Attila Gursoy

发表

Fast and accurate modeling of protein–protein interactions by combining template‐interface‐based docking with flexible refinement

Ozlem Keskin, Ruth Nussinov, Nurcan Tuncbag, 2012, Proteins.

Prediction of Protein Interactions by Structural Matching: Prediction of PPI Networks and the Effects of Mutations on PPIs that Combines Sequence and Structural Information.

Ozlem Keskin, Ruth Nussinov, Nurcan Tuncbag, 2017, Methods in molecular biology.

Towards inferring time dimensionality in protein–protein interaction networks by integrating structures: the p53 example† †This article is part of a Molecular BioSystems themed issue on Computational and Systems Biology.

Ozlem Keskin, Ruth Nussinov, Nurcan Tuncbag, 2009, Molecular bioSystems.

PRISM-EM: template interface-based modelling of multi-protein complexes guided by cryo-electron microscopy density maps. Corrigendum.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2016, Acta crystallographica. Section D, Structural biology.

PRISM: protein-protein interaction prediction by structural matching.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2008, Methods in molecular biology.

Developments in integrative modeling with dynamical interfaces.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2019, Current opinion in structural biology.

3D spatial organization and network-guided comparison of mutation profiles in Glioblastoma reveals similarities across patients

Ozlem Keskin, Attila Gursoy, Cansu Dincer, 2019, bioRxiv.

Analysis and network representation of hotspots in protein interfaces using minimum cut trees

Ozlem Keskin, Nurcan Tuncbag, Attila Gursoy, 2010, Proteins.

Topological properties of protein interaction networks from a structural perspective.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2008, Biochemical Society transactions.

Advances in template-based protein docking by utilizing interfaces towards completing structural interactome.

Attila Gursoy, Emine Guven-Maiorov, Serena Muratcioglu, 2015, Current opinion in structural biology.

Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing.

Ozlem Keskin, Ruth Nussinov, Farideh Halakou, 2018, Methods in molecular biology.

Architectures and functional coverage of protein-protein interfaces.

Ozlem Keskin, Ruth Nussinov, Nurcan Tuncbag, 2008, Journal of molecular biology.

GTP-dependent K-Ras dimerization

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2015 .

K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target?

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2016, Expert opinion on therapeutic targets.

GTP-Dependent K-Ras Dimerization.

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2015, Structure.

Enriching the human apoptosis pathway by predicting the structures of protein-protein complexes.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2012, Journal of structural biology.

Hot spots in protein-protein interfaces: towards drug discovery.

Ozlem Keskin, Attila Gursoy, Engin Cukuroglu, 2014, Progress in biophysics and molecular biology.

Protein-protein interfaces integrated into interaction networks: implications on drug design.

Ozlem Keskin, Gozde Kar, Attila Gursoy, 2012, Current pharmaceutical design.

Relationships between unfolded configurations of proteins and dynamics of folding to the native state

Ozlem Keskin, Burak Erman, Metin Turkay, 2006 .

Constructing structural networks of signaling pathways on the proteome scale.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2012, Current opinion in structural biology.

Plasma membrane regulates Ras signaling networks

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2015, Cellular logistics.

Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2015, Biophysical journal.

PRISM-EM: template interface-based modelling of multi-protein complexes guided by cryo-electron microscopy density maps.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2016, Acta crystallographica. Section D, Structural biology.

The structural network of inflammation and cancer: merits and challenges.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2013, Seminars in cancer biology.

Ras Conformational Ensembles, Allostery, and Signaling.

Ozlem Keskin, Ruth Nussinov, Shaoyong Lu, 2016, Chemical reviews.

Structural and functional analysis of perforin mutations in association with clinical data of familial hemophagocytic lymphohistiocytosis type 2 (FHL2) patients

Ozlem Keskin, Attila Gursoy, Omer An, 2013, Protein science : a publication of the Protein Society.

Integrating Structure to Protein-Protein Interaction Networks That Drive Metastasis to Brain and Lung in Breast Cancer

Ozlem Keskin, Emre Guney, Attila Gursoy, 2013, PloS one.

Analysis of Hot Region Organization in Hub Proteins

Ozlem Keskin, Attila Gursoy, Engin Cukuroglu, 2010, Annals of Biomedical Engineering.

Molecular Recognition of H3/H4 Histone Tails by the Tudor Domains of JMJD2A: A Comparative Molecular Dynamics Simulations Study

Ozlem Keskin, Burak Erman, Attila Gursoy, 2011, PloS one.

Principles of Protein—Protein Interactions: What Are the Preferred Ways for Proteins to Interact?

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2008 .

VitAL: Viterbi Algorithm for de novo Peptide Design

Burak Erman, Attila Gursoy, B. Erman, 2010, PloS one.

Conformational energies and entropies of peptides, and the peptide–protein binding problem

Burak Erman, Attila Gursoy, B. Erman, 2009, Physical biology.

Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2018, The Journal of Biological Chemistry.

Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2015, Expert review of proteomics.

Prediction of protein–protein interactions: unifying evolution and structure at protein interfaces

Ozlem Keskin, Nurcan Tuncbag, Attila Gursoy, 2011, Physical biology.

The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2015, Molecular Cancer Research.

Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers.

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2016, The Biochemical journal.

3D spatial organization and network-guided comparison of mutation profiles in Glioblastoma reveals similarities across patients

Ozlem Keskin, Nurcan Tuncbag, Attila Gursoy, 2019, PLoS computational biology.

The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway

Ozlem Keskin, Ruth Nussinov, Chung-Jung Tsai, 2015, Scientific Reports.

Co-Occurring Atomic Contacts for the Characterization of Protein Binding Hot Spots

Jiangning Song, Qian Liu, Jinyan Li, 2015, PloS one.

Characterization and prediction of protein interfaces to infer protein-protein interaction networks.

Ozlem Keskin, Nurcan Tuncbag, Attila Gursoy, 2008, Current pharmaceutical biotechnology.

A Structural View of Negative Regulation of the Toll-like Receptor-Mediated Inflammatory Pathway.

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2015, Biophysical journal.

The structural network of Interleukin-10 and its implications in inflammation and cancer

Ozlem Keskin, Ruth Nussinov, Attila Gursoy, 2014, BMC Genomics.

Identification of Interconnected Markers for T-Cell Acute Lymphoblastic Leukemia

Ozlem Keskin, Attila Gursoy, O. Keskin, 2013, BioMed research international.