Ryan P. Bingham

发表

The Major Head Protein of Bacteriophage T4 Binds Specifically to Elongation Factor Tu*

C. Kleanthous, L. Snyder, Ryan P. Bingham, 2000, The Journal of Biological Chemistry.

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Juan A. Bueren-Calabuig, David W. Gray, Frederick R. C. Simeons, 2019, Proceedings of the National Academy of Sciences.

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

David M. Wilson, G. Drewes, D. Eberhard, 2015, Nature chemical biology.

Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140

D. Zwijnenburg, W. D. de Jonge, R. Prinjha, 2020, bioRxiv.

Reducing False Positives through the Application of Fluorescence Lifetime Technology: A Comparative Study Using TYK2 Kinase as a Model System

P. Rowland, P. Craggs, Bhumika Karamshi, 2021, SLAS discovery : advancing life sciences R & D.

Novel Selection Approaches to Identify Antibodies Targeting Neoepitopes on the C5b6 Intermediate Complex to Inhibit Membrane Attack Complex Formation

Darren A. Gormley, C. Harris, J. E. Clarkson, 2021, Antibodies.

Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors.

A. Hovnanian, J. Liddle, P. Thomas, 2019, Bioorganic & medicinal chemistry letters.

Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140

D. Zwijnenburg, W. D. de Jonge, R. Prinjha, 2022, BMC Biology.

The Aspartyl Protease Ddi1 Is Essential for Erythrocyte Invasion by the Malaria Parasite

L. Collinson, D. Powell, S. Howell, 2021, bioRxiv.

Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening.

S. Pickett, C. Chung, C. Jamieson, 2016, Journal of medicinal chemistry.

Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors.

C. Chung, E. Nicodème, C. Arico-Muendel, 2016, ACS medicinal chemistry letters.

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.

S. Pickett, C. Chung, E. Nicodème, 2015, Journal of medicinal chemistry.

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library.

C. Chung, A. Satz, M. Clark, 2015, ACS medicinal chemistry letters.

A potent and selective Kallikrein-5 inhibitor delivers high pharmacological activity in Netherton Syndrome patient skin.

M. Lennon, A. Hovnanian, D. Grillot, 2021, The Journal of investigative dermatology.