X. Dong

W. Zhou, Jian-Hua Dong, Qiang Shi, 2013, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Clinical and familial characteristics of ten chinese patients with fatal family insomnia.

W. Zhou, Qiang Shi, Cao Chen, 2012, Biomedical and environmental sciences : BES.

Genetic Prion Disease: Insight from the Features and Experience of China National Surveillance for Creutzfeldt-Jakob Disease

Wei Zhou, Qiang Shi, Cao Chen, 2021, Neuroscience Bulletin.

Analysis of 12 Chinese Patients with Proline-to-Leucine Mutation at Codon 102-Associated Gerstmann-Sträussler-Scheinker Disease

W. Zhou, Jing Wang, Qiang Shi, 2019, Journal of clinical neurology.

Low activity of complement in the cerebrospinal fluid of the patients with various prion diseases

W. Zhou, Qiang Shi, Cao Chen, 2016, Infectious Diseases of Poverty.

Dysfunction of microtubule-associated proteins of MAP2/tau family in Prion disease

Jin Zhang, Xiao-Ping Dong, X. Dong, 2012, Prion.

The Prepared Tau Exon-Specific Antibodies Revealed Distinct Profiles of Tau in CSF of the Patients with Creutzfeldt-Jakob Disease

W. Zhou, Qiang Shi, Cao Chen, 2010, PloS one.

The Epidemiological, Clinical, and Laboratory Features of Sporadic Creutzfeldt-Jakob Disease Patients in China: Surveillance Data from 2006 to 2010

W. Zhou, Qiang Shi, Cao Chen, 2011, PloS one.

Characteristics of Chinese patients with genetic CJD who have E196A or E196K mutation in PRNP: comparative analysis of patients identified in the Chinese National CJD Surveillance System

Wei Zhou, Qiang Shi, Cao Chen, 2021, BMJ Open.

Rare genetic Creutzfeldt-Jakob disease with T188K mutation: analysis of clinical, genetic and laboratory features of30 Chinese patients

W. Zhou, Qiang Shi, Cao Chen, 2017, Journal of Neurology, Neurosurgery, and Psychiatry.

The first Chinese case of Creutzfeldt-Jakob disease with mutation of E200K in PRNP.

W. Zhou, Qiang Shi, Chen Gao, 2010, Biomedical and environmental sciences : BES.

Human Prion disease with a T188K mutation in Chinese: a case report

W. Zhou, Qiang Shi, Chen Gao, 2009, Cases journal.

Calmodulin level is significantly increased in the cerebrospinal fluid of patients with sporadic Creutzfeldt‐Jakob disease

Qiang Shi, Cao Chen, Xiao-Ping Dong, 2020, European journal of neurology.

A Chinese Creutzfeldt-Jakob disease patient with E196K mutation in PRNP

W. Zhou, Qiang Shi, Cao Chen, 2011, Prion.

Expert Consensus on Clinical Diagnostic Criteria for Fatal Familial Insomnia

S. Gauthier, Y. Huang, Xiao-Ping Dong, 2018, Chinese medical journal.

Clinical and Laboratory Features of Three Rare Chinese V210I gCJD Patients

Qiang Shi, Cao Chen, Chen Gao, 2020, Pathogens.

Fatal Familial Insomnia: Insight of the Most Common Genetic Prion Disease in China Based On the Analysis of 40 Patients

W. Zhou, Jing Wang, Qiang Shi, 2018 .

Quality evaluation for the surveillance system of human prion diseases in China based on the data from 2010 to 2016

W. Zhou, Jing Wang, Qiang Shi, 2016, Prion.

Analyses of the Survival Time and the Influencing Factors of Chinese Patients with Prion Diseases Based on the Surveillance Data from 2008–2011

W. Zhou, Qiang Shi, Cao Chen, 2013, PloS one.

Surveillance for Creutzfeldt-Jakob disease in China from 2006 to 2007

N. Xiang, W. Zhou, Qiang Shi, 2008, BMC public health.

Preparation of human tau exon-2- and -10-specific monoclonal antibodies for the recognition of brain tau proteins in various mammals.

Qiang Shi, Cao Chen, K. Xiao, 2015, International journal of molecular medicine.

Different expression patterns of CK2 subunits in the brains of experimental animals and patients with transmissible spongiform encephalopathies

B. Shan, Qiang Shi, Chen Gao, 2008, Archives of Virology.

Interaction between 14-3-3β and PrP influences the dimerization of 14-3-3 and fibrillization of PrP106-126.

Juan Song, Qiang Shi, Cao Chen, 2014, The international journal of biochemistry & cell biology.

Assessment of the Sensitivity and Specificity of the Established Real-time Quaking-induced Conversion (RT-QuIC) Technique in Chinese CJD Surveillance.

X. Yang, Qiang Shi, K. Xiao, 2020, Biomedical and environmental sciences : BES.

Comparative Analysis of The Characteristics of The Chinese gCJD Patients With E196A and E196K Mutation in PRNP

Qiang Shi, Cao Chen, Chen Gao, 2021 .

Cerebrospinal Fluids from Patients with Five Common Genetic Prion Diseases in China Display Distinct Reactivities in the RT-QuIC Assays.

Wei Zhou, Qiang Shi, Cao Chen, 2021, Biomedical and environmental sciences : BES.

A Chinese patient with the clinical features of Parkinson’s disease contains a single copy of octarepeat deletion in PRNP case report

Wei Zhou, Qiang Shi, Cao Chen, 2021, Prion.

The low levels of nerve growth factor and its upstream regulatory kinases in prion infection is reversed by resveratrol

Jing Wang, Qiang Shi, Cao Chen, 2019, Neuroscience Research.

Stilbene compounds inhibit the replications of various strains of prions in the levels of cell culture, PMCA and RT-QuIC possibly via molecular binding.

Jing Wang, Qiang Shi, Cao Chen, 2020, ACS chemical neuroscience.

Generation and characterization of two strains of transgene mice expressing chimeric MiniSOG-MusPrP

Qiang Shi, K. Xiao, Xuehua Yang, 2020, Journal of Neuroscience Methods.

IP10, KC and M-CSF Are Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents

Qiang Shi, Cao Chen, Xiao-Ping Dong, 2020, Virologica Sinica.

Enhanced mitophagy activity in prion infected cultured cells and prion infected experimental mice via Pink1/Parkin dependent mitophagy pathway.

Qiang Shi, Xiao-Ping Dong, K. Xiao, 2020, ACS chemical neuroscience.

Alternative complement pathway is activated in the brains of scrapie-infected rodents

Jing Wang, Qiang Shi, Cao Chen, 2019, Medical Microbiology and Immunology.

T188K-Familial Creutzfeldt–Jacob Disease, Predominant Among Chinese, has a Reactive Pattern in CSF RT-QuIC Different from D178N-Fatal Familial Insomnia and E200K-Familial CJD

W. Zhou, Qiang Shi, Cao Chen, 2019, Neuroscience Bulletin.

Significant enhanced expressions of aquaporin-1, -4 and -9 in the brains of various prion diseases

Qiang Shi, Cao Chen, Chen Gao, 2019, Prion.

Stimulations of the Culture Medium of Activated Microglia and TNF-Alpha on a Scrapie-Infected Cell Line Decrease the Cell Viability and Induce Marked Necroptosis That Also Occurs in the Brains from the Patients of Human Prion Diseases.

Jing Wang, Qiang Shi, Cao Chen, 2018, ACS chemical neuroscience.

Evaluation of the effect of various main elements on the PrPSc detection by real-time quaking-induced conversion assay

W. Zhou, Jing Wang, Qiang Shi, 2018, International journal of molecular medicine.

Remarkable increases of α1-antichymotrypsin in brain tissues of rodents during prion infection

Qiang Shi, Cao Chen, Xiao-Ping Dong, 2017, Prion.

Aberrant alterations of the expressions and S-nitrosylation of calmodulin and the downstream factors in the brains of the rodents during scrapie infection

Qiang Shi, Cao Chen, Xiao-Ping Dong, 2017, Prion.

Comparative proteomics analyses for 139A and ME7 scrapie infected mice brains in the middle and terminal stages

W. Zhou, Qiang Shi, Cao Chen, 2017, Proteomics. Clinical applications.

Clinical and laboratory features of 14 young Chinese probable sCJD patients

W. Zhou, Jing Wang, Qiang Shi, 2017, Prion.

Increases of Galectin-1 and its S-nitrosylated form in the Brain Tissues of Scrapie-Infected Rodent Models and Human Prion Diseases

Qiang Shi, Cao Chen, Yanjun Guo, 2016, Molecular Neurobiology.

The Brain NO Levels and NOS Activities Ascended in the Early and Middle Stages and Descended in the Terminal Stage in Scrapie-Infected Animal Models

W. Zhou, Qiang Shi, Cao Chen, 2017, Molecular Neurobiology.

Aberrant Alterations of Mitochondrial Factors Drp1 and Opa1 in the Brains of Scrapie Experiment Rodents

W. Zhou, Qiang Shi, Cao Chen, 2017, Journal of Molecular Neuroscience.

Down-regulation of brain-derived neurotrophic factor and its signaling components in the brain tissues of scrapie experimental animals.

Jing Wang, Qiang Shi, Cao Chen, 2016, The international journal of biochemistry & cell biology.

Remarkable impairment of Wnt/β‐catenin signaling in the brains of the mice infected with scrapie agents

Jing Wang, Qiang Shi, C. Tian, 2016, Journal of neurochemistry.

Re-infection of the prion from the scrapie-infected cell line SMB-S15 in three strains of mice, CD1, C57BL/6 and Balb/c

Jing Wang, Qiang Shi, Cao Chen, 2016, International journal of molecular medicine.

Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrPSc Accumulation In Vitro and Prion Infectivity In Vivo

Jing Wang, Qiang Shi, Jin Zhang, 2016, Molecular Neurobiology.

Proteomic Analyses for the Global S-Nitrosylated Proteins in the Brain Tissues of Different Human Prion Diseases

W. Zhou, Jing Wang, Qiang Shi, 2016, Molecular Neurobiology.

The Levels of Tau Isoforms Containing Exon-2 and Exon-10 Segments Increased in the Cerebrospinal Fluids of the Patients with Sporadic Creutzfeldt-Jakob Disease

W. Zhou, Wei Zhou, Jing Wang, 2015, Molecular Neurobiology.

Remarkable Activation of the Complement System and Aberrant Neuronal Localization of the Membrane Attack Complex in the Brain Tissues of Scrapie-Infected Rodents

Jing Wang, Qiang Shi, Cao Chen, 2015, Molecular Neurobiology.

Scrapie Infection in Experimental Rodents and SMB-S15 Cells Decreased the Brain Endogenous Levels and Activities of Sirt1

Jing Wang, Qiang Shi, Cao Chen, 2014, Journal of Molecular Neuroscience.

Remarkable reductions of PAKs in the brain tissues of scrapie-infected rodent possibly linked closely with neuron loss

Jing Wang, Qiang Shi, Cao Chen, 2014, Medical Microbiology and Immunology.

Infection of Prions and Treatment of PrP106–126 Alter the Endogenous Status of Protein 14-3-3 and Trigger the Mitochondrial Apoptosis Possibly via Activating Bax Pathway

Juan Song, Qiang Shi, Shao-Bin Wang, 2014, Molecular Neurobiology.

Significant Reduction of the GLUT3 Level, but not GLUT1 Level, Was Observed in the Brain Tissues of Several Scrapie Experimental Animals and Scrapie-Infected Cell Lines

Qiang Shi, Cao Chen, Yin Xu, 2013, Molecular Neurobiology.

Abnormally Upregulated αB-crystallin Was Highly Coincidental with the Astrogliosis in the Brains of Scrapie-Infected Hamsters and Human Patients with Prion Diseases

Qiang Shi, Yin Xu, Jin Zhang, 2013, Journal of Molecular Neuroscience.

Brain microglia were activated in sporadic CJD but almost unchanged in fatal familial insomnia and G114V genetic CJD

Qiang Shi, Cao Chen, Yin Xu, 2013, Virology Journal.

Abortive Cell Cycle Events in the Brains of Scrapie-Infected Hamsters with Remarkable Decreases of PLK3/Cdc25C and Increases of PLK1/Cyclin B1

Qiang Shi, Shao-Bin Wang, Cao Chen, 2013, Molecular Neurobiology.

Global transcriptional profiling of the postmortem brain of a patient with G114V genetic Creutzfeldt-Jakob disease.

Qiang Shi, Cao Chen, Yin Xu, 2013, International journal of molecular medicine.

Comparative Analysis of Gene Expression Profiles Between Cortex and Thalamus in Chinese Fatal Familial Insomnia Patients

H. Kretzschmar, W. Xiang, Qiang Shi, 2013, Molecular Neurobiology.

Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction

Yan Guo, Chen Gao, Chan Tian, 2012, Virology Journal.

Reduction of protein kinase MARK4 in the brains of experimental scrapie rodents and human prion disease correlates with deposits of PrP(Sc).

Qiang Shi, Shao-Bin Wang, Cao Chen, 2012, International journal of molecular medicine.

Co-expressions of Casein Kinase 2 (CK2) Subunits Restore the Down-Regulation of Tubulin Levels and Disruption of Microtubule Structures Caused by PrP Mutants

Qiang Shi, Shao-Bin Wang, Cao Chen, 2012, Journal of Molecular Neuroscience.

Protein Disulfide Isomerase Regulates Endoplasmic Reticulum Stress and the Apoptotic Process during Prion Infection and PrP Mutant-Induced Cytotoxicity

Qiang Shi, Shao-Bin Wang, Cao Chen, 2012, PloS one.

The diversities of PrPSc distributions and pathologic changes in various brain regions from a Chinese patient with G114V genetic CJD

Qiang Shi, Cao Chen, Chen Gao, 2012, Neuropathology : official journal of the Japanese Society of Neuropathology.

Remarkable Reduction of MAP2 in the Brains of Scrapie-Infected Rodents and Human Prion Disease Possibly Correlated with the Increase of Calpain

Qiang Shi, Shao-Bin Wang, Cao Chen, 2012, PloS one.

The first Chinese case of Creutzfeldt-Jakob disease patient with R208H mutation in PRNP

W. Zhou, Qiang Shi, Cao Chen, 2011, Prion.

A Novel PrP Partner HS-1 Associated Protein X-1 (HAX-1) Protected the Cultured Cells Against the Challenge of H2O2

Qiang Shi, Y. Jing, Cao Chen, 2011, Journal of Molecular Neuroscience.

Familial CJD Associated PrP Mutants within Transmembrane Region Induced Ctm-PrP Retention in ER and Triggered Apoptosis by ER Stress in SH-SY5Y Cells

Kun Xu, Qiang Shi, Cao Chen, 2011, PloS one.

Cytosolic PrP Induces Apoptosis of Cell by Disrupting Microtubule Assembly

Qiang Shi, Y. Jing, Chen Gao, 2011, Journal of Molecular Neuroscience.

Human Prion Protein Mutants with Deleted and Inserted Octarepeats Undergo Different Pathways to Trigger Cell Apoptosis

Qiang Shi, Cao Chen, C. Tian, 2011, Journal of Molecular Neuroscience.

Clinical, histopathological and genetic studies in a family with fatal familial insomnia.

Bian-Li Xu, W. Zhou, B. Shan, 2010, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Cytosolic prion protein induces apoptosis in human neuronal cell SH-SY5Y via mitochondrial disruption pathway.

Kun Xu, Qiang Shi, Chen Gao, 2009, BMB reports.

PrP(Sc) of scrapie 263K propagates efficiently in spleen and muscle tissues with protein misfolding cyclic amplification.

Kun Xu, B. Shan, Qiang Shi, 2009, Virus research.

The propagation of hamster‐adapted scrapie PrPSc can be enhanced by reduced pyridine nucleotide in vitro

Kun Xu, Chen Gao, C. Tian, 2009, The FEBS journal.

Human prion disease with a G114V mutation and epidemiological studies in a Chinese family: a case series

Qiang Shi, Chen Gao, C. Tian, 2008, Journal of medical case reports.

The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro.

Xiao-Fan Wang, B. Shan, Jun Han, 2008, Archives of biochemistry and biophysics.

Molecular interaction between prion protein and GFAP both in native and recombinant forms in vitro

B. Shan, Jun Han, Bao-yun Zhang, 2008, Medical Microbiology and Immunology.

Human tau protein forms complex with PrP and some GSS- and fCJD-related PrP mutants possess stronger binding activities with tau in vitro

Xiao-Fan Wang, B. Shan, Chen Gao, 2008, Molecular and Cellular Biochemistry.

Activation of Innate Immunity and Autophagy in Brain Tissues with Prion Disease and Degradation of Abnormal PrPs in Cells — China’s Studies

Wei Zhou, Qiang Shi, Cao Chen, 2022, China CDC weekly.

Accumulation of Prion and Abnormal Prion Protein Induces Hyperphosphorylation of α-Synuclein in the Brain Tissues from Prion Diseases and in the Cultured Cells.

Qiang Shi, Cao Chen, Xiao-Ping Dong, 2021, ACS chemical neuroscience.

Therapeutic implications of prion diseases

Cao Chen, X. Dong, Xiao-Ping Dong, 2020 .

Activation of IP10/CXCR3 signaling with highly coincidental with PrPSc deposit in the brains of scrapie infected mice

Qiang Shi, Cao Chen, Chao Hu, 2022, bioRxiv.

Global profiles of a cetylated proteins in the brains of scrapie agents 139A- and ME7-infected mice collected at mid-early, mid-late and terminal stage

Qiang Shi, Cao Chen, K. Xiao, 2020 .

The associations of two SNPs in miRNA-146a and one SNP in ZBTB38-RASA2 with the disease susceptibility and the clinical features of the Chinese patients of sCJD and FFI

Wei Zhou, Jing Wang, Qiang Shi, 2018, Prion.

Extensive Disturbances of Intracellular Components and Dysfunctions of Biological Pathways in the Brain Tissues During Prion Infection — China’s Studies

Wei Zhou, Qiang Shi, Cao Chen, 2022, China CDC weekly.

Optimization of the isolation and enrichment of S-nitrosylated proteins from brain tissues of rodents and humans with various prion diseases for iTRAQ-based proteomics.

Qiang Shi, Cao Chen, Chen Gao, 2015, International journal of molecular medicine.

Dynamic analyses of PrP and PrP(Sc) in brain tissues of golden hamsters infected with scrapie strain 263K revealed various PrP forms.

Xiao-bo Zhou, Chen Gao, Jin Zhang, 2004, Biomedical and environmental sciences : BES.

Establishment of a Special Platform for the Research of Prion and the Diagnosis of Human Prion Disease — China’s Studies

Wei Zhou, Qiang Shi, Cao Chen, 2022, China CDC weekly.

Different Aberrant Changes of mGluR5 and Its Downstream Signaling Pathways in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents

Qiang Shi, Cao Chen, K. Xiao, 2022, Frontiers in Cell and Developmental Biology.

IP10, KC and M-CSF Are Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents

Wei Zhou, Qiang Shi, Cao Chen, 2020, Virologica Sinica.

Decrease of RyR2 in the prion infected cell line and in the brains of the scrapie infected mice models and the patients of human prion diseases

W. Zhou, Jing Wang, Qiang Shi, 2018, Prion.

Reduction of NF-κB (p65) in Scrapie-Infected Cultured Cells and in the Brains of Scrapie-Infected Rodents.

W. Zhou, Jing Wang, Qiang Shi, 2017, ACS chemical neuroscience.

Manganese-induced changes of the biochemical characteristics of the recombinant wild-type and mutant PrPs

Kun Xu, Qiang Shi, Cao Chen, 2009, Medical Microbiology and Immunology.

PRNP Sequences of Tibetan Antelope, Blue Sheep, and Plateau Pika from the Qinghai-Tibet Plateau and Reactivity of PrP Proteins to Rodent-Adapted Scrapie Strains in RT-QuIC and PMCA

X. Yang, Qiang Shi, K. Xiao, 2023, Zoonoses.

Enhanced M-CSF/CSF1R Signaling Closely Associates with PrPSc Accumulation in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents

Qiang Shi, Cao Chen, Xiao-Ping Dong, 2022, Molecular Neurobiology.

Successive passaging of the scrapie strains, ME7-ha and 139A-ha, generated by the interspecies transmission of mouse-adapted strains into hamsters markedly shortens the incubation times, but maintains their molecular and pathological properties.

Qiang Shi, Cao Chen, Chen Gao, 2015, International journal of molecular medicine.

Abnormal Activation of Microglia Accompanied with Disrupted CX3CR1/CX3CL1 Pathway in the Brains of the Hamsters Infected with Scrapie Agent 263K

Qiang Shi, Shao-Bin Wang, Cao Chen, 2013, Journal of Molecular Neuroscience.

Case Report: Genetic Creutzfeldt–Jakob Disease With a G114V Mutation and One Octapeptide Repeat Deletion as a Mimic of Frontotemporal Dementia

X. Lin, Hongzhi Guan, Qiang Shi, 2022, Frontiers in Neurology.

CtmPrP and ER stress

Qiang Shi, Xiao-Ping Dong, X. Dong, 2011 .

(Ctm)PrP and ER stress: a neurotoxic mechanism of some special PrP mutants.

Qiang Shi, Xiao-Ping Dong, X. Dong, 2011, Prion.

Removal of the glycosylation of prion protein provokes apoptosis in SF126.

Xiao-Fan Wang, Chen Gao, Yang Yang, 2007, Journal of biochemistry and molecular biology.

Abnormally Upregulated αB-crystallin Was Highly Coincidental with the Astrogliosis in the Brains of Scrapie-Infected Hamsters and Human Patients with Prion Diseases

Qiang Shi, Yin Xu, Jin Zhang, 2013, Journal of Molecular Neuroscience.

Abnormal Activation of Microglia Accompanied with Disrupted CX3CR1/CX3CL1 Pathway in the Brains of the Hamsters Infected with Scrapie Agent 263K

Qiang Shi, Shao-Bin Wang, Cao Chen, 2013, Journal of Molecular Neuroscience.

Overexpression of p62/SQSTM1 promotes the degradations of abnormally accumulated PrP mutants in cytoplasm and relieves the associated cytotoxicities via autophagy–lysosome-dependent way

Jing Wang, Qiang Shi, Cao Chen, 2014, Medical Microbiology and Immunology.

Evaluation of the disease burden of sporadic Creutzfeldt-Jacob disease with the surveillance data from 2013 to 2017 in China

Wei Zhou, Qiang Shi, Cao Chen, 2020 .

[Interaction between various 14-3-3beta segments and PrP in vitro].

W. Zhou, Juan Song, C. Tian, 2010, Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology.

Molecular Interaction between PrP Protein and the Signal Protein 14-3-3β

Cao Chen, C. Tian, Jun Han, 2009 .

[Molecular interaction between PrP protein and the signal protein 14-3-3 beta].

Cao Chen, C. Tian, Jun Han, 2009, Bing du xue bao = Chinese journal of virology.

T188K-Familial Creutzfeldt–Jacob Disease, Predominant Among Chinese, has a Reactive Pattern in CSF RT-QuIC Different from D178N-Fatal Familial Insomnia and E200K-Familial CJD

Wei Zhou, Qiang Shi, Cao Chen, 2019, Neuroscience Bulletin.

Apparent Reduction of ADAM10 in Scrapie-Infected Cultured Cells and in the Brains of Scrapie-Infected Rodents

W. Zhou, Wei Zhou, Jing Wang, 2014, Molecular Neurobiology.

Protein Misfolding Cyclic Amplification Cross-Species Products of Mouse-Adapted Scrapie Strain 139A and Hamster-Adapted Scrapie Strain 263K with Brain and Muscle Tissues of Opposite Animals Generate Infectious Prions

J. Zhang, Qiang Shi, Chen Gao, 2016, Molecular Neurobiology.

Scrapie Infection in Experimental Rodents and SMB-S15 Cells Decreased the Brain Endogenous Levels and Activities of Sirt1

Jing Wang, Qiang Shi, Cao Chen, 2015, Journal of Molecular Neuroscience.

Apparent Reduction of ADAM10 in Scrapie-Infected Cultured Cells and in the Brains of Scrapie-Infected Rodents

W. Zhou, Jing Wang, Qiang Shi, 2014, Molecular Neurobiology.

Significant Reduction of the GLUT3 Level, but not GLUT1 Level, Was Observed in the Brain Tissues of Several Scrapie Experimental Animals and Scrapie-Infected Cell Lines

Qiang Shi, Cao Chen, Yin Xu, 2014, Molecular Neurobiology.

Disruption of Glycosylation Enhances Ubiquitin-Mediated Proteasomal Degradation of Shadoo in Scrapie-Infected Rodents and Cultured Cells

Qiang Shi, Cao Chen, Yin Xu, 2014, Molecular Neurobiology.

A Patient With Creutzfeldt-Jakob Disease With an Insertion of 7 Octa-Repeats in the PRNP Gene: Molecular Characteristics and Clinical Features

Xiao-Fan Wang, Wei⁃qin Zhao, Qiang Shi, 2008, The American journal of the medical sciences.

Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China

Qiang Shi, Xiao-Ping Dong, K. Xiao, 2019, Prion.

Comparative Analysis of Gene Expression Profiles Between Cortex and Thalamus in Chinese Fatal Familial Insomnia Patients

H. Kretzschmar, W. Xiang, Qiang Shi, 2013, Molecular Neurobiology.

Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a group of transmissible and rapidly progressive neurodegenerative diseases including Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI) in humans, bovine spongiform encephalopathy (BSE) in cattle, scrapi

Jing Wang, Qiang Shi, Cao Chen, 2016 .

Brain microglia were activated in sporadic CJD but almost unchanged in fatal familial insomnia and G114V genetic CJD

Qiang Shi, Cao Chen, Yin Xu, 2013, Virology Journal.

Establishment of hamster- and human-PRNP transgenic mice.

Qiang Shi, Y. Jing, Chen Gao, 2011, Biomedical and environmental sciences : BES.

Expression of prion protein is closely associated with pathological and clinical progression and abnormalities of p53 in head and neck squamous cell carcinomas.

J. Ji, Qiang Shi, Xiao-Ping Dong, 2016, Oncology reports.

PrP octarepeats region determined the interaction with caveolin-1 and phosphorylation of caveolin-1 and Fyn

Qiang Shi, Y. Jing, Shao-Bin Wang, 2013, Medical Microbiology and Immunology.

[Study on the characteristics of patients with Creutzfeldt-Jakob disease under 2008 surveillance data in China].

W. Zhou, Qiang Shi, Chen Gao, 2009, Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.

Impact of COVID-19 Pandemic on Patients With Neurodegenerative Diseases

Cao Chen, Xiao-Ping Dong, Chao Hu, 2021, Frontiers in Aging Neuroscience.

Difference of geographic distributions of the Chinese patients with prion diseases in the permanent resident places and referring places

Qiang Shi, Xiao-Ping Dong, K. Xiao, 2022, Prion.

Treatment of scrapie pathogen 263K with tetracycline partially abolishes protease-resistant activity in vitro and reduces infectivity in vivo.

Xiao-Fan Wang, Wei⁃qin Zhao, Jin Zhang, 2007, Biomedical and environmental sciences : BES.

Flotillin-1 Mediates PrPC Endocytosis in the Cultured Cells During Cu2+ Stimulation Through Molecular Interaction

Qiang Shi, Shao-Bin Wang, Yin Xu, 2013, Molecular Neurobiology.

PrP octarepeats region determined the interaction with caveolin-1 and phosphorylation of caveolin-1 and Fyn

Qiang Shi, Y. Jing, Shao-Bin Wang, 2013, Medical Microbiology and Immunology.

The distribution of human papillomavirus in tissues from patients with head and neck squamous cell carcinoma.

Qiang Shi, Cao Chen, Xiao-Ping Dong, 2012, Oncology reports.

Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX1

Qiang Shi, C. Tian, Xiao-Ping Dong, 2008, Acta Pharmacologica Sinica.

Operational research capacity building through the Structured Operational Research Training Initiative (SORT-IT) in China: implementation, outcomes and challenges

M. Oo, E. Geoffroy, Guomin Zhang, 2021, Infectious Diseases of Poverty.

Epidemiological investigation of human papillomavirus infection in men attending a sexually transmitted disease clinic in Hangzhou area.

Xiao-Ping Dong, A. Xu, Hong Shen, 2006, Biomedical and environmental sciences : BES.

Efficient and quick inactivation of SARS coronavirus and other microbes exposed to the surfaces of some metal catalysts.

Min Yang, Qingxiang Yang, Chen Gao, 2005, Biomedical and environmental sciences : BES.

HPV-2 Isolates from Patients with Huge Verrucae Vulgaris Possess Stronger Promoter Activities

Chen Gao, Xiao-Ping Dong, Jun Han, 2007, Intervirology.

Intra-host Ebola viral adaption during human infection

Hui Jiang, G. Gao, Xiang-rong Zhao, 2019, Biosafety and Health.

A point mutation in the DNA-binding domain of HPV-2 E2 protein increases its DNA-binding capacity and reverses its transcriptional regulatory activity on the viral early promoter

Qiang Shi, Chen Gao, C. Tian, 2012, BMC Molecular Biology.

Avian influenza A(H5N1) viruses can directly infect and replicate in human gut tissues.

Weizhong Yang, Hongjie Yu, Zijian Feng, 2010, The Journal of infectious diseases.

Analyses of the mitochondrial mutations in the Chinese patients with sporadic Creutzfeldt–Jakob disease

C. Chen, W. Zhou, Qiang Shi, 2014, European Journal of Human Genetics.

PrPSc Inhibition and Cellular Protection of DBL on a Prion-Infected Cultured Cell via Multiple Pathways

Qiang Shi, Cao Chen, Zhi-Bao Chen, 2022, Molecular neurobiology.

Construction of prophylactic human papillomavirus type 16 L1 capsid protein vaccine delivered by live attenuated Shigella flexneri strain sh42.

Xiao-feng Yang, Yili Wang, L. Si, 2005, Acta biochimica et biophysica Sinica.

Rapid Global Spread of the SARS-CoV-2 Delta (B.1.617.2) Variant: Spatiotemporal Variation and Public Health Impact

Qiang Shi, X. Dong, Xiao-Ping Dong, 2021, Zoonoses.

Aberrant SENP1-SUMO-Sirt3 Signaling Causes the Disturbances of Mitochondrial Deacetylation and Oxidative Phosphorylation in Prion-Infected Animal and Cell Models.

Qiang Shi, Cao Chen, K. Xiao, 2023, ACS chemical neuroscience.

Development of a multiplex PCR method for detecting and typing human papillomaviruses in verrucae vulgaris.

Qiang Shi, Chen Gao, Xiao-Ping Dong, 2008, Journal of virological methods.

Co-expressions of Casein Kinase 2 (CK2) Subunits Restore the Down-Regulation of Tubulin Levels and Disruption of Microtubule Structures Caused by PrP Mutants

Qiang Shi, Shao-Bin Wang, Cao Chen, 2013, Journal of Molecular Neuroscience.

Analysis on Health-related Quality of Life of 180 Chinese Patients with Sporadic Creutzfeldt-Jakob Disease

Wei Zhou, Qiang Shi, Cao Chen, 2020 .

One Hundred Years of Influenza Since the 1918 Pandemic — Is China Prepared Today?

R. Ren, Zijian Feng, Dayan Wang, 2019, China CDC weekly.

[Chlamydia-like and coronavirus-like agents found in dead cases of atypical pneumonia by electron microscopy].

Wei-min Zhou, L. Ren, Wenqing Xu, 2003, Zhonghua yi xue za zhi.

Redox induces diverse effects on recombinant human wild-type PrP and mutated PrP with inserted or deleted octarepeats.

W. Zhou, Qiang Shi, Cao Chen, 2018, International journal of molecular medicine.

SARS: clinical virology and pathogenesis

M. Peiris, J. Nicholls, Xiao-Ping Dong, 2003, Respirology.

Establishment of a sandwich ELISA method for detection of vascular endothelial growth factor in serum samples of hepatocellular carcinoma patients.

B. Shan, Qiang Shi, Chen Gao, 2008, Biomedical and environmental sciences : BES.

Epidemiological Characteristics of Notifiable Infectious Diseases among Foreign Cases in China, 2004–2017

Yu Qin, G. Gao, Ji Wang, 2020, Biomedical and Environmental Sciences.

Safety and immunogenicity of adjuvanted inactivated split-virion and whole-virion influenza A (H5N1) vaccines in children: a phase I-II randomized trial.

Zijian Feng, Changgui Li, Jiang Wu, 2010, Vaccine.

Preparation of PrP-specific Polyclonal Antibody via Immunization of PRNP-knockout Mice with Recombinant Human PrP Protein.

X. Yang, Qiang Shi, Xiao-Ping Dong, 2020, Biomedical and environmental sciences : BES.

Remarkable reductions of PAKs in the brain tissues of scrapie-infected rodent possibly linked closely with neuron loss

Jing Wang, Qiang Shi, Cao Chen, 2014, Medical Microbiology and Immunology.

Changes of tau profiles in brains of the hamsters infected with scrapie strains 263 K or 139 A possibly associated with the alteration of phosphate kinases

Cao Chen, Chen Gao, C. Tian, 2010, BMC infectious diseases.

Detection and Analysis of Ebola Virus in Sierra Leone-China Friendship Biosafety Laboratory from March 11 to April 20, 2015.

Xiao-Ping Dong, Kun Cai, Qin Wang, 2016, Biomedical and environmental sciences : BES.