Anja Hombach

CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation.

A. Schmidt, D. Kofler, C. Wendtner, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Effective Proliferation of Human Regulatory T Cells Requires a Strong Costimulatory CD28 Signal That Cannot Be Substituted by IL-21

D. Kofler, H. Abken, A. Hombach, 2007, The Journal of Immunology.