Z. Zheng

发表

Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor–transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma

H. Fine, M. Raffeld, S. Rosenberg, 2019, Journal of immunotherapy.

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

J. Gartner, S. Rosenberg, T. Prickett, 2018, Nature Medicine.

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.

J. Gartner, S. Rosenberg, T. Prickett, 2016, The New England journal of medicine.

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

Tongguang Wang, Dolores J. Schendel, Richard A. Morgan, 2013, Journal of immunotherapy.

Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes

S. Rosenberg, R. Morgan, J. Yang, 2006, Science.

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

J. Gartner, S. Rosenberg, T. Prickett, 2018, Nature Medicine.

Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3.

S. Rosenberg, C. Klebanoff, J. Yang, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma.

H. Fine, Wei Zhang, S. Rosenberg, 2012, Human gene therapy.

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.

S. Rosenberg, R. Morgan, N. Restifo, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing

J. Gartner, S. Rosenberg, Frank J. Lowery, 2021, Journal for ImmunoTherapy of Cancer.

Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma

J. Gartner, V. Hill, S. Rosenberg, 2021, Journal for ImmunoTherapy of Cancer.

Immunogenicity of somatic mutations in human gastrointestinal cancers

J. Gartner, S. Rosenberg, S. Turcotte, 2015, Science.

Gene Expression Profiling using Nanostring Digital RNA Counting to Identify Potential Target Antigens for Melanoma Immunotherapy

S. Rosenberg, R. Morgan, D. Abate-Daga, 2013, Clinical Cancer Research.

Preferential survival of CD4+ T lymphocytes engineered with anti-human immunodeficiency virus (HIV) genes in HIV-infected individuals.

H Clifford Lane, J. Metcalf, M. Baseler, 2005, Human gene therapy.

Inhibition of viral gene expression and replication in mosquito cells by dsRNA-triggered RNA interference.

N. Caplen, R. Morgan, B. Falgout, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells

H. Fine, W. Burns, S. Rosenberg, 2014, Journal of Immunotherapy for Cancer.

Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers

J. Gartner, S. Sindiri, V. Hill, 2022, Science.

Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy

S. Rosenberg, Yong-Chen Lu, P. Robbins, 2019, Cancer Immunology Research.

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

J. Wargo, S. Rosenberg, R. Morgan, 2009, Cancer Immunology, Immunotherapy.

Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer

J. Gartner, S. Rosenberg, Yong-Chen Lu, 2019, The Journal of Immunology.

An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors.

J. Gartner, S. Rosenberg, T. Prickett, 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer

J. Gartner, S. Rosenberg, Yong-Chen Lu, 2017, Clinical Cancer Research.

Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors

Jonathan M. Hernandez, Chuong D. Hoang, C. Hoang, 2022, Cancer immunology research.

Adoptive cell therapy targeting common p53 neoantigens in human solid cancers

Chuong D. Hoang, C. Hoang, J. Gartner, 2021 .

The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion

A. Dutra, R. Morgan, D. Bellinger, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability.

Yangbing Zhao, S. Rosenberg, R. Morgan, 2006, Cancer research.

The position of the AUG start codon in MFG‐based γ‐retroviral vectors has a dramatic effect on translation‐dependent protein expression

W. Burns, R. Morgan, T. Frankel, 2011, The journal of gene medicine.

Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity

S. Rosenberg, R. Morgan, Zhili Zheng, 2015, Journal of Virology.

Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansion

S. Rosenberg, R. Morgan, S. Feldman, 2010, Cancer Immunology, Immunotherapy.

A novel chimeric antigen receptor against prostate stem cell antigen mediates tumor destruction in a humanized mouse model of pancreatic cancer.

W. Burns, S. Rosenberg, R. Morgan, 2014, Human gene therapy.

Development of Human Anti-Murine T-Cell Receptor Antibodies in Both Responding and Nonresponding Patients Enrolled in TCR Gene Therapy Trials

S. Rosenberg, R. Morgan, C. Lamers, 2010, Clinical Cancer Research.

high-throughput genotyping A set of canine interrepeat sequence PCR markers for

A. Dutra, G. Acland, J. Pelletier, 2015 .

Both CD4 and CD8 T Cells Mediate Equally Effective In Vivo Tumor Treatment When Engineered with a Highly Avid TCR Targeting Tyrosinase

W. Burns, J. Wargo, S. Rosenberg, 2010, The Journal of Immunology.

Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene.

K. Cornetta, T. Ried, S. Rosenberg, 2007, Blood.

A Herceptin-Based Chimeric Antigen Receptor with Modified Signaling Domains Leads to Enhanced Survival of Transduced T Lymphocytes and Antitumor Activity1

S. Rosenberg, M. Sadelain, R. Morgan, 2009, The Journal of Immunology.

Lymphocytes and Antitumor Activity Leads to Enhanced Survival of Transduced T Receptor with Modified Signaling Domains A Herceptin-Based Chimeric Antigen

S. Rosenberg, Z. Eshhar, Yangbing Zhao, 2009 .

Transduction of an HLA-DP4–restricted NY-ESO-1–specific TCR into Primary Human CD4+ Lymphocytes

S. Rosenberg, R. Morgan, Yangbing Zhao, 2006, Journal of immunotherapy.

High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation.

S. Rosenberg, R. Morgan, N. Restifo, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

A Novel Murine T-Cell Receptor Targeting NY-ESO-1

S. Rosenberg, R. Morgan, Mahadev Rao, 2014, Journal of immunotherapy.

A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas.

W. Burns, S. Rosenberg, R. Morgan, 2010, Cancer research.

Tumor-Infiltrating Lymphocytes Genetically Engineered with an Inducible Gene Encoding Interleukin-12 for the Immunotherapy of Metastatic Melanoma

Sadik H. Kassim, S. Rosenberg, R. Morgan, 2015, Clinical Cancer Research.

Primary Human Lymphocytes Transduced with NY-ESO-1 Antigen-Specific TCR Genes Recognize and Kill Diverse Human Tumor Cell Lines

Richard A. Morgan, Steven A. Rosenberg, Yangbing Zhao, 2005, The Journal of Immunology.

High Efficiency TCR Gene Transfer into Primary Human Lymphocytes Affords Avid Recognition of Melanoma Tumor Antigen Glycoprotein 100 and Does Not Alter the Recognition of Autologous Melanoma Antigens

S. Rosenberg, R. Morgan, P. Robbins, 2003, The Journal of Immunology.

Single and Dual Amino Acid Substitutions in TCR CDRs Can Enhance Antigen-Specific T Cell Functions

Bent K. Jakobsen, Richard A. Morgan, Steven A. Rosenberg, 2008, The Journal of Immunology.

Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation.

S. Rosenberg, R. Morgan, Zhili Zheng, 2009, Blood.

Recognition of Fresh Human Tumor by Human Peripheral Blood Lymphocytes Transduced with a Bicistronic Retroviral Vector Encoding a Murine Anti-p53 TCR

S. Rosenberg, R. Morgan, Yangbing Zhao, 2005, The Journal of Immunology.

High-Affinity TCRs Generated by Phage Display Provide CD4+ T Cells with the Ability to Recognize and Kill Tumor Cell Lines1

Yi Li, Bent K. Jakobsen, Richard A. Morgan, 2007, The Journal of Immunology.

Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions.

S. Rosenberg, R. Morgan, R. Hawley, 2005, Human gene therapy.

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.

S. Rosenberg, R. Morgan, David E. Paschon, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Gamma-retroviral vector design for the co-expression of artificial microRNAs and therapeutic proteins.

R. Morgan, D. Abate-Daga, Zhili Zheng, 2014, Nucleic acid therapeutics.

Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2.

S. Rosenberg, R. Morgan, K. Matsuda, 2008, Human gene therapy.

Adoptive Cell Transfer and Lymphodepleting Chemotherapy for the Treatment of Metastatic Melanoma

R. Morgan, K. Matsuda, M. Dudley, 2011 .

Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.

S. Rosenberg, R. Morgan, Yangbing Zhao, 2009, Human gene therapy.

Cell Lines Recognize and Kill Diverse Human Tumor with NY-ESO-1 Antigen-Specific TCR Genes Primary Human Lymphocytes Transduced

S. Rosenberg, R. Morgan, P. Robbins, 2005 .

Primary Human T Lymphocytes Engineered with a Codon-Optimized IL-15 Gene Resist Cytokine Withdrawal-Induced Apoptosis and Persist Long-Term in the Absence of Exogenous Cytokine1

S. Rosenberg, R. Morgan, M. Hughes, 2005, The Journal of Immunology.

Exogenous Cytokine Persist Long-Term in the Absence of Cytokine Withdrawal-Induced Apoptosis and with a Codon-Optimized IL-15 Gene Resist Primary Human T Lymphocytes Engineered

S. Rosenberg, R. Morgan, Zhili Zheng, 2005 .

Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling.

S. Rosenberg, R. Morgan, N. Restifo, 2007, Cancer research.

Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity

S. Rosenberg, R. Morgan, Yangbing Zhao, 2009, Gene Therapy.

Lines Ability to Recognize and Kill Tumor Cell T Cells with the + Display Provide CD 4 High-Affinity TCRs Generated by Phage Rosenberg and

B. Jakobsen, R. Morgan, P. Robbins, 2007 .

Development of a T Cell Receptor Targeting an HLA-A*0201 Restricted Epitope from the Cancer-Testis Antigen SSX2 for Adoptive Immunotherapy of Cancer

S. Rosenberg, D. Speiser, R. Morgan, 2014, PloS one.

Evaluation of &ggr;-Retroviral Vectors That Mediate the Inducible Expression of IL-12 for Clinical Application

S. Rosenberg, R. Morgan, M. Dudley, 2012, Journal of immunotherapy.

Protein L: a novel reagent for the detection of Chimeric Antigen Receptor (CAR) expression by flow cytometry

R. Morgan, Zhili Zheng, N. Chinnasamy, 2012, Journal of Translational Medicine.

Protein L: a novel reagent for the detection of Chimeric Antigen Receptor (CAR) expression by flow cytometry

R. Morgan, N. Chinnasamy, Z. Zheng, 2012, Journal of Translational Medicine.

The up-regulation of long non-coding RNA CCAT2 indicates a poor prognosis for prostate cancer and promotes metastasis by affecting epithelial-mesenchymal transition.

Xiaolong He, Gang Zhang, Jinfeng Zheng, 2016, Biochemical and biophysical research communications.

A Phase I study of an HLA-DPB1*0401-restricted T cell receptor targeting MAGE-A3 for patients with metastatic cancers

S. Rosenberg, C. Klebanoff, J. Yang, 2015, Journal of Immunotherapy for Cancer.

Gene Expression Profiling using Nanostring Digital RNA Counting to Identify Potential Target Antigens for Melanoma Immunotherapy

S. Rosenberg, R. Morgan, D. Abate-Daga, 2013, Clinical Cancer Research.