton, 1996, Journal of Inherited Metabolic Disease.

Complex mitochondrial DNA in leukemic and normal human myeloid cells.

J. Vinograd, D. Clayton, 1969, Proceedings of the National Academy of Sciences of the United States of America.

The gene for ribosomal protein L7a-1 in Schizosaccharomyces pombe contains an intron after the initiation codon.

D. A. Clayton, A. Brennicke, A. Marchfelder, 1998, Biochimica et biophysica acta.

Approaches toward super-resolution fluorescence imaging of mitochondrial proteins using PALM.

Richard D. Fetter, Ariana N. Tkachuk, R. Fetter, 2010, Methods.

φX174 gene A protein does not cleave at a mouse mitochondrial DNA sequence homologous to the φX and G4 cleavage site

J. N. Doda, D. Clayton, 1981 .

S1 nuclease-specific nicking of mitochondrial DNA containing displacement loops.

D. Bogenhagen, C. Lowell, D. Clayton, 1978, Analytical biochemistry.

Properties of mitochondrial DNA metabolising enzymes; implications for chemotherapy.

D. A. Clayton, S. Eriksson, B. Xu, 1994, Advances in experimental medicine and biology.

Mitochondrial DNA gets the drift

D. Clayton, 1996, Nature Genetics.

Transcriptional mapping of the ribosomal RNA region of mouse L-cell mitochondrial DNA

Phillip Nagley, David A. Clayton, D. Clayton, 1980, Nucleic Acids Res..

Identification of the 3'-ends of the two mouse mitochondrial ribosomal RNAs. The 3'-end of 16 S ribosomal RNA contains nucleotides encoded by the gene for transfer RNALeuUUR.

D. A. Clayton, R. V. van Etten, J. W. Bird, 1983, The Journal of biological chemistry.

Stimulation of Mitochondrial Gene Expression and Proliferation of Mitochondria Following Impairment of Cellular Energy Transfer by Inhibition of the Phosphocreatine Circuit in Rat Hearts

R. Wiesner, T. Wallimann, J. D. Garman, 1999, Journal of bioenergetics and biomembranes.

Nucleotide assignment of alkali-sensitive sites in mouse mitochondrial DNA.

A. Brennicke, D. Clayton, 1981, The Journal of biological chemistry.

Identification of primary transcriptional start sites of mouse mitochondrial DNA: accurate in vitro initiation of both heavy- and light-strand transcripts

D. A. Clayton, D. Chang, D. Clayton, 1986, Molecular and cellular biology.

Roles for a promoter and RNA processing in the synthesis of mitochondrial displacement-loop strands.

D. Chang, R. Fisher, D. Clayton, 1987, Biochimica et biophysica acta.

Length heterogeneity of a conserved displacement-loop sequence in human mitochondrial DNA.

W. Hauswirth, D. Clayton, 1985, Nucleic acids research.

Superresolution Fluorescence Imaging of Mitochondrial Nucleoids Reveals Their Spatial Range, Limits, and Membrane Interaction

H. Hess, T. Brown, B. G. Kopek, 2011, Molecular and Cellular Biology.

A rapid, efficient method for purifying DNA-binding proteins. Denaturation-renaturation chromatography of human and yeast mitochondrial extracts.

T. Lisowsky, G. Breen, R. Fisher, 1991, The Journal of biological chemistry.

Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths

J. E. Rinholm, T. Brown, B. G. Kopek, 2016, Glia.

In situ localization of mitochondrial DNA replication in intact mammalian cells

D. Clayton, Alison F. Davis, 1996, The Journal of cell biology.

Isolation of mitochondria from animal tissue.

G. Shadel, D. Clayton, 2014, Cold Spring Harbor protocols.

Strand breakage in solutions of DNA and ethidium bromide exposed to visible light.

D. Clayton, P. A. Martens, 1977, Nucleic acids research.

The transcription map of human mitochondrial DNA implicates transfer RNA excision as a major processing event.

J. Battey, D. Clayton, 1980, The Journal of biological chemistry.

Purification of mitochondria by sucrose step density gradient centrifugation.

G. Shadel, D. Clayton, 2014, Cold Spring Harbor Protocols.

Mitochondrial-specific thymidine kinase.

B. Meyer, A. J. Berk, D. Clayton, 1973, Archives of biochemistry and biophysics.